Compile Data Set for Download or QSAR
Report error Found 82 Enz. Inhib. hit(s) with all data for entry = 50018527
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196740BDBM50196740(N-((S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-di...)
Affinity DataEC50:  0.200nMAssay Description:Inhibition of BACE expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196756BDBM50196756(pyridin-3-ylmethyl (S)-1-((2S,3R)-4-(3-ethylbenzyl...)
Affinity DataEC50:  0.600nMAssay Description:Inhibition of BACE expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196755BDBM50196755(N-((S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-di...)
Affinity DataEC50:  1nMAssay Description:Inhibition of BACE expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196751BDBM50196751(N-((S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-di...)
Affinity DataIC50: 1nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196751BDBM50196751(N-((S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-di...)
Affinity DataEC50:  1nMAssay Description:Inhibition of BACE expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196750BDBM50196750(N-((S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-di...)
Affinity DataEC50:  1nMAssay Description:Inhibition of BACE expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196746BDBM50196746(N-((S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-di...)
Affinity DataIC50: 2nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196743BDBM50196743(pyridin-4-ylmethyl (S)-1-((2S,3R)-4-(3-ethylbenzyl...)
Affinity DataEC50:  2nMAssay Description:Inhibition of BACE expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196754BDBM50196754(methyl (S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,...)
Affinity DataEC50:  2nMAssay Description:Inhibition of BACE expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196755BDBM50196755(N-((S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-di...)
Affinity DataIC50: 2nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196747BDBM50196747(N-((S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-di...)
Affinity DataIC50: 2nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196745BDBM50196745(methyl (S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,...)
Affinity DataEC50:  2nMAssay Description:Inhibition of BACE expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196736BDBM50196736(benzyl (S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,...)
Affinity DataIC50: 3nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196749BDBM50196749(pyridin-4-ylmethyl (S)-1-((2S,3R)-4-(3-ethylbenzyl...)
Affinity DataIC50: 3nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196745BDBM50196745(methyl (S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,...)
Affinity DataIC50: 3nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196734BDBM50196734(N-((S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-di...)
Affinity DataEC50:  4nMAssay Description:Inhibition of BACE expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196748BDBM50196748((S)-N-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-diflu...)
Affinity DataEC50:  4nMAssay Description:Inhibition of BACE expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196744BDBM50196744(2,2,2-trifluoroethyl (S)-1-((2S,3R)-4-(3-ethylbenz...)
Affinity DataIC50: 4nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196737BDBM50196737(S-tetrahydrofuran-3-yl (S)-1-((2S,3R)-4-(3-ethylbe...)
Affinity DataEC50:  4nMAssay Description:Inhibition of BACE expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196734BDBM50196734(N-((S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-di...)
Affinity DataIC50: 4nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196733BDBM50196733(pyridin-3-ylmethyl (S)-1-((2S,3R)-4-(3-ethylbenzyl...)
Affinity DataIC50: 4nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196757BDBM50196757(N-((S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-di...)
Affinity DataEC50:  4nMAssay Description:Inhibition of BACE expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196740BDBM50196740(N-((S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-di...)
Affinity DataIC50: 4nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196731BDBM50196731(N-{(S)-2-(butane-1-sulfonyl)-1-[(1S,2R)-1-(3,5-dif...)
Affinity DataEC50:  4nMAssay Description:Inhibition of BACE expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196752BDBM50196752(N-((S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-di...)
Affinity DataIC50: 4nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196757BDBM50196757(N-((S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-di...)
Affinity DataIC50: 4nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196754BDBM50196754(methyl (S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,...)
Affinity DataIC50: 4nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196750BDBM50196750(N-((S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-di...)
Affinity DataIC50: 5nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196733BDBM50196733(pyridin-3-ylmethyl (S)-1-((2S,3R)-4-(3-ethylbenzyl...)
Affinity DataEC50:  5nMAssay Description:Inhibition of BACE expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196749BDBM50196749(pyridin-4-ylmethyl (S)-1-((2S,3R)-4-(3-ethylbenzyl...)
Affinity DataEC50:  5nMAssay Description:Inhibition of BACE expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196758BDBM50196758(2-cyanoethyl 1-((2S,3R)-4-(3-ethylbenzylamino)-1-(...)
Affinity DataEC50:  5nMAssay Description:Inhibition of BACE expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196753BDBM50196753(N-((S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-di...)
Affinity DataIC50: 5nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196739BDBM50196739(N-((S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-di...)
Affinity DataIC50: 5nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196741BDBM50196741((S)-N-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-diflu...)
Affinity DataEC50:  6nMAssay Description:Inhibition of BACE expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196758BDBM50196758(2-cyanoethyl 1-((2S,3R)-4-(3-ethylbenzylamino)-1-(...)
Affinity DataIC50: 8nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196747BDBM50196747(N-((S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-di...)
Affinity DataEC50:  9nMAssay Description:Inhibition of BACE expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196731BDBM50196731(N-{(S)-2-(butane-1-sulfonyl)-1-[(1S,2R)-1-(3,5-dif...)
Affinity DataIC50: 10nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196756BDBM50196756(pyridin-3-ylmethyl (S)-1-((2S,3R)-4-(3-ethylbenzyl...)
Affinity DataIC50: 10nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196746BDBM50196746(N-((S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-di...)
Affinity DataEC50:  11nMAssay Description:Inhibition of BACE expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196743BDBM50196743(pyridin-4-ylmethyl (S)-1-((2S,3R)-4-(3-ethylbenzyl...)
Affinity DataIC50: 11nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196738BDBM50196738(2-acetamidoethyl (S)-1-((2S,3R)-4-(3-ethylbenzylam...)
Affinity DataEC50:  12nMAssay Description:Inhibition of BACE expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196741BDBM50196741((S)-N-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-diflu...)
Affinity DataIC50: 13nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196732BDBM50196732(N-((S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-di...)
Affinity DataEC50:  14nMAssay Description:Inhibition of BACE expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196742BDBM50196742(N-((S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-di...)
Affinity DataIC50: 15nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196737BDBM50196737(S-tetrahydrofuran-3-yl (S)-1-((2S,3R)-4-(3-ethylbe...)
Affinity DataIC50: 15nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196752BDBM50196752(N-((S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-di...)
Affinity DataEC50:  19nMAssay Description:Inhibition of BACE expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196744BDBM50196744(2,2,2-trifluoroethyl (S)-1-((2S,3R)-4-(3-ethylbenz...)
Affinity DataIC50: 19nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196736BDBM50196736(benzyl (S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,...)
Affinity DataIC50: 20nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196748BDBM50196748((S)-N-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-diflu...)
Affinity DataIC50: 22nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196739BDBM50196739(N-((S)-1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-di...)
Affinity DataEC50:  24nMAssay Description:Inhibition of BACE expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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