Compile Data Set for Download or QSAR
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Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50037757
TargetMu-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194242(CHEMBL378082 | H-Dmt-Tic-NH-CH[(CH2)4-NH-Ac]-Bid)
Affinity DataKi:  0.130nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194244(CHEMBL212172 | H-Dmt-Tic-NH-(D)-CH[(CH2)4-NH-Z]-Bi...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194237(CHEMBL377960 | H-Dmt-Tic-NH-CH[(CH2)4-NH2]-Bid)
Affinity DataKi:  0.160nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194242(CHEMBL378082 | H-Dmt-Tic-NH-CH[(CH2)4-NH-Ac]-Bid)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194238(CHEMBL386309 | H-Dmt-Tic-NH-CH[(CH2)4-NH-Z]-Bid)
Affinity DataKi:  0.370nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194244(CHEMBL212172 | H-Dmt-Tic-NH-(D)-CH[(CH2)4-NH-Z]-Bi...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194237(CHEMBL377960 | H-Dmt-Tic-NH-CH[(CH2)4-NH2]-Bid)
Affinity DataKi:  0.490nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194238(CHEMBL386309 | H-Dmt-Tic-NH-CH[(CH2)4-NH-Z]-Bid)
Affinity DataKi:  0.640nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194245(2-(2-(2-amino-3-(4-hydroxy-2,6-dimethylphenyl)prop...)
Affinity DataKi:  1.38nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194245(2-(2-(2-amino-3-(4-hydroxy-2,6-dimethylphenyl)prop...)
Affinity DataKi:  529nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Guinea pig)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50139013((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataIC50:  13.7nMAssay Description:Agonist activity at mu opioid receptor assessed as inhibition of electrically-evoked contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Guinea pig)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194237(CHEMBL377960 | H-Dmt-Tic-NH-CH[(CH2)4-NH2]-Bid)
Affinity DataIC50:  39.7nMAssay Description:Agonist activity at mu opioid receptor assessed as inhibition of electrically-evoked contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Guinea pig)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194242(CHEMBL378082 | H-Dmt-Tic-NH-CH[(CH2)4-NH-Ac]-Bid)
Affinity DataIC50:  53.9nMAssay Description:Agonist activity at mu opioid receptor assessed as inhibition of electrically-evoked contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Guinea pig)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194244(CHEMBL212172 | H-Dmt-Tic-NH-(D)-CH[(CH2)4-NH-Z]-Bi...)
Affinity DataIC50:  62.5nMAssay Description:Agonist activity at mu opioid receptor assessed as inhibition of electrically-evoked contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Guinea pig)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194238(CHEMBL386309 | H-Dmt-Tic-NH-CH[(CH2)4-NH-Z]-Bid)
Affinity DataIC50:  375nMAssay Description:Agonist activity at mu opioid receptor assessed as inhibition of electrically-evoked contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Mouse)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194238(CHEMBL386309 | H-Dmt-Tic-NH-CH[(CH2)4-NH-Z]-Bid)
Affinity DataIC50:  9.05E+3nMAssay Description:Agonist activity at delta opioid receptor assessed as inhibition of electrically-evoked contraction of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Mouse)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194244(CHEMBL212172 | H-Dmt-Tic-NH-(D)-CH[(CH2)4-NH-Z]-Bi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Agonist activity at delta opioid receptor assessed as inhibition of electrically-evoked contraction of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Mouse)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194242(CHEMBL378082 | H-Dmt-Tic-NH-CH[(CH2)4-NH-Ac]-Bid)
Affinity DataIC50: >1.00E+4nMAssay Description:Agonist activity at delta opioid receptor assessed as inhibition of electrically-evoked contraction of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Mouse)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194237(CHEMBL377960 | H-Dmt-Tic-NH-CH[(CH2)4-NH2]-Bid)
Affinity DataIC50: >1.00E+4nMAssay Description:Agonist activity at delta opioid receptor assessed as inhibition of electrically-evoked contraction of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed