Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50020427
TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCannabinoid receptor 2(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]CP55940 from mouse CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 1(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]CP55940 from mouse CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213617((Z)-methyl 2-(2-isopropylphenylimino)-5,5-dimethyl...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213617((Z)-methyl 2-(2-isopropylphenylimino)-5,5-dimethyl...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]CP55940 from mouse CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 1(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213619((Z)-methyl 2-(2-methoxyphenylimino)-5,5-dimethyl-1...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213634((Z)-methyl 2-(4-isopropylphenylimino)-5,5-dimethyl...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213637((Z)-methyl 2-(3-isopropylphenylimino)-5,5-dimethyl...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213618((Z)-ethyl 2-(2-isopropylphenylimino)-5,5-dimethyl-...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213628((Z)-S-ethyl 2-(2-isopropylphenylimino)-5,5-dimethy...)
Affinity DataKi:  48nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213648((Z)-methyl 2-(2-ethylphenylimino)-5,5-dimethyl-1,3...)
Affinity DataKi:  54nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213627((Z)-methyl 5,5-dimethyl-2-(2-propylphenylimino)-1,...)
Affinity DataKi:  57nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213616((Z)-methyl 2-(2-ethoxyphenylimino)-5,5-dimethyl-1,...)
Affinity DataKi:  84nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213646((Z)-methyl 2-(2-isopropylphenylimino)-5-methyl-1,3...)
Affinity DataKi:  98nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213647((Z)-propyl 2-(2-isopropylphenylimino)-5,5-dimethyl...)
Affinity DataKi:  119nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213629((Z)-methyl 5,5-dimethyl-2-(2-(trifluoromethyl)phen...)
Affinity DataKi:  141nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213615((Z)-ethyl 2-(2-isopropylphenylimino)-5,5-dimethyl-...)
Affinity DataKi:  187nMAssay Description:Displacement of [3H]CP55940 from mouse CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213622((Z)-methyl 5,5-dimethyl-2-(o-tolylimino)-1,3-thiaz...)
Affinity DataKi:  202nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213644((Z)-O-ethyl 2-(2-isopropylphenylimino)-5,5-dimethy...)
Affinity DataKi:  230nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213626((Z)-methyl 2-(2-fluorophenylimino)-5,5-dimethyl-1,...)
Affinity DataKi:  252nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213620((Z)-isopropyl 2-(2-isopropylphenylimino)-5,5-dimet...)
Affinity DataKi:  275nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213625((Z)-methyl 2-(2-tert-butylphenylimino)-5,5-dimethy...)
Affinity DataKi:  313nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213631((Z)-methyl 5,5-dimethyl-2-(phenylimino)-1,3-thiazi...)
Affinity DataKi:  316nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213632((Z)-methyl 2-(2-bromophenylimino)-5,5-dimethyl-1,3...)
Affinity DataKi:  371nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213615((Z)-ethyl 2-(2-isopropylphenylimino)-5,5-dimethyl-...)
Affinity DataKi:  428nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213645((Z)-methyl 2-(2-chlorophenylimino)-5,5-dimethyl-1,...)
Affinity DataKi:  722nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213640((Z)-N-(5,5-dimethyl-3-propyl-1,3-thiazinan-2-ylide...)
Affinity DataKi:  915nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213633(2-[(Z)-biphenyl-2-ylimino]-5,5-dimethyl-[1,3]thiaz...)
Affinity DataKi:  989nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213621((Z)-N-(3-benzyl-5,5-dimethyl-1,3-thiazinan-2-ylide...)
Affinity DataKi:  1.36E+3nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213635((Z)-methyl 2-(2-isopropylphenylimino)-1,3-thiazina...)
Affinity DataKi:  1.58E+3nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 1(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213617((Z)-methyl 2-(2-isopropylphenylimino)-5,5-dimethyl...)
Affinity DataKi:  2.02E+3nMAssay Description:Displacement of [3H]CP55940 from mouse CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213623((Z)-1-(2-(2-isopropylphenylimino)-5,5-dimethyl-1,3...)
Affinity DataKi:  2.09E+3nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213641((Z)-methyl 5,5-dimethyl-2-(2-phenoxyphenylimino)-1...)
Affinity DataKi:  2.92E+3nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213624((Z)-N-(3-ethyl-5,5-dimethyl-1,3-thiazinan-2-yliden...)
Affinity DataKi:  4.88E+3nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213642((Z)-methyl 2-(2-isopropylphenylimino)-4-methyl-1,3...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213639((Z)-methyl 2-(2-isopropylphenylimino)-6-methyl-1,3...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213638((Z)-methyl 2-(2,6-dimethylphenylimino)-5,5-dimethy...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213636((Z)-N-ethyl-2-(2-isopropylphenylimino)-5,5-dimethy...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 1(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213615((Z)-ethyl 2-(2-isopropylphenylimino)-5,5-dimethyl-...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213630((Z)-N-(5,5-dimethyl-1,3-thiazinan-2-ylidene)-2-iso...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 1(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213617((Z)-methyl 2-(2-isopropylphenylimino)-5,5-dimethyl...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213643((Z)-N-ethyl-2-(2-isopropylphenylimino)-5,5-dimethy...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 1(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213615((Z)-ethyl 2-(2-isopropylphenylimino)-5,5-dimethyl-...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]CP55940 from mouse CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataIC50:  1.10nMAssay Description:Agonist activity at human CB2 in CHO cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213617((Z)-methyl 2-(2-isopropylphenylimino)-5,5-dimethyl...)
Affinity DataIC50:  6.10nMAssay Description:Agonist activity at human CB2 in CHO cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 1(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataIC50:  17nMAssay Description:Agonist activity at human CB1 in CHO cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213615((Z)-ethyl 2-(2-isopropylphenylimino)-5,5-dimethyl-...)
Affinity DataIC50:  322nMAssay Description:Agonist activity at human CB2 in CHO cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 1(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213615((Z)-ethyl 2-(2-isopropylphenylimino)-5,5-dimethyl-...)
Affinity DataIC50: >5.00E+3nMAssay Description:Agonist activity at human CB1 in CHO cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 1(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50213617((Z)-methyl 2-(2-isopropylphenylimino)-5,5-dimethyl...)
Affinity DataIC50: >5.00E+3nMAssay Description:Agonist activity at human CB1 in CHO cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed