Compile Data Set for Download or QSAR
maximum 50k data
Found 14 Enz. Inhib. hit(s) with all data for entry = 50018554
TargetEndothelin-1 receptor(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197001(CHEMBL238539 | N-[2'-(isoxazol-5-ylsulfamoyl)-4-ox...)
Affinity DataIC50:  1nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197003(CHEMBL241460 | N-[4-(3,5-dioxo-hexyl)-phenyl]-3-(2...)
Affinity DataIC50:  1.60nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197002(CHEMBL268201 | N-[4-(3,5-dioxo-hexyl)-phenyl]-3-{2...)
Affinity DataIC50:  4.60nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197000(CHEMBL429019 | N-(35-{[4-(3,5-dioxohexyl)phenyl]ca...)
Affinity DataIC50:  7.70nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197004(3-{2-[2-(2-{2-[2-(2-{2-[4-(3,5-dioxo-hexyl)-phenyl...)
Affinity DataIC50:  8nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50196999(CHEMBL413001 | N-[4-(3,5-dioxo-hexyl)-phenyl]-3-{2...)
Affinity DataIC50:  21.6nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197005(CHEMBL436821 | N-[4-{2-[2-(2-{2-[4-(3,5-dioxo-hexy...)
Affinity DataIC50:  44.9nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197003(CHEMBL241460 | N-[4-(3,5-dioxo-hexyl)-phenyl]-3-(2...)
Affinity DataIC50:  1.11E+3nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197002(CHEMBL268201 | N-[4-(3,5-dioxo-hexyl)-phenyl]-3-{2...)
Affinity DataIC50:  1.91E+3nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197000(CHEMBL429019 | N-(35-{[4-(3,5-dioxohexyl)phenyl]ca...)
Affinity DataIC50:  4.51E+3nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197004(3-{2-[2-(2-{2-[2-(2-{2-[4-(3,5-dioxo-hexyl)-phenyl...)
Affinity DataIC50:  4.69E+3nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50196999(CHEMBL413001 | N-[4-(3,5-dioxo-hexyl)-phenyl]-3-{2...)
Affinity DataIC50:  4.92E+3nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197001(CHEMBL238539 | N-[2'-(isoxazol-5-ylsulfamoyl)-4-ox...)
Affinity DataIC50:  6.00E+3nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197005(CHEMBL436821 | N-[4-{2-[2-(2-{2-[4-(3,5-dioxo-hexy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]ET1 from human ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed