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Report error Found 112 Enz. Inhib. hit(s) with all data for entry = 50019407
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204396((3S,4S)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)met...)
Affinity DataIC50: <1nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204392((3R,4R)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)met...)
Affinity DataIC50:  1nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204402((3S,4S)-1-(but-2-ynyl)-N-hydroxy-4-(4-((2-methylqu...)
Affinity DataIC50:  1nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204403((3R,4R)-4-(4-((2,3-dihydro-1H-cyclopenta[b]quinoli...)
Affinity DataIC50:  1nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204408((3R,4R)-N-hydroxy-4-(4-((2-isopropylquinolin-4-yl)...)
Affinity DataIC50: <1nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204404((3S,4S)-tert-butyl 3-(hydroxycarbamoyl)-4-(4-((2-m...)
Affinity DataIC50: <1nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204391((3S,4S)-1-(butylsulfonyl)-N-hydroxy-4-(4-((2-methy...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204389((3R,4R)-4-(4-((2,3-dimethylquinolin-4-yl)methyl)be...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204385((3R,4R)-4-(4-((2-(dimethylamino)quinolin-4-yl)meth...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204412((3R,4R)-4-(4-((2-cyclopropylquinolin-4-yl)methyl)b...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204400((3R,4R)-4-(4-((2,3-dihydrofuro[2,3-b]quinolin-4-yl...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204388((3S,4S)-tert-butyl 3-(hydroxycarbamoyl)-4-(4-(2-me...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204413((3R,4R)-N-hydroxy-4-(4-((3-methylquinolin-4-yl)met...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204395((3S,4S)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)met...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204406((3R,4R)-N-hydroxy-4-(4-((2-morpholinoquinolin-4-yl...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204401((3S,4S)-N-hydroxy-1-isobutyl-4-(4-((2-methylquinol...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204393((3S,4S)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)met...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204390((3R,4R)-4-(4-((2-ethylquinolin-4-yl)methyl)benzami...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204409(CHEMBL401454 | N-((1R,2S)-2-(hydroxycarbamoyl)cycl...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204399((3R,4S)-N-hydroxy-4-(3-((2-methylquinolin-4-yl)met...)
Affinity DataIC50:  2nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204411((3R,4R)-N-hydroxy-4-(4-((2-(trifluoromethyl)quinol...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204398((3S,4S)-N-hydroxy-1-methyl-4-(4-((2-methylquinolin...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204394((3R,4R)-4-(4-((1,3-dihydrofuro[3,4-b]quinolin-9-yl...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204386((3S,4S)-methyl 3-(hydroxycarbamoyl)-4-(4-((2-methy...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204407((3S,4S)-N-hydroxy-4-(4-(2-methylquinolin-4-yloxy)b...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204397((3S,4S)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)met...)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204405((3S,4S)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)met...)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204410((3R,4R)-4-(4-((3-ethyl-2-methylquinolin-4-yl)methy...)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204386((3S,4S)-methyl 3-(hydroxycarbamoyl)-4-(4-((2-methy...)
Affinity DataIC50:  50nMAssay Description:Inhibition of TACE in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204396((3S,4S)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)met...)
Affinity DataIC50:  67nMAssay Description:Inhibition of TACE in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204403((3R,4R)-4-(4-((2,3-dihydro-1H-cyclopenta[b]quinoli...)
Affinity DataIC50:  72nMAssay Description:Inhibition of TACE in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204405((3S,4S)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)met...)
Affinity DataIC50:  75nMAssay Description:Inhibition of TACE in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204400((3R,4R)-4-(4-((2,3-dihydrofuro[2,3-b]quinolin-4-yl...)
Affinity DataIC50:  77nMAssay Description:Inhibition of TACE in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204390((3R,4R)-4-(4-((2-ethylquinolin-4-yl)methyl)benzami...)
Affinity DataIC50:  78nMAssay Description:Inhibition of TACE in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204389((3R,4R)-4-(4-((2,3-dimethylquinolin-4-yl)methyl)be...)
Affinity DataIC50:  85nMAssay Description:Inhibition of TACE in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204397((3S,4S)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)met...)
Affinity DataIC50:  86nMAssay Description:Inhibition of TACE in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204394((3R,4R)-4-(4-((1,3-dihydrofuro[3,4-b]quinolin-9-yl...)
Affinity DataIC50:  87nMAssay Description:Inhibition of TACE in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204395((3S,4S)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)met...)
Affinity DataIC50:  95nMAssay Description:Inhibition of TACE in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204404((3S,4S)-tert-butyl 3-(hydroxycarbamoyl)-4-(4-((2-m...)
Affinity DataIC50:  96nMAssay Description:Inhibition of TACE in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204398((3S,4S)-N-hydroxy-1-methyl-4-(4-((2-methylquinolin...)
Affinity DataIC50:  96nMAssay Description:Inhibition of TACE in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204387(CHEMBL234032 | N-(4-(2-(hydroxyamino)-2-oxoethyl)-...)
Affinity DataIC50:  97nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204413((3R,4R)-N-hydroxy-4-(4-((3-methylquinolin-4-yl)met...)
Affinity DataIC50:  98nMAssay Description:Inhibition of TACE in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204402((3S,4S)-1-(but-2-ynyl)-N-hydroxy-4-(4-((2-methylqu...)
Affinity DataIC50:  110nMAssay Description:Inhibition of TACE in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204391((3S,4S)-1-(butylsulfonyl)-N-hydroxy-4-(4-((2-methy...)
Affinity DataIC50:  120nMAssay Description:Inhibition of TACE in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204392((3R,4R)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)met...)
Affinity DataIC50:  130nMAssay Description:Inhibition of TACE in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204399((3R,4S)-N-hydroxy-4-(3-((2-methylquinolin-4-yl)met...)
Affinity DataIC50:  130nMAssay Description:Inhibition of TACE in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204401((3S,4S)-N-hydroxy-1-isobutyl-4-(4-((2-methylquinol...)
Affinity DataIC50:  220nMAssay Description:Inhibition of TACE in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204412((3R,4R)-4-(4-((2-cyclopropylquinolin-4-yl)methyl)b...)
Affinity DataIC50:  230nMAssay Description:Inhibition of TACE in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204411((3R,4R)-N-hydroxy-4-(4-((2-(trifluoromethyl)quinol...)
Affinity DataIC50:  260nMAssay Description:Inhibition of TACE in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204408((3R,4R)-N-hydroxy-4-(4-((2-isopropylquinolin-4-yl)...)
Affinity DataIC50:  420nMAssay Description:Inhibition of TACE in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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