Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 85 Enz. Inhib. hit(s) with all data for entry = 50018206
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192791(2-(5-bromo-pyridin-2-yloxy)-N-((1R,2S,5R,7S)-5-car...)
Affinity DataIC50:  4nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192792(CHEMBL219348 | N-((1R,2S,5R,7S)-5-carbamoylmethyl-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192791(2-(5-bromo-pyridin-2-yloxy)-N-((1R,2S,5R,7S)-5-car...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192797(2-(4-chloro-phenoxy)-N-[(1R,2S,5S,7S)-5-(1H-imidaz...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192792(CHEMBL219348 | N-((1R,2S,5R,7S)-5-carbamoylmethyl-...)
Affinity DataIC50:  11nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192797(2-(4-chloro-phenoxy)-N-[(1R,2S,5S,7S)-5-(1H-imidaz...)
Affinity DataIC50:  11nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192798(CHEMBL219349 | N-((1R,2S,5R,7S)-5-carbamoylmethyl-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192791(2-(5-bromo-pyridin-2-yloxy)-N-((1R,2S,5R,7S)-5-car...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192790(2-(4-chloro-phenoxy)-N-[(1R,2S,5S,7S)-5-(N-hydroxy...)
Affinity DataIC50:  26nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192785(CHEMBL385176 | N-((1R,2S,5R,7S)-5-carbamoylmethyl-...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192795(CHEMBL219081 | N-((1R,2S,5R,7S)-5-carbamoylmethyl-...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192800(2-(4-chloro-phenoxy)-N-((1R,2S,5S,7S)-5-isoxazol-5...)
Affinity DataIC50:  31nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192787(CHEMBL219136 | N-[(1R,2S,5S,7S)-5-(5-amino-4H-[1,2...)
Affinity DataIC50:  35nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192785(CHEMBL385176 | N-((1R,2S,5R,7S)-5-carbamoylmethyl-...)
Affinity DataIC50:  36nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192792(CHEMBL219348 | N-((1R,2S,5R,7S)-5-carbamoylmethyl-...)
Affinity DataIC50:  38nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192790(2-(4-chloro-phenoxy)-N-[(1R,2S,5S,7S)-5-(N-hydroxy...)
Affinity DataIC50:  39nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192789(2-(4-chloro-phenoxy)-2-methyl-N-[(1S,2S,5R,7S)-5-(...)
Affinity DataIC50:  41nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192786(CHEMBL216976 | N-((1R,2S,5R,7S)-5-carbamoylmethyl-...)
Affinity DataIC50:  44nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192801(CHEMBL220414 | {(1R,4S,5R,7S)-4-[2-(4-chloro-pheno...)
Affinity DataIC50:  45nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192799(CHEMBL375979 | N-((1R,2S,5R,7S)-5-carbamoylmethyl-...)
Affinity DataIC50:  47nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192786(CHEMBL216976 | N-((1R,2S,5R,7S)-5-carbamoylmethyl-...)
Affinity DataIC50:  51nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192787(CHEMBL219136 | N-[(1R,2S,5S,7S)-5-(5-amino-4H-[1,2...)
Affinity DataIC50:  53nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192799(CHEMBL375979 | N-((1R,2S,5R,7S)-5-carbamoylmethyl-...)
Affinity DataIC50:  59nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192798(CHEMBL219349 | N-((1R,2S,5R,7S)-5-carbamoylmethyl-...)
Affinity DataIC50:  65nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192800(2-(4-chloro-phenoxy)-N-((1R,2S,5S,7S)-5-isoxazol-5...)
Affinity DataIC50:  71nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192793(3-{(1R,4S,5R,7S)-4-[2-(4-chloro-phenoxy)-2-methyl-...)
Affinity DataIC50:  74nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192801(CHEMBL220414 | {(1R,4S,5R,7S)-4-[2-(4-chloro-pheno...)
Affinity DataIC50:  82nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192789(2-(4-chloro-phenoxy)-2-methyl-N-[(1S,2S,5R,7S)-5-(...)
Affinity DataIC50:  87nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192793(3-{(1R,4S,5R,7S)-4-[2-(4-chloro-phenoxy)-2-methyl-...)
Affinity DataIC50:  89nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192801(CHEMBL220414 | {(1R,4S,5R,7S)-4-[2-(4-chloro-pheno...)
Affinity DataIC50:  92nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192788(2-(4-chloro-phenoxy)-2-methyl-N-[(1R,2S,5S,7S)-5-(...)
Affinity DataIC50:  101nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192800(2-(4-chloro-phenoxy)-N-((1R,2S,5S,7S)-5-isoxazol-5...)
Affinity DataIC50:  105nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192797(2-(4-chloro-phenoxy)-N-[(1R,2S,5S,7S)-5-(1H-imidaz...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192789(2-(4-chloro-phenoxy)-2-methyl-N-[(1S,2S,5R,7S)-5-(...)
Affinity DataIC50:  119nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192790(2-(4-chloro-phenoxy)-N-[(1R,2S,5S,7S)-5-(N-hydroxy...)
Affinity DataIC50:  124nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192796(CHEMBL219575 | N-[(1R,2S,5S,7S)-5-(5-amino-4-cyano...)
Affinity DataIC50:  146nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192798(CHEMBL219349 | N-((1R,2S,5R,7S)-5-carbamoylmethyl-...)
Affinity DataIC50:  165nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192799(CHEMBL375979 | N-((1R,2S,5R,7S)-5-carbamoylmethyl-...)
Affinity DataIC50:  169nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192794(CHEMBL216977 | N-((1R,2S,5R,7S)-5-carbamoylmethyl-...)
Affinity DataIC50:  185nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192796(CHEMBL219575 | N-[(1R,2S,5S,7S)-5-(5-amino-4-cyano...)
Affinity DataIC50:  205nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192795(CHEMBL219081 | N-((1R,2S,5R,7S)-5-carbamoylmethyl-...)
Affinity DataIC50:  246nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192796(CHEMBL219575 | N-[(1R,2S,5S,7S)-5-(5-amino-4-cyano...)
Affinity DataIC50:  306nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192795(CHEMBL219081 | N-((1R,2S,5R,7S)-5-carbamoylmethyl-...)
Affinity DataIC50:  310nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192788(2-(4-chloro-phenoxy)-2-methyl-N-[(1R,2S,5S,7S)-5-(...)
Affinity DataIC50:  358nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192785(CHEMBL385176 | N-((1R,2S,5R,7S)-5-carbamoylmethyl-...)
Affinity DataIC50:  373nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192786(CHEMBL216976 | N-((1R,2S,5R,7S)-5-carbamoylmethyl-...)
Affinity DataIC50:  444nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192793(3-{(1R,4S,5R,7S)-4-[2-(4-chloro-phenoxy)-2-methyl-...)
Affinity DataIC50:  455nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192787(CHEMBL219136 | N-[(1R,2S,5S,7S)-5-(5-amino-4H-[1,2...)
Affinity DataIC50:  476nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192794(CHEMBL216977 | N-((1R,2S,5R,7S)-5-carbamoylmethyl-...)
Affinity DataIC50:  519nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50192788(2-(4-chloro-phenoxy)-2-methyl-N-[(1R,2S,5S,7S)-5-(...)
Affinity DataIC50:  532nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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