Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 2560
TargetMonocarboxylate transporter 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 21995BDBM21995(5-{[(4S)-4-hydroxy-1,2-oxazolidin-2-yl]carbonyl}-3...)
Affinity DataKi:  0.0900nM ΔG°:  -56.8kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2008
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 21992BDBM21992(5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-3-meth...)
Affinity DataKi:  0.310nM ΔG°:  -53.7kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2008
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 21996BDBM21996(5-{[(4S)-4-hydroxy-1,2-oxazolidin-2-yl]carbonyl}-3...)
Affinity DataKi:  0.430nM ΔG°:  -52.9kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2008
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 21994BDBM21994(5-{[(4S)-4-hydroxy-1,2-oxazolidin-2-yl]carbonyl}-3...)
Affinity DataKi:  0.520nM ΔG°:  -52.5kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2008
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 21987BDBM21987(6-[(6-fluoroquinolin-4-yl)methyl]-5-{[(3R)-3-hydro...)
Affinity DataKi:  0.810nM ΔG°:  -51.4kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2008
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 21998BDBM21998(6-[(3,5-dimethyl-1H-pyrazol-4-yl)methyl]-5-{[(4S)-...)
Affinity DataKi:  1.20nM ΔG°:  -50.4kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2008
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 21997BDBM21997(5-{[(4S)-4-hydroxy-1,2-oxazolidin-2-yl]carbonyl}-3...)
Affinity DataKi:  1.70nM ΔG°:  -49.6kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2008
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 21993BDBM21993(6-[(4,5-dichloro-2-methyl-1H-imidazol-1-yl)methyl]...)
Affinity DataKi:  3.20nM ΔG°:  -48.0kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2008
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 21985BDBM21985(5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-3-meth...)
Affinity DataKi:  4.80nM ΔG°:  -47.0kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2008
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 21991BDBM21991(5-{[(3R,4S)-3,4-dihydroxypyrrolidin-1-yl]carbonyl}...)
Affinity DataKi:  29nM ΔG°:  -42.6kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2008
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 21990BDBM21990(5-(azetidin-1-ylcarbonyl)-3-methyl-6-{[2-(methylam...)
Affinity DataKi:  59nM ΔG°:  -40.8kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2008
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 21988BDBM21988(N,N,3-trimethyl-2,4-dioxo-1-(propan-2-yl)-6-{[2-(t...)
Affinity DataKi:  117nM ΔG°:  -39.2kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2008
Entry Details Article
PubMed
TargetMonocarboxylate transporter 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 21989BDBM21989(3-{[3-methyl-2,4-dioxo-1-(propan-2-yl)-6-{[2-(trif...)
Affinity DataKi: >190nM ΔG°: >-38.0kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2008
Entry Details Article
PubMed