Compile Data Set for Download or QSAR
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Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50018540
TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human LBD of ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of human LBD of of ERalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM19459(5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50:  9.70nMAssay Description:Inhibition of human LBD of of ERalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196861(5-hydroxy-2-(4-hydroxy-2-nitrophenyl)isoindoline-1...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human LBD of of ERalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196859(4-bromo-6-hydroxy-2-(4-hydroxyphenyl)isoindoline-1...)
Affinity DataIC50:  36nMAssay Description:Inhibition of human LBD of of ERalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196858(2-(2-fluoro-4-hydroxyphenyl)-5-hydroxyisoindoline-...)
Affinity DataIC50:  53nMAssay Description:Inhibition of human LBD of of ERalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196866(5-hydroxy-2-(4-hydroxyphenyl)isoindoline-1,3-dione...)
Affinity DataIC50:  84nMAssay Description:Inhibition of human LBD of of ERalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196861(5-hydroxy-2-(4-hydroxy-2-nitrophenyl)isoindoline-1...)
Affinity DataIC50:  92nMAssay Description:Inhibition of human LBD of ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196858(2-(2-fluoro-4-hydroxyphenyl)-5-hydroxyisoindoline-...)
Affinity DataIC50:  339nMAssay Description:Inhibition of human LBD of ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM19459(5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50:  395nMAssay Description:Inhibition of human LBD of ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196860(5-hydroxy-2-(4-hydroxynaphthalen-1-yl)isoindoline-...)
Affinity DataIC50:  560nMAssay Description:Inhibition of human LBD of ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196862(5-hydroxy-2-(4-hydroxy-2-methylphenyl)isoindoline-...)
Affinity DataIC50:  802nMAssay Description:Inhibition of human LBD of of ERalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196855(5-hydroxy-2-(5-hydroxynaphthalen-1-yl)isoindoline-...)
Affinity DataIC50:  802nMAssay Description:Inhibition of human LBD of of ERalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196859(4-bromo-6-hydroxy-2-(4-hydroxyphenyl)isoindoline-1...)
Affinity DataIC50:  1.63E+3nMAssay Description:Inhibition of human LBD of ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196866(5-hydroxy-2-(4-hydroxyphenyl)isoindoline-1,3-dione...)
Affinity DataIC50:  1.98E+3nMAssay Description:Inhibition of human LBD of ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196856(2-(2,4-dimethoxyphenyl)-5-hydroxyisoindoline-1,3-d...)
Affinity DataIC50:  2.47E+3nMAssay Description:Inhibition of human LBD of of ERalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196860(5-hydroxy-2-(4-hydroxynaphthalen-1-yl)isoindoline-...)
Affinity DataIC50:  2.64E+3nMAssay Description:Inhibition of human LBD of of ERalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50088673(5-Hydroxy-2-phenyl-isoindole-1,3-dione | 5-hydroxy...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human LBD of of ERalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196862(5-hydroxy-2-(4-hydroxy-2-methylphenyl)isoindoline-...)
Affinity DataIC50:  2.81E+3nMAssay Description:Inhibition of human LBD of ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196855(5-hydroxy-2-(5-hydroxynaphthalen-1-yl)isoindoline-...)
Affinity DataIC50:  2.81E+3nMAssay Description:Inhibition of human LBD of ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196857(5-hydroxy-2-(3-hydroxyphenyl)isoindoline-1,3-dione...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of human LBD of of ERalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196864(5-hydroxy-2-(4-methoxyphenyl)isoindoline-1,3-dione...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of human LBD of of ERalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196868(2-(3,5-dimethoxyphenyl)-5-hydroxyisoindoline-1,3-d...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human LBD of ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196863(4-bromo-2-(4-hydroxyphenyl)-6-methoxyisoindoline-1...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human LBD of of ERalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196867(5-hydroxy-2-(4-methoxy-2-nitrophenyl)isoindoline-1...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human LBD of ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196867(5-hydroxy-2-(4-methoxy-2-nitrophenyl)isoindoline-1...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human LBD of of ERalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196865(5-hydroxy-2-((trans)-4-hydroxycyclohexyl)isoindoli...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human LBD of of ERalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196863(4-bromo-2-(4-hydroxyphenyl)-6-methoxyisoindoline-1...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human LBD of ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196856(2-(2,4-dimethoxyphenyl)-5-hydroxyisoindoline-1,3-d...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human LBD of ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196864(5-hydroxy-2-(4-methoxyphenyl)isoindoline-1,3-dione...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human LBD of ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196868(2-(3,5-dimethoxyphenyl)-5-hydroxyisoindoline-1,3-d...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human LBD of of ERalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196865(5-hydroxy-2-((trans)-4-hydroxycyclohexyl)isoindoli...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human LBD of ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196857(5-hydroxy-2-(3-hydroxyphenyl)isoindoline-1,3-dione...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human LBD of ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50088673(5-Hydroxy-2-phenyl-isoindole-1,3-dione | 5-hydroxy...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human LBD of ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196869(2-(4-hydroxyphenyl)isoindoline-1,3-dione | CHEMBL3...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human LBD of of ERalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50196869(2-(4-hydroxyphenyl)isoindoline-1,3-dione | CHEMBL3...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human LBD of ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed