Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 2529
TargetNuclear receptor subfamily 1 group I member 2(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM21670(N-[4-(1-cyclohexyl-2,2,2-trifluoro-1-hydroxyethyl)...)
Affinity DataIC50: 25nM EC50:  3nMpH: 8.0 T: 2°CAssay Description:Polylysine YiO imaging beads (Amersham, GE Healthcare) were coated with histidine-tagged WT PXR LBD. Nonspecific binding sites were blocked with BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM21673(N-[4-(1,1,1,3,3,4,4,5,5,5-decafluoro-2-hydroxypent...)
Affinity DataIC50: 20nM EC50:  10nMpH: 8.0 T: 2°CAssay Description:Polylysine YiO imaging beads (Amersham, GE Healthcare) were coated with histidine-tagged WT PXR LBD. Nonspecific binding sites were blocked with BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataIC50: 40nM EC50:  13nMpH: 8.0 T: 2°CAssay Description:Polylysine YiO imaging beads (Amersham, GE Healthcare) were coated with histidine-tagged WT PXR LBD. Nonspecific binding sites were blocked with BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNuclear receptor subfamily 1 group I member 2(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM21671(N-[4-(2,2,2-trifluoro-1-hydroxy-1-phenylethyl)phen...)
Affinity DataIC50: 63nM EC50:  16nMpH: 8.0 T: 2°CAssay Description:Polylysine YiO imaging beads (Amersham, GE Healthcare) were coated with histidine-tagged WT PXR LBD. Nonspecific binding sites were blocked with BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM21665(N-[4-(1,1,1-trifluoro-2-hydroxybutan-2-yl)phenyl]-...)
Affinity DataIC50: 251nM EC50:  126nMpH: 8.0 T: 2°CAssay Description:Polylysine YiO imaging beads (Amersham, GE Healthcare) were coated with histidine-tagged WT PXR LBD. Nonspecific binding sites were blocked with BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM21666(N-[4-(1,1,1-trifluoro-2-hydroxypentan-2-yl)phenyl]...)
Affinity DataIC50: 316nM EC50:  158nMpH: 8.0 T: 2°CAssay Description:Polylysine YiO imaging beads (Amersham, GE Healthcare) were coated with histidine-tagged WT PXR LBD. Nonspecific binding sites were blocked with BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM21664(N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]...)
Affinity DataIC50: 3.98E+3nM EC50:  501nMpH: 8.0 T: 2°CAssay Description:Polylysine YiO imaging beads (Amersham, GE Healthcare) were coated with histidine-tagged WT PXR LBD. Nonspecific binding sites were blocked with BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM21672(N-[4-(1,1,1-trifluoro-2-hydroxy-4-phenylbut-3-yn-2...)
Affinity DataIC50: 631nM EC50:  1.00E+3nMpH: 8.0 T: 2°CAssay Description:Polylysine YiO imaging beads (Amersham, GE Healthcare) were coated with histidine-tagged WT PXR LBD. Nonspecific binding sites were blocked with BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM21663(N-[4-(2,2,2-trifluoro-1-hydroxyethyl)phenyl]-N-(2,...)
Affinity DataIC50: 1.00E+4nM EC50:  1.00E+3nMpH: 8.0 T: 2°CAssay Description:Polylysine YiO imaging beads (Amersham, GE Healthcare) were coated with histidine-tagged WT PXR LBD. Nonspecific binding sites were blocked with BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM21669(N-(4-acetylphenyl)-N-(2,2,2-trifluoroethyl)benzene...)
Affinity DataIC50: 1.59E+3nM EC50:  1.00E+4nMpH: 8.0 T: 2°CAssay Description:Polylysine YiO imaging beads (Amersham, GE Healthcare) were coated with histidine-tagged WT PXR LBD. Nonspecific binding sites were blocked with BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM21668(N-[4-(1-hydroxyethyl)phenyl]-N-(2,2,2-trifluoroeth...)
Affinity DataIC50: 2.51E+3nM EC50:  1.00E+4nMpH: 8.0 T: 2°CAssay Description:Polylysine YiO imaging beads (Amersham, GE Healthcare) were coated with histidine-tagged WT PXR LBD. Nonspecific binding sites were blocked with BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM21667(N-[4-(hydroxymethyl)phenyl]-N-(2,2,2-trifluoroethy...)
Affinity DataIC50: 7.94E+3nM EC50:  1.00E+4nMpH: 8.0 T: 2°CAssay Description:Polylysine YiO imaging beads (Amersham, GE Healthcare) were coated with histidine-tagged WT PXR LBD. Nonspecific binding sites were blocked with BSA....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed