Compile Data Set for Download or QSAR
maximum 50k data
Found 73 Enz. Inhib. hit(s) with all data for entry = 2061
LigandPNGBDBM15131(5-indazolyl pyridine 3 | 5-{5-[(2S)-2-amino-3-(1H-...)
Affinity DataIC50:  0.160nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16531((3Z)-5-(5-{[(2S)-2-amino-3-(1H-indol-3-yl)propyl]o...)
Affinity DataIC50:  0.170nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16532((2S)-1-(1H-indol-3-yl)-3-{[5-(3-methyl-1H-pyrazolo...)
Affinity DataIC50:  0.340nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16587((2S)-1-{[5-(3-methyl-1H-pyrazolo[3,4-c]pyridin-5-y...)
Affinity DataIC50:  0.600nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16548((2S)-1-(3-iodophenyl)-3-{[5-(3-methyl-1H-indazol-5...)
Affinity DataIC50:  0.900nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16564((2S)-1-{[5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl]...)
Affinity DataIC50:  1.20nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16569((2S)-1-[6-fluoro-3-(trifluoromethyl)phenyl]-3-{[5-...)
Affinity DataIC50:  1.20nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16555((2S)-1-(4-bromo-3-fluorophenyl)-3-{[5-(3-methyl-1H...)
Affinity DataIC50:  1.30nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16535((3E)-5-{5-[(2S)-2-amino-3-phenylpropoxy]pyridin-3-...)
Affinity DataIC50:  1.40nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16567((2S)-1-[4-fluoro-3-(trifluoromethyl)phenyl]-3-{[5-...)
Affinity DataIC50:  1.80nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16552((2S)-1-(3,4-dichlorophenyl)-3-{[5-(3-methyl-1H-ind...)
Affinity DataIC50:  1.80nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15067((2S)-1-(1H-indol-3-yl)-3-(5-isoquinolin-6-ylpyridi...)
Affinity DataIC50:  2nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16546((2S)-1-(3-bromophenyl)-3-{[5-(3-methyl-1H-indazol-...)
Affinity DataIC50:  2.10nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16561((2S)-1-(3-fluoro-4-methylphenyl)-3-{[5-(3-methyl-1...)
Affinity DataIC50:  2.40nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16558((2S)-1-(3-methyl-4-bromophenyl)-3-{[5-(3-methyl-1H...)
Affinity DataIC50:  2.5nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16586((2S)-1-{[5-(3-chloro-1H-pyrazolo[3,4-c]pyridin-5-y...)
Affinity DataIC50:  2.90nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16549((2S)-1-(3-chloro-4-fluorophenyl)-3-{[5-(3-methyl-1...)
Affinity DataIC50:  3.10nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16570((2S)-1-[3-fluoro-4-(trifluoromethyl)phenyl]-3-{[5-...)
Affinity DataIC50:  3.10nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16573((2S)-1-{[5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl]...)
Affinity DataIC50:  3.30nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16550((2S)-1-(3-fluoro-4-chlorophenyl)-3-{[5-(3-methyl-1...)
Affinity DataIC50:  3.60nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16557((2S)-1-(5-fluoro-2-methylphenyl)-3-{[5-(3-methyl-1...)
Affinity DataIC50:  3.90nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Abbott Laboratories

LigandPNGBDBM16564((2S)-1-{[5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl]...)
Affinity DataIC50:  5nMAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16588((2S)-1-(2,3-difluorophenyl)-3-{[5-(3-methyl-1H-pyr...)
Affinity DataIC50:  5nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16547((2S)-1-(4-bromophenyl)-3-{[5-(3-methyl-1H-indazol-...)
Affinity DataIC50:  5nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16551((2S)-1-(2,3-dichlorophenyl)-3-{[5-(3-methyl-1H-ind...)
Affinity DataIC50:  5.60nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16543((2S)-1-(3-chlorophenyl)-3-{[5-(3-methyl-1H-indazol...)
Affinity DataIC50:  5.90nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16560((2S)-1-(2-methyl-4-fluorophenyl)-3-{[5-(3-methyl-1...)
Affinity DataIC50:  6nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Abbott Laboratories

LigandPNGBDBM15131(5-indazolyl pyridine 3 | 5-{5-[(2S)-2-amino-3-(1H-...)
Affinity DataIC50:  6nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
LigandPNGBDBM16581(5-{5-[(2S)-2-amino-3-[3-(piperidin-4-ylmethoxy)phe...)
Affinity DataIC50:  6.80nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Abbott Laboratories

LigandPNGBDBM16588((2S)-1-(2,3-difluorophenyl)-3-{[5-(3-methyl-1H-pyr...)
Affinity DataIC50:  7nMAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16585((2S)-1-{[5-(1H-pyrazolo[3,4-c]pyridin-5-yl)pyridin...)
Affinity DataIC50:  7.20nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16563((2S)-1-(5-fluoro-2-methoxyphenyl)-3-{[5-(3-methyl-...)
Affinity DataIC50:  7.70nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16536((2S)-1-(3-fluorophenyl)-3-{[5-(3-methyl-1H-indazol...)
Affinity DataIC50:  8.40nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16537((2S)-1-(2,3-difluorophenyl)-3-{[5-(3-methyl-1H-ind...)
Affinity DataIC50:  8.5nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Abbott Laboratories

LigandPNGBDBM16537((2S)-1-(2,3-difluorophenyl)-3-{[5-(3-methyl-1H-ind...)
Affinity DataIC50:  9nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16554((2S)-1-(4-bromo-2-fluorophenyl)-3-{[5-(3-methyl-1H...)
Affinity DataIC50:  10nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16559((2S)-1-(3-methyl-4-fluorophenyl)-3-{[5-(3-methyl-1...)
Affinity DataIC50:  11nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16544((2S)-1-(4-chlorophenyl)-3-{[5-(3-methyl-1H-indazol...)
Affinity DataIC50:  11nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16540((2S)-1-(2,3,4-trifluorophenyl)-3-{[5-(3-methyl-1H-...)
Affinity DataIC50:  12nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16571((2S)-1-[2-fluoro-4-(trifluoromethyl)phenyl]-3-{[5-...)
Affinity DataIC50:  12.1nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Abbott Laboratories

LigandPNGBDBM16587((2S)-1-{[5-(3-methyl-1H-pyrazolo[3,4-c]pyridin-5-y...)
Affinity DataIC50:  13nMAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16578((2S)-1-{[5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl]...)
Affinity DataIC50:  13nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16568((2S)-1-[5-fluoro-3-(trifluoromethyl)phenyl]-3-{[5-...)
Affinity DataIC50:  13.3nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15138(5-indazolyl pyridine 11g | 5-{5-[(2S)-2-amino-3-ph...)
Affinity DataIC50:  14nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15022(3-[(2S)-2-amino-3-({5-[(E)-2-(pyridin-4-yl)ethenyl...)
Affinity DataIC50:  14nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16577((2S)-1-(2,2-difluoro-1,3-benzodioxol-4-yl)-3-{[5-(...)
Affinity DataIC50:  14nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Abbott Laboratories

LigandPNGBDBM16547((2S)-1-(4-bromophenyl)-3-{[5-(3-methyl-1H-indazol-...)
Affinity DataIC50:  15nMAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Abbott Laboratories

LigandPNGBDBM16586((2S)-1-{[5-(3-chloro-1H-pyrazolo[3,4-c]pyridin-5-y...)
Affinity DataIC50:  15nMAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16572((2S)-1-{[5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl]...)
Affinity DataIC50:  15.3nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Abbott Laboratories

LigandPNGBDBM15138(5-indazolyl pyridine 11g | 5-{5-[(2S)-2-amino-3-ph...)
Affinity DataIC50:  16nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
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