Compile Data Set for Download or QSAR
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Found 26 Enz. Inhib. hit(s) with all data for entry = 50037970
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201774(3-(dimethylamino)-1-(3-nitrophenyl)propan-1-one hy...)
Affinity DataIC50:  340nMAssay Description:Inhibition of TR by DTNB-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201776(3-(2,3-dimethylphenylamino)-1-(3-nitrophenyl)propa...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of TR by DTNB-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM34731(1-(3-nitrophenyl)-3-phenylazanyl-propan-1-one | 3-...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of TR by DTNB-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201777(2,6-di-tert-butyl-4-((2-hydroxyethylamino)methyl)p...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of TR by DTNB-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201781(CHEMBL233339 | butyl 4-(3-(3-nitrophenyl)-3-oxopro...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of TR by DTNB-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201778(3-(dimethylamino)-1-(4-(methylsulfonyl)phenyl)prop...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of TR by DTNB-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201782(1-(3,4-dichlorophenyl)-3-(dimethylamino)propan-1-o...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of TR by DTNB-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201775(3-(3-fluorophenylamino)-1-(3-nitrophenyl)propan-1-...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of TR by DTNB-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201784(1-(4-(methylsulfonyl)phenyl)-3-(piperidin-1-yl)pro...)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of TR by DTNB-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50064429(4-((dimethylamino)methyl)-2,6-diisopropylphenol | ...)
Affinity DataIC50:  1.18E+4nMAssay Description:Inhibition of TR by DTNB-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201774(3-(dimethylamino)-1-(3-nitrophenyl)propan-1-one hy...)
Affinity DataIC50:  2.03E+4nMAssay Description:Inhibition of human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201778(3-(dimethylamino)-1-(4-(methylsulfonyl)phenyl)prop...)
Affinity DataIC50:  2.04E+4nMAssay Description:Inhibition of human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201777(2,6-di-tert-butyl-4-((2-hydroxyethylamino)methyl)p...)
Affinity DataIC50:  2.49E+4nMAssay Description:Inhibition of human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201783(4-(azepan-1-ylmethyl)-2,6-di-tert-butylphenol | CH...)
Affinity DataIC50:  3.88E+4nMAssay Description:Inhibition of TR by DTNB-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM34731(1-(3-nitrophenyl)-3-phenylazanyl-propan-1-one | 3-...)
Affinity DataIC50:  5.80E+4nMAssay Description:Inhibition of human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201782(1-(3,4-dichlorophenyl)-3-(dimethylamino)propan-1-o...)
Affinity DataIC50:  6.48E+4nMAssay Description:Inhibition of human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50064429(4-((dimethylamino)methyl)-2,6-diisopropylphenol | ...)
Affinity DataIC50:  7.93E+4nMAssay Description:Inhibition of human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201776(3-(2,3-dimethylphenylamino)-1-(3-nitrophenyl)propa...)
Affinity DataIC50:  8.63E+4nMAssay Description:Inhibition of human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201784(1-(4-(methylsulfonyl)phenyl)-3-(piperidin-1-yl)pro...)
Affinity DataIC50:  1.05E+5nMAssay Description:Inhibition of human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201779(1-(3,4-dichlorophenyl)-3-(4-ethylphenylamino)propa...)
Affinity DataIC50:  1.07E+5nMAssay Description:Inhibition of TR by DTNB-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201781(CHEMBL233339 | butyl 4-(3-(3-nitrophenyl)-3-oxopro...)
Affinity DataIC50: >1.35E+5nMAssay Description:Inhibition of human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201780(1-(4-chlorophenyl)-3-morpholinopropan-1-one | CHEM...)
Affinity DataIC50:  1.48E+5nMAssay Description:Inhibition of TR by DTNB-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201783(4-(azepan-1-ylmethyl)-2,6-di-tert-butylphenol | CH...)
Affinity DataIC50: >1.55E+5nMAssay Description:Inhibition of human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201779(1-(3,4-dichlorophenyl)-3-(4-ethylphenylamino)propa...)
Affinity DataIC50: >1.57E+5nMAssay Description:Inhibition of human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201775(3-(3-fluorophenylamino)-1-(3-nitrophenyl)propan-1-...)
Affinity DataIC50: >1.73E+5nMAssay Description:Inhibition of human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50201780(1-(4-chlorophenyl)-3-morpholinopropan-1-one | CHEM...)
Affinity DataIC50: >2.12E+5nMAssay Description:Inhibition of human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed