Compile Data Set for Download or QSAR
maximum 50k data
Found 29 Enz. Inhib. hit(s) with all data for entry = 50018915
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200240(4-(4-(4-chlorobenzyl)piperazin-1-yl)-N-(2,4-dichlo...)
Affinity DataIC50:  280nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200236(4-(4-(4-chlorobenzyl)piperazin-1-yl)-N-(4-chloroph...)
Affinity DataIC50:  370nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200237(4-(4-(3,4-dichlorobenzyl)piperazin-1-yl)-N-(2,4-di...)
Affinity DataIC50:  750nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200220(4-(4-(3-chlorophenyl)piperazin-1-yl)-N-(2,4-dichlo...)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200239(5-(4-(3,4-dichlorobenzyl)piperazin-1-yl)-N-(2-chlo...)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50117922((1S,2S)-2-(2-((3-(1H-benzo[d]imidazol-2-yl)propyl)...)
Affinity DataIC50:  1.34E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200229(4-(4-(3-chlorobenzyl)piperazin-1-yl)-N-(2,4-dichlo...)
Affinity DataIC50:  1.48E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200227(4-(4-(benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-y...)
Affinity DataIC50:  1.67E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200241(4-(4-(3-chlorobenzyl)piperazin-1-yl)-N-(4-chloroph...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200246(5-(4-(4-chlorobenzyl)piperazin-1-yl)-1-(4-(2-fluor...)
Affinity DataIC50:  1.81E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200244(CHEMBL226085 | N-(2-chlorophenyl)-5-(4-(3-chloroph...)
Affinity DataIC50:  1.91E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200219(4-(4-(2-chloro-6-fluorobenzyl)piperazin-1-yl)-N-(2...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200225(5-(4-(3-chlorobenzyl)piperazin-1-yl)-1-(4-(2-fluor...)
Affinity DataIC50:  2.44E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200238(CHEMBL446375 | N-(4-chlorophenyl)-4-(4-(2-methoxyp...)
Affinity DataIC50:  2.61E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200223(CHEMBL390955 | N-(4-chlorophenyl)-4-(4-(4-chloroph...)
Affinity DataIC50:  2.64E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200245(4-(4-(benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-y...)
Affinity DataIC50:  2.73E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200234(CHEMBL224807 | N-(4-chlorophenyl)-4-(4-(3-methoxyp...)
Affinity DataIC50:  2.78E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200231(5-(4-(3,4-dichlorobenzyl)piperazin-1-yl)-1-(4-phen...)
Affinity DataIC50:  2.91E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200242(4-(4-benzylpiperazin-1-yl)-N-(2,4-dichlorophenyl)b...)
Affinity DataIC50:  3.14E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200230(4-(4-(2-chloro-6-fluorobenzyl)piperazin-1-yl)-N-(4...)
Affinity DataIC50:  3.27E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200226(CHEMBL226355 | N-(2,4-dichlorophenyl)-4-(4-(2-meth...)
Affinity DataIC50:  3.34E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200224(5-(4-(4-chlorobenzyl)piperazin-1-yl)-1-(4-phenylpi...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200228(CHEMBL387853 | N-(4-chlorophenyl)-4-(4-(4-fluoroph...)
Affinity DataIC50:  3.49E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200233(4-(4-benzylpiperazin-1-yl)-N-(4-chlorophenyl)butan...)
Affinity DataIC50:  3.52E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200243(CHEMBL226239 | N-(4-chlorophenyl)-4-(4-(2-fluoroph...)
Affinity DataIC50:  3.63E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200235(CHEMBL226406 | N-(2,4-dichlorophenyl)-4-(4-(3-meth...)
Affinity DataIC50:  3.81E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200221(CHEMBL389636 | N-(2,4-dichlorophenyl)-4-(4-phenylp...)
Affinity DataIC50:  4.21E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200222(CHEMBL226189 | N-(4-chlorophenyl)-4-(4-phenylpiper...)
Affinity DataIC50:  4.47E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50200232(CHEMBL225744 | N-(4-chlorophenyl)-4-(4-(2-chloroph...)
Affinity DataIC50:  6.01E+3nMAssay Description:Inhibition of T type calcium channel subunit alpha1G expressed in HEK293 cells assessed as effect on T-type calcium currents by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed