Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50025161 Sort by
TargetFocal adhesion kinase 1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50269948(PF-228 | 6-(4-(3-(methylsulfonyl)benzylamino)-5-(t...)
Affinity DataIC50: 4nMAssay Description:Inhibition of FAKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFocal adhesion kinase 1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50269948(PF-228 | 6-(4-(3-(methylsulfonyl)benzylamino)-5-(t...)
Affinity DataIC50: 11nMAssay Description:Inhibition of FAK Tyr397 phosphorylation in human A431 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFocal adhesion kinase 1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50269948(PF-228 | 6-(4-(3-(methylsulfonyl)benzylamino)-5-(t...)
Affinity DataIC50: 30nMAssay Description:Inhibition of FAK Tyr397 phosphorylation in human FG cells after 60 mins by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFocal adhesion kinase 1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50269948(PF-228 | 6-(4-(3-(methylsulfonyl)benzylamino)-5-(t...)
Affinity DataIC50: 50nMAssay Description:Inhibition of FAK Tyr397 phosphorylation in human SKOV3 cells after 60 mins by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFocal adhesion kinase 1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50269948(PF-228 | 6-(4-(3-(methylsulfonyl)benzylamino)-5-(t...)
Affinity DataIC50: 100nMAssay Description:Inhibition of FAK Tyr397 phosphorylation in human PC3 cells after 60 mins by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 7(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50269948(PF-228 | 6-(4-(3-(methylsulfonyl)benzylamino)-5-(t...)
Affinity DataIC50: 197nMAssay Description:Inhibition of human CDK7/cyclinH/MAT1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFocal adhesion kinase 1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50269948(PF-228 | 6-(4-(3-(methylsulfonyl)benzylamino)-5-(t...)
Affinity DataIC50: 300nMAssay Description:Inhibition of FAK Tyr397 phosphorylation in human L3.6pl cells after 60 mins by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 1(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50269948(PF-228 | 6-(4-(3-(methylsulfonyl)benzylamino)-5-(t...)
Affinity DataIC50: 486nMAssay Description:Inhibition of human CDK1/cyclinBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50269948(PF-228 | 6-(4-(3-(methylsulfonyl)benzylamino)-5-(t...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Pyk2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50269948(PF-228 | 6-(4-(3-(methylsulfonyl)benzylamino)-5-(t...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed