Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 2332
TargetCathepsin S(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19488(2-{2-[2,3-difluoro-4-(2-methylpropyl)phenyl]phenox...)
Affinity DataKi:  9.60nM ΔG°:  -47.6kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19487(2-[2-(2,3-difluoro-4-propylphenyl)phenoxy]acetalde...)
Affinity DataKi:  48.7nM ΔG°:  -43.4kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19486(2-[2-(2,3,4-trifluorophenyl)phenoxy]acetaldehyde |...)
Affinity DataKi:  490nM ΔG°:  -37.5kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19488(2-{2-[2,3-difluoro-4-(2-methylpropyl)phenyl]phenox...)
Affinity DataKi:  1.24E+3nM ΔG°:  -35.1kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19487(2-[2-(2,3-difluoro-4-propylphenyl)phenoxy]acetalde...)
Affinity DataKi:  1.28E+3nM ΔG°:  -35.0kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19486(2-[2-(2,3,4-trifluorophenyl)phenoxy]acetaldehyde |...)
Affinity DataKi:  1.51E+3nM ΔG°:  -34.6kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19486(2-[2-(2,3,4-trifluorophenyl)phenoxy]acetaldehyde |...)
Affinity DataKi:  1.54E+3nM ΔG°:  -34.5kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19487(2-[2-(2,3-difluoro-4-propylphenyl)phenoxy]acetalde...)
Affinity DataKi:  5.19E+3nM ΔG°:  -31.4kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19487(2-[2-(2,3-difluoro-4-propylphenyl)phenoxy]acetalde...)
Affinity DataKi: >1.50E+4nM ΔG°: >-28.6kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19486(2-[2-(2,3,4-trifluorophenyl)phenoxy]acetaldehyde |...)
Affinity DataKi: >1.50E+4nM ΔG°: >-28.6kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19488(2-{2-[2,3-difluoro-4-(2-methylpropyl)phenyl]phenox...)
Affinity DataKi: >1.50E+4nM ΔG°: >-28.6kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University of California Berkeley

LigandPNGBDBM19488(2-{2-[2,3-difluoro-4-(2-methylpropyl)phenyl]phenox...)
Affinity DataKi: >1.50E+4nM ΔG°: >-28.6kJ/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed