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Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50018131
TargetMelanin-concentrating hormone receptor 1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191756(4'-fluoro-biphenyl-4-carboxylic acid methyl-(3-pip...)
Affinity DataKi:  31nMAssay Description:Binding affinity to MCHR1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191752(6-(4-chlorophenyl)-3-((3-((4-hydroxypiperidin-1-yl...)
Affinity DataKi:  51nMAssay Description:Binding affinity to MCHR1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191768(6-(4-chlorophenyl)-3-((3-(pyrrolidin-1-ylmethyl)qu...)
Affinity DataKi:  91nMAssay Description:Binding affinity to MCHR1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191765(4'-fluoro-biphenyl-4-carboxylic acid (3-diethylami...)
Affinity DataKi:  102nMAssay Description:Binding affinity to MCHR1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191753(6-(4-chlorophenyl)-3-((3-((4-methylpiperazin-1-yl)...)
Affinity DataKi:  110nMAssay Description:Binding affinity to MCHR1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191766(6-(4-chlorophenyl)-3-((3-((diethylamino)methyl)qui...)
Affinity DataKi:  126nMAssay Description:Binding affinity to MCHR1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191755(2-(((8-((6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyri...)
Affinity DataKi:  136nMAssay Description:Binding affinity to MCHR1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191764(4'-fluoro-biphenyl-4-carboxylic acid [3-((S)-3-hyd...)
Affinity DataKi:  142nMAssay Description:Binding affinity to MCHR1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191761(4'-fluoro-biphenyl-4-carboxylic acid [3-(4-hydroxy...)
Affinity DataKi:  195nMAssay Description:Binding affinity to MCHR1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191762(6-(4-chlorophenyl)-3-((3-((dimethylamino)methyl)qu...)
Affinity DataKi:  197nMAssay Description:Binding affinity to MCHR1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191754(CHEMBL213817 | N-(3-diethylaminomethyl-quinolin-8-...)
Affinity DataKi:  310nMAssay Description:Binding affinity to MCHR1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191767(4'-fluoro-biphenyl-4-carboxylic acid [3-(4-methane...)
Affinity DataKi:  310nMAssay Description:Binding affinity to MCHR1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191760(CHEMBL216038 | N-(3-dimethylaminomethyl-quinolin-8...)
Affinity DataKi:  414nMAssay Description:Binding affinity to MCHR1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191759(6-(4-chlorophenyl)-3-((3-((4-(methylsulfonyl)piper...)
Affinity DataKi:  773nMAssay Description:Binding affinity to MCHR1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191750(6-(4-fluoro-phenyl)-N-[3-(4-hydroxy-piperidin-1-yl...)
Affinity DataKi:  803nMAssay Description:Binding affinity to MCHR1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191763(6-(4-fluoro-phenyl)-N-[3-((S)-3-hydroxy-pyrrolidin...)
Affinity DataKi:  1.15E+3nMAssay Description:Binding affinity to MCHR1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191758(4'-fluoro-biphenyl-4-carboxylic acid (3-morpholin-...)
Affinity DataKi:  1.41E+3nMAssay Description:Binding affinity to MCHR1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191751(6-(4-fluoro-phenyl)-N-[3-(4-methyl-piperazin-1-ylm...)
Affinity DataKi:  3.54E+3nMAssay Description:Binding affinity to MCHR1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191757(6-(4-fluoro-phenyl)-N-(3-morpholin-4-ylmethyl-quin...)
Affinity DataKi:  2.01E+4nMAssay Description:Binding affinity to MCHR1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191762(6-(4-chlorophenyl)-3-((3-((dimethylamino)methyl)qu...)
Affinity DataIC50:  1.31E+3nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191761(4'-fluoro-biphenyl-4-carboxylic acid [3-(4-hydroxy...)
Affinity DataIC50:  2.81E+3nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191764(4'-fluoro-biphenyl-4-carboxylic acid [3-((S)-3-hyd...)
Affinity DataIC50:  3.60E+3nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191765(4'-fluoro-biphenyl-4-carboxylic acid (3-diethylami...)
Affinity DataIC50:  4.16E+3nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191756(4'-fluoro-biphenyl-4-carboxylic acid methyl-(3-pip...)
Affinity DataIC50:  4.19E+3nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191758(4'-fluoro-biphenyl-4-carboxylic acid (3-morpholin-...)
Affinity DataIC50:  7.47E+3nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191760(CHEMBL216038 | N-(3-dimethylaminomethyl-quinolin-8...)
Affinity DataIC50:  1.03E+4nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191754(CHEMBL213817 | N-(3-diethylaminomethyl-quinolin-8-...)
Affinity DataIC50:  1.41E+4nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191750(6-(4-fluoro-phenyl)-N-[3-(4-hydroxy-piperidin-1-yl...)
Affinity DataIC50:  1.46E+4nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191763(6-(4-fluoro-phenyl)-N-[3-((S)-3-hydroxy-pyrrolidin...)
Affinity DataIC50:  1.65E+4nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191751(6-(4-fluoro-phenyl)-N-[3-(4-methyl-piperazin-1-ylm...)
Affinity DataIC50:  2.02E+4nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191766(6-(4-chlorophenyl)-3-((3-((diethylamino)methyl)qui...)
Affinity DataIC50:  2.52E+4nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191753(6-(4-chlorophenyl)-3-((3-((4-methylpiperazin-1-yl)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191767(4'-fluoro-biphenyl-4-carboxylic acid [3-(4-methane...)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191755(2-(((8-((6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyri...)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191757(6-(4-fluoro-phenyl)-N-(3-morpholin-4-ylmethyl-quin...)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191759(6-(4-chlorophenyl)-3-((3-((4-(methylsulfonyl)piper...)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191752(6-(4-chlorophenyl)-3-((3-((4-hydroxypiperidin-1-yl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191768(6-(4-chlorophenyl)-3-((3-(pyrrolidin-1-ylmethyl)qu...)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed