Compile Data Set for Download or QSAR
maximum 50k data
Found 20 Enz. Inhib. hit(s) with all data for entry = 2331
TargetCathepsin S(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19484(1, 2, 3 -Triazole Nitrile Inhibitor, 11e | N-[(1S)...)
Affinity DataKi:  15nM ΔG°:  -46.5kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19483(1, 2, 3 -Triazole Nitrile Inhibitor, 11d | N-[(1S)...)
Affinity DataKi:  18nM ΔG°:  -46.0kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19482(1, 2, 3 -Triazole Nitrile Inhibitor, 11c | N-[(1S)...)
Affinity DataKi:  200nM ΔG°:  -39.8kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19481(1, 2, 3 -Triazole Nitrile Inhibitor, 11b | N-[(2S)...)
Affinity DataKi:  420nM ΔG°:  -37.9kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19481(1, 2, 3 -Triazole Nitrile Inhibitor, 11b | N-[(2S)...)
Affinity DataKi:  430nM ΔG°:  -37.8kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19479(1, 2, 3 -Triazole Nitrile Inhibitor, 11a | N-[(2S)...)
Affinity DataKi:  880nM ΔG°:  -36.0kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19479(1, 2, 3 -Triazole Nitrile Inhibitor, 11a | N-[(2S)...)
Affinity DataKi:  1.20E+3nM ΔG°:  -35.2kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19483(1, 2, 3 -Triazole Nitrile Inhibitor, 11d | N-[(1S)...)
Affinity DataKi:  1.70E+3nM ΔG°:  -34.3kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19482(1, 2, 3 -Triazole Nitrile Inhibitor, 11c | N-[(1S)...)
Affinity DataKi: >1.00E+4nM ΔG°: >-29.7kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19483(1, 2, 3 -Triazole Nitrile Inhibitor, 11d | N-[(1S)...)
Affinity DataKi: >1.00E+4nM ΔG°: >-29.7kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19482(1, 2, 3 -Triazole Nitrile Inhibitor, 11c | N-[(1S)...)
Affinity DataKi: >1.00E+4nM ΔG°: >-29.7kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19481(1, 2, 3 -Triazole Nitrile Inhibitor, 11b | N-[(2S)...)
Affinity DataKi: >1.00E+4nM ΔG°: >-29.7kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19479(1, 2, 3 -Triazole Nitrile Inhibitor, 11a | N-[(2S)...)
Affinity DataKi: >1.00E+4nM ΔG°: >-29.7kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19483(1, 2, 3 -Triazole Nitrile Inhibitor, 11d | N-[(1S)...)
Affinity DataKi: >1.00E+4nM ΔG°: >-29.7kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19482(1, 2, 3 -Triazole Nitrile Inhibitor, 11c | N-[(1S)...)
Affinity DataKi: >1.00E+4nM ΔG°: >-29.7kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19481(1, 2, 3 -Triazole Nitrile Inhibitor, 11b | N-[(2S)...)
Affinity DataKi: >1.00E+4nM ΔG°: >-29.7kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19479(1, 2, 3 -Triazole Nitrile Inhibitor, 11a | N-[(2S)...)
Affinity DataKi: >1.00E+4nM ΔG°: >-29.7kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19484(1, 2, 3 -Triazole Nitrile Inhibitor, 11e | N-[(1S)...)
Affinity DataKi: >1.50E+4nM ΔG°: >-28.6kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19484(1, 2, 3 -Triazole Nitrile Inhibitor, 11e | N-[(1S)...)
Affinity DataKi: >1.50E+4nM ΔG°: >-28.6kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19484(1, 2, 3 -Triazole Nitrile Inhibitor, 11e | N-[(1S)...)
Affinity DataKi: >1.50E+4nM ΔG°: >-28.6kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed