Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50020337
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212688BDBM50212688(2-(3,5-dimethyl-benzyl)-5-trifluoromethoxy-2,3-dih...)
Affinity DataKi:  2nMAssay Description:Binding affinity to NMDA NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212685BDBM50212685(2-benzofuran-7-ylmethyl-5-trifluoromethoxy-2,3-dih...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity to NMDA NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212684BDBM50212684(2-(2-methoxy-benzyl)-5-trifluoromethoxy-2,3-dihydr...)
Affinity DataKi:  3.60nMAssay Description:Binding affinity to NMDA NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212684BDBM50212684(2-(2-methoxy-benzyl)-5-trifluoromethoxy-2,3-dihydr...)
Affinity DataIC50: 5.90nMAssay Description:Antagonist activity at NMDA NR2B receptor assessed as calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212687BDBM50212687(2-(3-chloro-benzyl)-5-trifluoromethoxy-2,3-dihydro...)
Affinity DataKi:  8nMAssay Description:Binding affinity to NMDA NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212685BDBM50212685(2-benzofuran-7-ylmethyl-5-trifluoromethoxy-2,3-dih...)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at NMDA NR2B receptor assessed as calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212688BDBM50212688(2-(3,5-dimethyl-benzyl)-5-trifluoromethoxy-2,3-dih...)
Affinity DataIC50: 39nMAssay Description:Antagonist activity at NMDA NR2B receptor assessed as calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50124907BDBM50124907(4-trifluoromethoxy-N-(2-trifluoromethyl-benzyl)-be...)
Affinity DataIC50: 47nMAssay Description:Antagonist activity at NMDA NR2B receptor assessed as calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212687BDBM50212687(2-(3-chloro-benzyl)-5-trifluoromethoxy-2,3-dihydro...)
Affinity DataIC50: 49nMAssay Description:Antagonist activity at NMDA NR2B receptor assessed as calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212681BDBM50212681(2-(3-chloro-4-(trifluoromethoxy)phenyl)-5-(3-chlor...)
Affinity DataKi:  66nMAssay Description:Binding affinity to NMDA NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50124907BDBM50124907(4-trifluoromethoxy-N-(2-trifluoromethyl-benzyl)-be...)
Affinity DataKi:  72nMAssay Description:Binding affinity to NMDA NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212682BDBM50212682(2-(3-chloro-4-(trifluoromethoxy)phenyl)-5-(2-metho...)
Affinity DataKi:  75nMAssay Description:Binding affinity to NMDA NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212682BDBM50212682(2-(3-chloro-4-(trifluoromethoxy)phenyl)-5-(2-metho...)
Affinity DataIC50: 108nMAssay Description:Antagonist activity at NMDA NR2B receptor assessed as calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212680BDBM50212680(2-(3-chloro-4-(trifluoromethoxy)phenyl)-5-(3,5-dic...)
Affinity DataKi:  223nMAssay Description:Binding affinity to NMDA NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212681BDBM50212681(2-(3-chloro-4-(trifluoromethoxy)phenyl)-5-(3-chlor...)
Affinity DataIC50: 266nMAssay Description:Antagonist activity at NMDA NR2B receptor assessed as calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212683BDBM50212683(5-(3-chlorophenyl)-2-(4-(trifluoromethoxy)phenyl)-...)
Affinity DataKi:  296nMAssay Description:Binding affinity to NMDA NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212690BDBM50212690(2-(3-chloro-4-(trifluoromethoxy)phenyl)-5-(2-(trif...)
Affinity DataKi:  353nMAssay Description:Binding affinity to NMDA NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212679BDBM50212679(2-(3-chloro-4-(trifluoromethoxy)phenyl)-5-(2-(trif...)
Affinity DataKi:  505nMAssay Description:Binding affinity to NMDA NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212690BDBM50212690(2-(3-chloro-4-(trifluoromethoxy)phenyl)-5-(2-(trif...)
Affinity DataIC50: 1.27E+3nMAssay Description:Antagonist activity at NMDA NR2B receptor assessed as calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212683BDBM50212683(5-(3-chlorophenyl)-2-(4-(trifluoromethoxy)phenyl)-...)
Affinity DataIC50: 1.98E+3nMAssay Description:Antagonist activity at NMDA NR2B receptor assessed as calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212679BDBM50212679(2-(3-chloro-4-(trifluoromethoxy)phenyl)-5-(2-(trif...)
Affinity DataIC50: 3.48E+3nMAssay Description:Antagonist activity at NMDA NR2B receptor assessed as calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212680BDBM50212680(2-(3-chloro-4-(trifluoromethoxy)phenyl)-5-(3,5-dic...)
Affinity DataIC50: 3.67E+3nMAssay Description:Antagonist activity at NMDA NR2B receptor assessed as calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212689BDBM50212689((Z)-7-phenyl-2-(4-(trifluoromethoxy)phenyl)-4,5,6,...)
Affinity DataKi:  4.20E+3nMAssay Description:Binding affinity to NMDA NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212686BDBM50212686(6-phenyl-2-(4-(trifluoromethoxy)phenyl)-1,4,5,6-te...)
Affinity DataKi:  7.35E+3nMAssay Description:Binding affinity to NMDA NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed