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Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 2088
TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16735(N-(2-{4-[(3R)-3-hydroxy-3-phenylpropyl]piperazin-1...)
Affinity DataIC50:  46nMpH: 7.5 T: 25°CAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16733(4-[1-(5-Amino)-pentyl]-1-{4-(phenyl)-2-[(naphthale...)
Affinity DataIC50:  68nMpH: 7.5 T: 25°CAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16734(N-(2-{4-[(3S)-3-hydroxy-3-phenylpropyl]piperazin-1...)
Affinity DataIC50:  69nMpH: 7.5 T: 25°CAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16736(N-[2-(4-benzoylpiperazin-1-yl)-5-phenylphenyl]naph...)
Affinity DataIC50:  79nMpH: 7.5 T: 25°CAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16727(N-{5-bromo-2-[4-(2-hydroxyethyl)piperazin-1-yl]phe...)
Affinity DataIC50:  79nMpH: 7.5 T: 25°CAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16731(Naphthyl Compound, 5b | ethyl 2-{4-[2-(naphthalene...)
Affinity DataIC50:  90nMpH: 7.5 T: 25°CAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16732(1-{4-(Phenyl)-2-[(naphthalene-1-carbonyl)-amino]-p...)
Affinity DataIC50:  100nMpH: 7.5 T: 25°CAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16730(N-{2-[4-(2-hydroxyethyl)piperazin-1-yl]-5-phenylph...)
Affinity DataIC50:  110nMpH: 7.5 T: 25°CAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16749(Coumarin Compound, 11c | N-[2-(4-benzylpiperazin-1...)
Affinity DataIC50:  151nMAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16729(N-[5-phenyl-2-(piperazin-1-yl)phenyl]naphthalene-1...)
Affinity DataIC50:  300nMpH: 7.5 T: 25°CAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16750(2,2,2-trifluoroacetic acid; 2-oxo-N-[5-phenyl-2-(p...)
Affinity DataIC50:  580nMAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16742(Coumarin Compound, 9e | N-{5-bromo-2-[4-(2-hydroxy...)
Affinity DataIC50:  630nMAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16741(2,2,2-trifluoroacetic acid; N-[5-bromo-2-(piperazi...)
Affinity DataIC50:  670nMAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16740(CHEMBL206442 | Coumarin Compound, 9c | N-[2-(4-ben...)
Affinity DataIC50:  760nMAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16724(CHEMBL381618 | Naphthyl Compound, 3b | tert-butyl ...)
Affinity DataIC50: >1.00E+3nMpH: 7.5 T: 25°CAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16747(Coumarin Compound, 10e | N-{5-bromo-2-[4-(2-hydrox...)
Affinity DataIC50:  1.00E+3nMAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16739(CHEMBL207083 | Coumarin Compound, 9b | tert-butyl ...)
Affinity DataIC50:  1.00E+3nMAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16744(CHEMBL206854 | Coumarin Compound, 10b | tert-butyl...)
Affinity DataIC50: >1.00E+3nMAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16726(CHEMBL203120 | N-[5-bromo-2-(piperazin-1-yl)phenyl...)
Affinity DataIC50:  1.00E+3nMpH: 7.5 T: 25°CAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16728(N-[2-(4-benzylpiperazin-1-yl)-5-phenylphenyl]napht...)
Affinity DataIC50:  1.25E+3nMpH: 7.5 T: 25°CAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16737(N-(2-{4-[5-(1,2-dithiolan-3-yl)pentanoyl]piperazin...)
Affinity DataIC50:  3.80E+3nMpH: 7.5 T: 25°CAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16725(CHEMBL380521 | N-[2-(4-benzylpiperazin-1-yl)-5-bro...)
Affinity DataIC50: >5.00E+3nMpH: 7.5 T: 25°CAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16745(CHEMBL381617 | Coumarin Compound, 10c | N-[2-(4-be...)
Affinity DataIC50: >5.00E+3nMAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16746(2,2,2-trifluoroacetic acid; N-[5-bromo-2-(piperazi...)
Affinity DataIC50:  5.00E+3nMAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16738(Coumarin Compound, 9a | N-[5-bromo-2-(morpholin-4-...)
Affinity DataIC50: >1.00E+4nMAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16748(Coumarin Compound, 11b | tert-butyl 4-{2-[(2-oxo-2...)
Affinity DataIC50:  1.00E+4nMAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16743(Coumarin Compound, 10a | N-[5-bromo-2-(morpholin-4...)
Affinity DataIC50: >1.00E+4nMAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16723(N-[5-bromo-2-(morpholin-4-yl)phenyl]naphthalene-1-...)
Affinity DataIC50: >2.00E+4nMpH: 7.5 T: 25°CAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed