Compile Data Set for Download or QSAR
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Found 27 Enz. Inhib. hit(s) with all data for entry = 50037884
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146518((3R,3aS)-3-{4-[3-(4-Fluoro-phenyl)-2-methyl-allyl]...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]rawolscine from human cloned adrenergic alpha-2B receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146518((3R,3aS)-3-{4-[3-(4-Fluoro-phenyl)-2-methyl-allyl]...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]paroxetine from human cloned 5HTT receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146518((3R,3aS)-3-{4-[3-(4-Fluoro-phenyl)-2-methyl-allyl]...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]paroxetine from human cloned 5HTT receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50209685(CHEMBL226636 | cis-(+)-7,8-dimethoxy-3-[4-(3-(4-fl...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]paroxetine from human cloned 5HTT receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50209685(CHEMBL226636 | cis-(+)-7,8-dimethoxy-3-[4-(3-(4-fl...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]paroxetine from human cloned 5HTT receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50209684(CHEMBL390718 | cis-(+)-7,8-dimethoxy-3-[4-(2-methy...)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]rawolscine from human cloned adrenergic alpha2A receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50209684(CHEMBL390718 | cis-(+)-7,8-dimethoxy-3-[4-(2-methy...)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]rawolscine from human cloned adrenergic alpha2A receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50209684(CHEMBL390718 | cis-(+)-7,8-dimethoxy-3-[4-(2-methy...)
Affinity DataKi:  8.30nMAssay Description:Displacement of [3H]rawolscine from human cloned adrenergic Alpha-2C receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50209684(CHEMBL390718 | cis-(+)-7,8-dimethoxy-3-[4-(2-methy...)
Affinity DataKi:  8.30nMAssay Description:Displacement of [3H]rawolscine from human cloned adrenergic Alpha-2C receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50209684(CHEMBL390718 | cis-(+)-7,8-dimethoxy-3-[4-(2-methy...)
Affinity DataKi:  8.90nMAssay Description:Displacement of [3H]paroxetine from human cloned 5HTT receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50209684(CHEMBL390718 | cis-(+)-7,8-dimethoxy-3-[4-(2-methy...)
Affinity DataKi:  8.90nMAssay Description:Displacement of [3H]paroxetine from human cloned 5HTT receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146518((3R,3aS)-3-{4-[3-(4-Fluoro-phenyl)-2-methyl-allyl]...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]rawolscine from human cloned adrenergic Alpha-2C receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146518((3R,3aS)-3-{4-[3-(4-Fluoro-phenyl)-2-methyl-allyl]...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]rawolscine from human cloned adrenergic Alpha-2C receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50209684(CHEMBL390718 | cis-(+)-7,8-dimethoxy-3-[4-(2-methy...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]rawolscine from human cloned adrenergic alpha-2B receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146518((3R,3aS)-3-{4-[3-(4-Fluoro-phenyl)-2-methyl-allyl]...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]rawolscine from human cloned adrenergic alpha2A receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146518((3R,3aS)-3-{4-[3-(4-Fluoro-phenyl)-2-methyl-allyl]...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]rawolscine from human cloned adrenergic alpha2A receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146518((3R,3aS)-3-{4-[3-(4-Fluoro-phenyl)-2-methyl-allyl]...)
Affinity DataKi:  70nMAssay Description:Displacement of [3H]nisoxetine from rat NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50209685(CHEMBL226636 | cis-(+)-7,8-dimethoxy-3-[4-(3-(4-fl...)
Affinity DataKi:  72nMAssay Description:Displacement of [3H]rawolscine from human cloned adrenergic Alpha-2C receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50209685(CHEMBL226636 | cis-(+)-7,8-dimethoxy-3-[4-(3-(4-fl...)
Affinity DataKi:  72nMAssay Description:Displacement of [3H]rawolscine from human cloned adrenergic Alpha-2C receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146518((3R,3aS)-3-{4-[3-(4-Fluoro-phenyl)-2-methyl-allyl]...)
Affinity DataKi:  74nMAssay Description:Displacement of [3H]pyrilamine from human cloned histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50209685(CHEMBL226636 | cis-(+)-7,8-dimethoxy-3-[4-(3-(4-fl...)
Affinity DataKi:  117nMAssay Description:Displacement of [3H]rawolscine from human cloned adrenergic alpha2A receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50209685(CHEMBL226636 | cis-(+)-7,8-dimethoxy-3-[4-(3-(4-fl...)
Affinity DataKi:  117nMAssay Description:Displacement of [3H]rawolscine from human cloned adrenergic alpha2A receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146518((3R,3aS)-3-{4-[3-(4-Fluoro-phenyl)-2-methyl-allyl]...)
Affinity DataKi:  125nMAssay Description:Displacement of [3H]prazosin from human cloned alpha-1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50209685(CHEMBL226636 | cis-(+)-7,8-dimethoxy-3-[4-(3-(4-fl...)
Affinity DataKi:  162nMAssay Description:Displacement of [3H]rawolscine from human cloned adrenergic alpha-2B receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146518((3R,3aS)-3-{4-[3-(4-Fluoro-phenyl)-2-methyl-allyl]...)
Affinity DataKi:  310nMAssay Description:Displacement of [3H]substance P from human cloned NK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146518((3R,3aS)-3-{4-[3-(4-Fluoro-phenyl)-2-methyl-allyl]...)
Affinity DataKi:  375nMAssay Description:Displacement of [125I]iodosulpiride from human cloned dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146518((3R,3aS)-3-{4-[3-(4-Fluoro-phenyl)-2-methyl-allyl]...)
Affinity DataKi:  583nMAssay Description:Displacement of [3H]WIN-35428 from rat DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed