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Found 41 Enz. Inhib. hit(s) with all data for entry = 50018040
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  4nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  5nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  36nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  330nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  340nMAssay Description:Inhibition of ovine COX2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)
Affinity DataIC50:  380nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  440nMAssay Description:Inhibition of ovine COX2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50140278(4-((E)-4-Amino-2-methylsulfanyl-phenylazo)-benzene...)
Affinity DataIC50:  2.04E+3nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)
Affinity DataIC50:  2.84E+3nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)
Affinity DataIC50:  3.49E+3nMAssay Description:Inhibition of ovine COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190336(4-((3,4-dimethoxyphenyl)diazenyl)benzenesulfonamid...)
Affinity DataIC50:  4.28E+3nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190337(5-{[4-(aminosulfonyl)phenyl]diazenyl}-2-hydroxyben...)
Affinity DataIC50:  8.89E+3nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190333(2-[(phenylcarbamoyl)oxy]-4-[(E)-2-(4-sulfamoylphen...)
Affinity DataIC50:  1.11E+4nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190335(4-((3-chloro-4-hydroxyphenyl)diazenyl)benzenesulfo...)
Affinity DataIC50:  1.13E+4nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190338(2-({[4-(propan-2-yl)phenyl]carbamoyl}oxy)-4-[(E)-2...)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190334(4-((3,4-dihydroxyphenyl)diazenyl)benzenesulfonamid...)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190339(4-((4-methoxyphenyl)diazenyl)benzenesulfonamide | ...)
Affinity DataIC50:  1.46E+4nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190332(4-((4-hydroxy-3-methoxyphenyl)diazenyl)benzenesulf...)
Affinity DataIC50:  1.69E+4nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50140278(4-((E)-4-Amino-2-methylsulfanyl-phenylazo)-benzene...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of ovine COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50140278(4-((E)-4-Amino-2-methylsulfanyl-phenylazo)-benzene...)
Affinity DataIC50:  2.33E+4nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190337(5-{[4-(aminosulfonyl)phenyl]diazenyl}-2-hydroxyben...)
Affinity DataIC50:  2.36E+4nMAssay Description:Inhibition of ovine COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190338(2-({[4-(propan-2-yl)phenyl]carbamoyl}oxy)-4-[(E)-2...)
Affinity DataIC50:  2.63E+4nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  2.66E+4nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190337(5-{[4-(aminosulfonyl)phenyl]diazenyl}-2-hydroxyben...)
Affinity DataIC50:  2.93E+4nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190337(5-{[4-(aminosulfonyl)phenyl]diazenyl}-2-hydroxyben...)
Affinity DataIC50:  3.16E+4nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)
Affinity DataIC50:  3.32E+4nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190335(4-((3-chloro-4-hydroxyphenyl)diazenyl)benzenesulfo...)
Affinity DataIC50:  3.33E+4nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50140278(4-((E)-4-Amino-2-methylsulfanyl-phenylazo)-benzene...)
Affinity DataIC50:  3.41E+4nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190333(2-[(phenylcarbamoyl)oxy]-4-[(E)-2-(4-sulfamoylphen...)
Affinity DataIC50:  3.51E+4nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190335(4-((3-chloro-4-hydroxyphenyl)diazenyl)benzenesulfo...)
Affinity DataIC50:  3.97E+4nMAssay Description:Inhibition of ovine COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190335(4-((3-chloro-4-hydroxyphenyl)diazenyl)benzenesulfo...)
Affinity DataIC50:  4.05E+4nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190334(4-((3,4-dihydroxyphenyl)diazenyl)benzenesulfonamid...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190336(4-((3,4-dimethoxyphenyl)diazenyl)benzenesulfonamid...)
Affinity DataIC50:  6.17E+4nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190340(4-((3-hydroxy-4-methoxyphenyl)diazenyl)benzenesulf...)
Affinity DataIC50:  6.64E+4nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190336(4-((3,4-dimethoxyphenyl)diazenyl)benzenesulfonamid...)
Affinity DataIC50:  8.45E+4nMAssay Description:Inhibition of ovine COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190336(4-((3,4-dimethoxyphenyl)diazenyl)benzenesulfonamid...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190332(4-((4-hydroxy-3-methoxyphenyl)diazenyl)benzenesulf...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190339(4-((4-methoxyphenyl)diazenyl)benzenesulfonamide | ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM33266(CHEMBL379206 | azo-sulfonamide, 1a | p-Phenyldiaze...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM33269(CHEMBL277836 | azo-sulfonamide, 1d | cid_75522 | p...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed