Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 2326
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois At Urbana-Champaign

LigandPNGBDBM19455(4-(3-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-5,7-bis(...)
Affinity DataKi:  7nM ΔG°:  -42.6kJ/mole EC50:  90nMpH: 7.5 T: 2°CAssay Description:Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois At Urbana-Champaign

LigandPNGBDBM19454(4-[2-(4-hydroxyphenyl)-5,7-bis(trifluoromethyl)pyr...)
Affinity DataKi:  26nM ΔG°:  -39.7kJ/mole EC50:  6.00E+3nMpH: 7.5 T: 2°CAssay Description:Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois At Urbana-Champaign

LigandPNGBDBM19456(4-(3-{4-[2-(dimethylamino)ethoxy]phenyl}-5,7-bis(t...)
Affinity DataKi:  47nM ΔG°:  -38.3kJ/mole EC50:  1.00E+3nMpH: 7.5 T: 2°CAssay Description:Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
University of Illinois At Urbana-Champaign

LigandPNGBDBM19454(4-[2-(4-hydroxyphenyl)-5,7-bis(trifluoromethyl)pyr...)
Affinity DataKi:  48nM ΔG°:  -38.3kJ/mole EC50:  600nMpH: 7.5 T: 2°CAssay Description:Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois At Urbana-Champaign

LigandPNGBDBM19453(4-[3-phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a...)
Affinity DataKi:  51nM ΔG°:  -38.1kJ/molepH: 7.5 T: 2°CAssay Description:Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
University of Illinois At Urbana-Champaign

LigandPNGBDBM19455(4-(3-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-5,7-bis(...)
Affinity DataKi:  71nM ΔG°:  -37.4kJ/mole EC50:  40nMpH: 7.5 T: 2°CAssay Description:Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
University of Illinois At Urbana-Champaign

LigandPNGBDBM19453(4-[3-phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a...)
Affinity DataKi:  122nM ΔG°:  -36.2kJ/molepH: 7.5 T: 2°CAssay Description:Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
University of Illinois At Urbana-Champaign

LigandPNGBDBM19452(4-[2-phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a...)
Affinity DataKi:  139nM ΔG°:  -35.9kJ/molepH: 7.5 T: 2°CAssay Description:Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
University of Illinois At Urbana-Champaign

LigandPNGBDBM19458(4-(2-{4-[2-(dimethylamino)ethoxy]phenyl}-5,7-bis(t...)
Affinity DataKi:  156nM ΔG°:  -35.6kJ/molepH: 7.5 T: 2°CAssay Description:Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
University of Illinois At Urbana-Champaign

LigandPNGBDBM19456(4-(3-{4-[2-(dimethylamino)ethoxy]phenyl}-5,7-bis(t...)
Affinity DataKi:  178nM ΔG°:  -35.3kJ/mole EC50:  250nMpH: 7.5 T: 2°CAssay Description:Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
University of Illinois At Urbana-Champaign

LigandPNGBDBM19457(4-(2-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-5,7-bis(...)
Affinity DataKi:  192nM ΔG°:  -35.1kJ/molepH: 7.5 T: 2°CAssay Description:Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois At Urbana-Champaign

LigandPNGBDBM19457(4-(2-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-5,7-bis(...)
Affinity DataKi:  266nM ΔG°:  -34.4kJ/molepH: 7.5 T: 2°CAssay Description:Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois At Urbana-Champaign

LigandPNGBDBM19458(4-(2-{4-[2-(dimethylamino)ethoxy]phenyl}-5,7-bis(t...)
Affinity DataKi:  408nM ΔG°:  -33.4kJ/molepH: 7.5 T: 2°CAssay Description:Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
University of Illinois At Urbana-Champaign

LigandPNGBDBM19451(2,3-bis(4-hydroxyphenyl)pyrazolo[1,5-a]pyrimidin-6...)
Affinity DataKi:  1.52E+3nM ΔG°:  -30.4kJ/molepH: 7.5 T: 2°CAssay Description:Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois At Urbana-Champaign

LigandPNGBDBM19452(4-[2-phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a...)
Affinity DataKi:  2.22E+3nM ΔG°:  -29.6kJ/molepH: 7.5 T: 2°CAssay Description:Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois At Urbana-Champaign

LigandPNGBDBM19451(2,3-bis(4-hydroxyphenyl)pyrazolo[1,5-a]pyrimidin-6...)
Affinity DataKi:  3.33E+3nM ΔG°:  -28.6kJ/molepH: 7.5 T: 2°CAssay Description:Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed