Compile Data Set for Download or QSAR
maximum 50k data
Found 78 Enz. Inhib. hit(s) with all data for entry = 50020350
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212764(CHEMBL233338 | N-(1-(3-aminopropyl)-5-(N-methylcyc...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212789(1-(5-amino-5-oxopentyl)-N-cyclohexyl-N-methyl-2-(t...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212761(1-(3-amino-3-oxopropyl)-N-cyclohexyl-N-methyl-2-(o...)
Affinity DataIC50:  62nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212770(1-(3-amino-3-oxopropyl)-N-cyclohexyl-N-methyl-2-(n...)
Affinity DataIC50:  69nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212760(1-(3-amino-3-oxopropyl)-N-cyclohexyl-N-methyl-2-(4...)
Affinity DataIC50:  76nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212788(1-(3-amino-3-oxopropyl)-2-(4-bromobenzamido)-N-cyc...)
Affinity DataIC50:  81nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212776(CHEMBL233365 | N-cyclohexyl-1-(3-hydroxypropyl)-N-...)
Affinity DataIC50:  92nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212764(CHEMBL233338 | N-(1-(3-aminopropyl)-5-(N-methylcyc...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human ITK in presence of 3 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212795(1-(3-amino-3-oxopropyl)-N-cyclohexyl-2-(3-fluorobe...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212778(1-(3-amino-3-oxopropyl)-N-cyclohexyl-N-methyl-2-(t...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212783(1-(4-amino-4-oxobutyl)-N-cyclohexyl-N-methyl-2-(th...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212773(CHEMBL391934 | N-cyclohexyl-N-methyl-1-(3-(methyla...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212785(CHEMBL233169 | N-cyclohexyl-1-(2-hydroxyethyl)-N-m...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212771(1-(3-amino-3-oxopropyl)-2-(4-cyanobenzamido)-N-cyc...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212779(CHEMBL232579 | ethyl 3-(5-(cyclohexyl(methyl)carba...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212772(CHEMBL232381 | N-allyl-1-(3-amino-3-oxopropyl)-2-(...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212794(1-(3-amino-3-oxopropyl)-N-cyclohexyl-2-(4-fluorobe...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212781(1-(3-amino-3-oxopropyl)-2-(4-bromobenzamido)-N-cyc...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212764(CHEMBL233338 | N-(1-(3-aminopropyl)-5-(N-methylcyc...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human ITK in presence of 20 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212767(1-(3-amino-3-oxopropyl)-2-benzamido-N-methyl-N-phe...)
Affinity DataIC50:  330nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212777(1-(3-amino-3-oxopropyl)-2-benzamido-N-cyclohexyl-N...)
Affinity DataIC50:  370nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212774(1-(3-amino-3-oxopropyl)-2-benzamido-N-cyclohexyl-N...)
Affinity DataIC50:  390nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212763(3-(3-aminopropyl)-N-cyclohexyl-N-methyl-2-(thiophe...)
Affinity DataIC50:  710nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212790(CHEMBL232157 | N-allyl-1-(3-amino-3-oxopropyl)-2-b...)
Affinity DataIC50:  730nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212766(CHEMBL232966 | N-cyclohexyl-N-methyl-1-propyl-2-(t...)
Affinity DataIC50:  760nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212787(1-(3-aminopropyl)-N-cyclohexyl-N-methyl-2-(thiophe...)
Affinity DataIC50:  950nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212775(1-(3-amino-3-oxopropyl)-N-cyclohexyl-2-(4-methoxyb...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212788(1-(3-amino-3-oxopropyl)-2-(4-bromobenzamido)-N-cyc...)
Affinity DataIC50:  1.20E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212781(1-(3-amino-3-oxopropyl)-2-(4-bromobenzamido)-N-cyc...)
Affinity DataIC50:  1.20E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212772(CHEMBL232381 | N-allyl-1-(3-amino-3-oxopropyl)-2-(...)
Affinity DataIC50:  1.20E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212769(CHEMBL233168 | N-cyclohexyl-N-methyl-1-phenethyl-2...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212764(CHEMBL233338 | N-(1-(3-aminopropyl)-5-(N-methylcyc...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of TXKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212780(CHEMBL231708 | N-(1-(3-aminopropyl)-1H-benzo[d]imi...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212766(CHEMBL232966 | N-cyclohexyl-N-methyl-1-propyl-2-(t...)
Affinity DataIC50:  1.60E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212764(CHEMBL233338 | N-(1-(3-aminopropyl)-5-(N-methylcyc...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human ITK in presence of 100 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212765(CHEMBL400228 | N-(1-(3-aminopropyl)-5-(cyclohexane...)
Affinity DataIC50:  1.70E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212769(CHEMBL233168 | N-cyclohexyl-N-methyl-1-phenethyl-2...)
Affinity DataIC50:  1.80E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212776(CHEMBL233365 | N-cyclohexyl-1-(3-hydroxypropyl)-N-...)
Affinity DataIC50:  2.00E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212764(CHEMBL233338 | N-(1-(3-aminopropyl)-5-(N-methylcyc...)
Affinity DataIC50:  2.40E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212765(CHEMBL400228 | N-(1-(3-aminopropyl)-5-(cyclohexane...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212767(1-(3-amino-3-oxopropyl)-2-benzamido-N-methyl-N-phe...)
Affinity DataIC50:  2.60E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212792(1-(3-amino-3-oxopropyl)-N-cyclohexyl-N-methyl-2-(2...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212778(1-(3-amino-3-oxopropyl)-N-cyclohexyl-N-methyl-2-(t...)
Affinity DataIC50:  2.70E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212770(1-(3-amino-3-oxopropyl)-N-cyclohexyl-N-methyl-2-(n...)
Affinity DataIC50:  2.70E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212789(1-(5-amino-5-oxopentyl)-N-cyclohexyl-N-methyl-2-(t...)
Affinity DataIC50:  3.10E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212794(1-(3-amino-3-oxopropyl)-N-cyclohexyl-2-(4-fluorobe...)
Affinity DataIC50:  4.10E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212761(1-(3-amino-3-oxopropyl)-N-cyclohexyl-N-methyl-2-(o...)
Affinity DataIC50:  4.10E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212783(1-(4-amino-4-oxobutyl)-N-cyclohexyl-N-methyl-2-(th...)
Affinity DataIC50:  4.60E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212785(CHEMBL233169 | N-cyclohexyl-1-(2-hydroxyethyl)-N-m...)
Affinity DataIC50:  4.60E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212782(CHEMBL232965 | N-cyclohexyl-N-methyl-2-(thiophene-...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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