Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 1623
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 12693BDBM12693(1-(3-amino-1,2-benzoxazol-5-yl)-6-[4-(2-{[(3R)-3-h...)
Affinity DataKi:  0.0300nM ΔG°:  -59.5kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 12681BDBM12681(1-(3-amino-1,2-benzoxazol-5-yl)-6-(4-{2-[(dimethyl...)
Affinity DataKi:  0.0400nM ΔG°:  -58.8kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 12748BDBM12748(2-{6-[4-(2-methanesulfonylphenyl)phenyl]-7-oxo-3-(...)
Affinity DataKi:  0.120nM ΔG°:  -56.1kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 12746BDBM12746(6-[4-(2-methanesulfonylphenyl)phenyl]-1-(4-methoxy...)
Affinity DataKi:  0.180nM ΔG°:  -55.1kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 12747BDBM12747(2-{6-[4-(2-methanesulfonylphenyl)phenyl]-7-oxo-3-(...)
Affinity DataKi:  0.180nM ΔG°:  -55.1kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 12733BDBM12733(3-[6-(4-{2-[(dimethylamino)methyl]phenyl}phenyl)-7...)
Affinity DataKi:  0.180nM ΔG°:  -55.1kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 12749BDBM12749(1-(2-amino-4-methoxyphenyl)-6-[4-(2-methanesulfony...)
Affinity DataKi:  0.200nM ΔG°:  -54.8kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 12740BDBM12740(6-(4-{2-[(dimethylamino)methyl]phenyl}phenyl)-1-(4...)
Affinity DataKi:  0.350nM ΔG°:  -53.4kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 12742BDBM12742(3-{6-[4-(2-{[(3R)-3-hydroxypyrrolidin-1-yl]methyl}...)
Affinity DataKi:  0.720nM ΔG°:  -51.7kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 12744BDBM12744(2-{6-[4-(2-methanesulfonylphenyl)phenyl]-7-oxo-3-(...)
Affinity DataKi:  0.740nM ΔG°:  -51.6kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 12743BDBM12743(6-[4-(2-{[(3R)-3-hydroxypyrrolidin-1-yl]methyl}phe...)
Affinity DataKi:  0.760nM ΔG°:  -51.5kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 12730BDBM12730(2-[6-(4-{2-[(dimethylamino)methyl]phenyl}phenyl)-7...)
Affinity DataKi:  0.820nM ΔG°:  -51.3kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 12741BDBM12741(2-{6-[4-(2-{[(3R)-3-hydroxypyrrolidin-1-yl]methyl}...)
Affinity DataKi:  1.20nM ΔG°:  -50.4kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 12745BDBM12745(2-{6-[4-(2-methanesulfonylphenyl)phenyl]-7-oxo-3-(...)
Affinity DataKi:  2nM ΔG°:  -49.2kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 12735BDBM12735(1-(3-aminophenyl)-6-(4-{2-[(dimethylamino)methyl]p...)
Affinity DataKi:  2nM ΔG°:  -49.2kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 12739BDBM12739(6-(4-{2-[(dimethylamino)methyl]phenyl}phenyl)-1-(4...)
Affinity DataKi:  2.60nM ΔG°:  -48.5kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 12731BDBM12731(2-[6-(4-{2-[(dimethylamino)methyl]phenyl}phenyl)-7...)
Affinity DataKi:  2.70nM ΔG°:  -48.4kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 12732BDBM12732(3-[6-(4-{2-[(dimethylamino)methyl]phenyl}phenyl)-7...)
Affinity DataKi:  12nM ΔG°:  -44.8kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 12734BDBM12734(6-(4-{2-[(dimethylamino)methyl]phenyl}phenyl)-1-(3...)
Affinity DataKi:  20nM ΔG°:  -43.5kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 12738BDBM12738(N-{3-[6-(4-{2-[(dimethylamino)methyl]phenyl}phenyl...)
Affinity DataKi:  47nM ΔG°:  -41.4kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 12737BDBM12737({3-[6-(4-{2-[(dimethylamino)methyl]phenyl}phenyl)-...)
Affinity DataKi:  54nM ΔG°:  -41.1kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 12736BDBM12736(N-{3-[6-(4-{2-[(dimethylamino)methyl]phenyl}phenyl...)
Affinity DataKi:  88nM ΔG°:  -39.9kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed