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Found 40 Enz. Inhib. hit(s) with all data for entry = 50018673
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197982(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50:  6nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197996(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50:  9nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197988(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50:  30nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197982(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50:  32nMAssay Description:Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197984((S)-2-{3-[5-(3,5-dichloro-phenyl)-2-naphthalen-2-y...)
Affinity DataIC50:  43nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197978(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50:  44nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197988(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50:  54nMAssay Description:Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197993((S)-2-{3-[5-(3,5-dichloro-phenyl)-2-naphthalen-2-y...)
Affinity DataIC50:  62nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197995((S)-2-{4-[5-(3,5-dichloro-phenyl)-2-naphthalen-2-y...)
Affinity DataIC50:  63nMAssay Description:Inhibition of CCR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197981(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50:  66nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197984((S)-2-{3-[5-(3,5-dichloro-phenyl)-2-naphthalen-2-y...)
Affinity DataIC50:  68nMAssay Description:Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197999(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50:  74nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197996(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50:  83nMAssay Description:Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197991(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50:  107nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197980(4-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50:  108nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197993((S)-2-{3-[5-(3,5-dichloro-phenyl)-2-naphthalen-2-y...)
Affinity DataIC50:  118nMAssay Description:Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197978(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50:  154nMAssay Description:Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197989(4-(3-(3-chlorophenyl)-1-(naphthalen-2-yl)-1H-pyraz...)
Affinity DataIC50:  168nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197999(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50:  178nMAssay Description:Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197995((S)-2-{4-[5-(3,5-dichloro-phenyl)-2-naphthalen-2-y...)
Affinity DataIC50:  185nMAssay Description:Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198000(CHEMBL391668 | N-(5-(diethylamino)pentan-2-yl)-4-(...)
Affinity DataIC50:  207nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197980(4-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50:  209nMAssay Description:Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197980(4-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50:  220nMAssay Description:Inhibition of CCR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197995((S)-2-{4-[5-(3,5-dichloro-phenyl)-2-naphthalen-2-y...)
Affinity DataIC50:  221nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197991(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50:  225nMAssay Description:Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197981(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50:  280nMAssay Description:Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197983(4-(3-(4-chlorophenyl)-1-(naphthalen-2-yl)-1H-pyraz...)
Affinity DataIC50:  442nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197985(CHEMBL239569 | N-(5-(diethylamino)pentan-2-yl)-4-(...)
Affinity DataIC50:  522nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197992(4-(3-(3,5-bis(trifluoromethyl)phenyl)-1-(naphthale...)
Affinity DataIC50:  634nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197977(4-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50:  1.12E+3nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197979(4-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50:  1.23E+3nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197977(4-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50:  1.40E+3nMAssay Description:Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197982(3-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50:  1.61E+3nMAssay Description:Inhibition of CCR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198001(4-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50:  1.80E+3nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197998(CHEMBL239359 | N-(5-(diethylamino)pentan-2-yl)-4-(...)
Affinity DataIC50:  2.39E+3nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197994((2S)-methyl 2-(4-(3-(3,5-dichlorophenyl)-1-(naphth...)
Affinity DataIC50:  2.84E+3nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197986((S)-2-{3-[5-(3,5-dichloro-phenyl)-2-naphthalen-2-y...)
Affinity DataIC50:  4.74E+3nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197997(4-(1-(3,5-bis(trifluoromethyl)phenyl)-3-(3,5-dichl...)
Affinity DataIC50:  6.48E+3nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197987((S)-2-{4-[5-(3,5-dichloro-phenyl)-2-naphthalen-2-y...)
Affinity DataIC50:  7.60E+3nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50197990(4-(3-(3,5-dichlorophenyl)-1-(naphthalen-2-yl)-1H-p...)
Affinity DataIC50:  9.33E+3nMAssay Description:Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed