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Found 15 Enz. Inhib. hit(s) with all data for entry = 50018798
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198924((2S,3S)-3-((S)-1-(3,5-dichlorophenylsulfonyl)pyrro...)
Affinity DataIC50:  54nMAssay Description:Binding affinity to human VLA4 alpha4beta1 in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198928((3S)-3-((S)-1-(3,5-dichlorophenylsulfonyl)pyrrolid...)
Affinity DataIC50:  95nMAssay Description:Binding affinity to human VLA4 alpha4beta1 in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198930((3R)-3-((S)-1-(3,5-dichlorophenylsulfonyl)pyrrolid...)
Affinity DataIC50:  299nMAssay Description:Binding affinity to human VLA4 alpha4beta1 in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198933((3S)-3-((S)-1-(3,5-dichlorophenylsulfonyl)pyrrolid...)
Affinity DataIC50:  322nMAssay Description:Binding affinity to human VLA4 alpha4beta1 in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198922(2-((S)-2-(3,5-dichloro-N-methylphenylsulfonamido)-...)
Affinity DataIC50:  462nMAssay Description:Binding affinity to human VLA4 alpha4beta1 in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198934((cis)-2-((S)-1-(3,5-dichlorophenylsulfonyl)pyrroli...)
Affinity DataIC50:  525nMAssay Description:Binding affinity to human VLA4 alpha4beta1 in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198929((3S)-3-((S)-1-(3,5-dichlorophenylsulfonyl)pyrrolid...)
Affinity DataIC50:  657nMAssay Description:Binding affinity to human VLA4 alpha4beta1 in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198931((3R)-3-((S)-1-(3,5-dichlorophenylsulfonyl)pyrrolid...)
Affinity DataIC50:  1.49E+3nMAssay Description:Binding affinity to human VLA4 alpha4beta1 in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109914((S)-3-(1-(3,5-dichlorophenylsulfonyl)pyrrolidine-2...)
Affinity DataIC50:  1.50E+3nMAssay Description:Binding affinity to human VLA4 alpha4beta1 in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198927((2R,3S)-3-((S)-1-(3,5-dichlorophenylsulfonyl)pyrro...)
Affinity DataIC50:  1.60E+3nMAssay Description:Binding affinity to human VLA4 alpha4beta1 in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198923((3S)-3-((S)-1-(3,5-dichlorophenylsulfonyl)pyrrolid...)
Affinity DataIC50:  2.16E+3nMAssay Description:Binding affinity to human VLA4 alpha4beta1 in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198925((2S,3S)-3-((S)-1-(3,5-dichlorophenylsulfonyl)pyrro...)
Affinity DataIC50:  2.74E+3nMAssay Description:Binding affinity to human VLA4 alpha4beta1 in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198932((trans)-2-((S)-1-(3,5-dichlorophenylsulfonyl)pyrro...)
Affinity DataIC50:  9.46E+3nMAssay Description:Binding affinity to human VLA4 alpha4beta1 in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198924((2S,3S)-3-((S)-1-(3,5-dichlorophenylsulfonyl)pyrro...)
Affinity DataIC50:  1.30E+4nMAssay Description:Binding affinity to human integrin alpha-4-beta-7 in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198926((2R,3R)-3-((S)-1-(3,5-dichlorophenylsulfonyl)pyrro...)
Affinity DataIC50:  2.56E+4nMAssay Description:Binding affinity to human VLA4 alpha4beta1 in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed