Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50020143
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210717BDBM50210717(N1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-difluoro...)
Affinity DataIC50: 2nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210721BDBM50210721(N1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-difluoro...)
Affinity DataIC50: 5nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210709BDBM50210709(N~3~-{(1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-3-[...)
Affinity DataIC50: 11nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210719BDBM50210719(3-(((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-p...)
Affinity DataIC50: 30nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210715BDBM50210715(N1-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-p...)
Affinity DataIC50: 70nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210718BDBM50210718(N1-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-p...)
Affinity DataIC50: 90nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210722BDBM50210722(N1-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-p...)
Affinity DataIC50: 100nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210714BDBM50210714(N1-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-p...)
Affinity DataIC50: 100nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210713BDBM50210713(ethyl 3-(((2S,3R)-4-(3-methoxybenzylamino)-3-hydro...)
Affinity DataIC50: 132nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210717BDBM50210717(N1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-difluoro...)
Affinity DataIC50: 150nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210712BDBM50210712(N1-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-p...)
Affinity DataIC50: 250nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210720BDBM50210720(N1-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-(...)
Affinity DataIC50: 300nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210710BDBM50210710(N1-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-p...)
Affinity DataIC50: 360nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210714BDBM50210714(N1-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-p...)
Affinity DataIC50: 450nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210710BDBM50210710(N1-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-p...)
Affinity DataIC50: 570nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210718BDBM50210718(N1-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-p...)
Affinity DataIC50: 660nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210711BDBM50210711(N1-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-p...)
Affinity DataIC50: 770nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210713BDBM50210713(ethyl 3-(((2S,3R)-4-(3-methoxybenzylamino)-3-hydro...)
Affinity DataIC50: 866nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210721BDBM50210721(N1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-difluoro...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210716BDBM50210716(N1-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-p...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210709BDBM50210709(N~3~-{(1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-3-[...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210722BDBM50210722(N1-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-p...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210712BDBM50210712(N1-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-p...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210719BDBM50210719(3-(((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-p...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210715BDBM50210715(N1-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-p...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210720BDBM50210720(N1-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-(...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210711BDBM50210711(N1-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-p...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210716BDBM50210716(N1-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-p...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed