Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with all data for entry = 2085
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM16702((2R)-2-[5-(3-{[(1R)-1-(4-fluorophenyl)ethyl]carbam...)
Affinity DataKi:  42.4nM ΔG°:  -41.7kJ/molepH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM16704((2R)-2-(5-{3-[(Z)-2-(2-methylcyclopropyl)ethenyl]-...)
Affinity DataKi:  51.9nM ΔG°:  -41.2kJ/molepH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM16703((2R)-2-(5-{3-[methyl(methylsulfonyl)amino]-5-(2-me...)
Affinity DataKi:  1.65E+4nM ΔG°:  -27.0kJ/molepH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed