Compile Data Set for Download or QSAR
maximum 50k data
Found 27 Enz. Inhib. hit(s) with all data for entry = 50019003
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200783(ADS-103168 | CHEMBL424739 | N-(2-(pyrrolidin-1-yl)...)
Affinity DataIC50:  9nMAssay Description:Inhibition of MCH-mediated calcium influx into MCH-R1 expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200793(ADS-103214 | CHEMBL216430 | N-(1-methyl-2-(pyrroli...)
Affinity DataIC50:  9nMAssay Description:Inhibition of MCH-mediated calcium influx into MCH-R1 expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50150059(CHEMBL183215 | N-(4-Methyl-2-pyrrolidin-1-yl-quino...)
Affinity DataIC50:  10nMAssay Description:Inhibition of MCH-mediated calcium influx into MCH-R1 expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50150059(CHEMBL183215 | N-(4-Methyl-2-pyrrolidin-1-yl-quino...)
Affinity DataIC50:  15nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50241099(ADS-103274 | CHEMBL276393 | N-(2-((2-(dimethylamin...)
Affinity DataIC50:  25nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50241099(ADS-103274 | CHEMBL276393 | N-(2-((2-(dimethylamin...)
Affinity DataIC50:  28nMAssay Description:Inhibition of MCH-mediated calcium influx into MCH-R1 expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200783(ADS-103168 | CHEMBL424739 | N-(2-(pyrrolidin-1-yl)...)
Affinity DataIC50:  35nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200793(ADS-103214 | CHEMBL216430 | N-(1-methyl-2-(pyrroli...)
Affinity DataIC50:  40nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200790(2-(4-methoxyphenoxy)-N-(4-methyl-2-(pyrrolidin-1-y...)
Affinity DataIC50:  41nMAssay Description:Inhibition of MCH-mediated calcium influx into MCH-R1 expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200788(2-(4-chlorophenoxy)-N-(4-methyl-2-(pyrrolidin-1-yl...)
Affinity DataIC50:  58nMAssay Description:Inhibition of MCH-mediated calcium influx into MCH-R1 expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200791(ADS-103294 | CHEMBL214678 | N-(2-(isopropylamino)-...)
Affinity DataIC50:  70nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200792(ADS-102891 | CHEMBL424728 | N-(4-methyl-2-(pyrroli...)
Affinity DataIC50:  100nMAssay Description:Inhibition of MCH-mediated calcium influx into MCH-R1 expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200791(ADS-103294 | CHEMBL214678 | N-(2-(isopropylamino)-...)
Affinity DataIC50:  101nMAssay Description:Inhibition of MCH-mediated calcium influx into MCH-R1 expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200794(CHEMBL216407 | N-(2-(piperazin-1-ylmethyl)quinolin...)
Affinity DataIC50:  122nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200785(ADS-103254 | CHEMBL217712 | N-(2-((2-(dimethylamin...)
Affinity DataIC50:  164nMAssay Description:Inhibition of MCH-mediated calcium influx into MCH-R1 expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200792(ADS-102891 | CHEMBL424728 | N-(4-methyl-2-(pyrroli...)
Affinity DataIC50:  165nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200784(CHEMBL217459 | N-(2-morpholinoquinolin-6-yl)-2-(4-...)
Affinity DataIC50:  172nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200788(2-(4-chlorophenoxy)-N-(4-methyl-2-(pyrrolidin-1-yl...)
Affinity DataIC50:  250nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200785(ADS-103254 | CHEMBL217712 | N-(2-((2-(dimethylamin...)
Affinity DataIC50:  260nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200790(2-(4-methoxyphenoxy)-N-(4-methyl-2-(pyrrolidin-1-y...)
Affinity DataIC50:  390nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200789(2-(4-chlorophenoxy)-N-(2-morpholinoquinolin-6-yl)a...)
Affinity DataIC50:  961nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50241099(ADS-103274 | CHEMBL276393 | N-(2-((2-(dimethylamin...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of 5HT2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200788(2-(4-chlorophenoxy)-N-(4-methyl-2-(pyrrolidin-1-yl...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of 5HT2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200786(2-(2-chlorophenoxy)-N-(4-methyl-2-(pyrrolidin-1-yl...)
Affinity DataIC50:  1.93E+3nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200788(2-(4-chlorophenoxy)-N-(4-methyl-2-(pyrrolidin-1-yl...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of hERG in patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 2(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50241099(ADS-103274 | CHEMBL276393 | N-(2-((2-(dimethylamin...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MCH-R2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200788(2-(4-chlorophenoxy)-N-(4-methyl-2-(pyrrolidin-1-yl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of D2(L)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed