Compile Data Set for Download or QSAR
Report error Found 73 Enz. Inhib. hit(s) with all data for entry = 2061
LigandChemical structure of BindingDB Monomer ID 15131BDBM15131(5-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...)
Affinity DataIC50: 0.160nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16531BDBM16531((3Z)-5-(5-{[(2S)-2-amino-3-(1H-indol-3-yl)propyl]o...)
Affinity DataIC50: 0.170nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16532BDBM16532(pyrazolopyridine analog, 9g | (2S)-1-(1H-indol-3-y...)
Affinity DataIC50: 0.340nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16587BDBM16587(3-[(2S)-2-amino-3-[3-(trifluoromethyl)phenyl]propo...)
Affinity DataIC50: 0.600nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16548BDBM16548(5-{5-[(2S)-2-amino-3-(3-iodophenyl)propoxy]pyridin...)
Affinity DataIC50: 0.900nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16564BDBM16564((2S)-1-{[5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl]...)
Affinity DataIC50: 1.20nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16569BDBM16569(5-{5-[(2S)-2-amino-3-[2-fluoro-5-(trifluoromethyl)...)
Affinity DataIC50: 1.20nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16555BDBM16555(5-{5-[(2S)-2-amino-3-(4-bromo-3-fluorophenyl)propo...)
Affinity DataIC50: 1.30nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16535BDBM16535((3E)-5-{5-[(2S)-2-amino-3-phenylpropoxy]pyridin-3-...)
Affinity DataIC50: 1.40nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16552BDBM16552((2S)-1-(3,4-dichlorophenyl)-3-{[5-(3-methyl-1H-ind...)
Affinity DataIC50: 1.80nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16567BDBM16567(5-{5-[(2S)-2-amino-3-[4-fluoro-3-(trifluoromethyl)...)
Affinity DataIC50: 1.80nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 15067BDBM15067(13a (S-) | 6-{5-[(2S)-2-amino-3-(1H-indol-3-yl)pro...)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16546BDBM16546((2S)-1-(3-bromophenyl)-3-{[5-(3-methyl-1H-indazol-...)
Affinity DataIC50: 2.10nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16561BDBM16561(5-{5-[(2S)-2-amino-3-(3-fluoro-4-methylphenyl)prop...)
Affinity DataIC50: 2.40nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16558BDBM16558(5-{5-[(2S)-2-amino-3-(4-bromo-3-methylphenyl)propo...)
Affinity DataIC50: 2.5nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16586BDBM16586((2S)-1-{[5-(3-chloro-1H-pyrazolo[3,4-c]pyridin-5-y...)
Affinity DataIC50: 2.90nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16549BDBM16549((2S)-1-(3-chloro-4-fluorophenyl)-3-{[5-(3-methyl-1...)
Affinity DataIC50: 3.10nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16570BDBM16570(5-{5-[(2S)-2-amino-3-[3-fluoro-4-(trifluoromethyl)...)
Affinity DataIC50: 3.10nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16573BDBM16573((2S)-1-{[5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl]...)
Affinity DataIC50: 3.30nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16550BDBM16550(5-{5-[(2S)-2-amino-3-(4-chloro-3-fluorophenyl)prop...)
Affinity DataIC50: 3.60nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16557BDBM16557(5-{5-[(2S)-2-amino-3-(5-fluoro-2-methylphenyl)prop...)
Affinity DataIC50: 3.90nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16564BDBM16564((2S)-1-{[5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl]...)
Affinity DataIC50: 5nMAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16547BDBM16547(5-{5-[(2S)-2-amino-3-(4-bromophenyl)propoxy]pyridi...)
Affinity DataIC50: 5nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16588BDBM16588((2S)-1-(2,3-difluorophenyl)-3-{[5-(3-methyl-1H-pyr...)
Affinity DataIC50: 5nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16551BDBM16551(5-{5-[(2S)-2-amino-3-(2,3-dichlorophenyl)propoxy]p...)
Affinity DataIC50: 5.60nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16543BDBM16543((2S)-1-(3-chlorophenyl)-3-{[5-(3-methyl-1H-indazol...)
Affinity DataIC50: 5.90nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16560BDBM16560(5-{5-[(2S)-2-amino-3-(4-fluoro-2-methylphenyl)prop...)
Affinity DataIC50: 6nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 15131BDBM15131(5-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...)
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16581BDBM16581(5-{5-[(2S)-2-amino-3-[3-(piperidin-4-ylmethoxy)phe...)
Affinity DataIC50: 6.80nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16588BDBM16588((2S)-1-(2,3-difluorophenyl)-3-{[5-(3-methyl-1H-pyr...)
Affinity DataIC50: 7nMAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16585BDBM16585((2S)-1-{[5-(1H-pyrazolo[3,4-c]pyridin-5-yl)pyridin...)
Affinity DataIC50: 7.20nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16563BDBM16563((2S)-1-(5-fluoro-2-methoxyphenyl)-3-{[5-(3-methyl-...)
Affinity DataIC50: 7.70nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16536BDBM16536(5-{5-[(2S)-2-amino-3-(3-fluorophenyl)propoxy]pyrid...)
Affinity DataIC50: 8.40nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16537BDBM16537(5-{5-[(2S)-2-amino-3-(2,3-difluorophenyl)propoxy]p...)
Affinity DataIC50: 8.5nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16537BDBM16537(5-{5-[(2S)-2-amino-3-(2,3-difluorophenyl)propoxy]p...)
Affinity DataIC50: 9nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16554BDBM16554(5-{5-[(2S)-2-amino-3-(4-bromo-2-fluorophenyl)propo...)
Affinity DataIC50: 10nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16559BDBM16559((2S)-1-(3-methyl-4-fluorophenyl)-3-{[5-(3-methyl-1...)
Affinity DataIC50: 11nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16544BDBM16544((2S)-1-(4-chlorophenyl)-3-{[5-(3-methyl-1H-indazol...)
Affinity DataIC50: 11nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16540BDBM16540(5-{5-[(2S)-2-amino-3-(2,3,4-trifluorophenyl)propox...)
Affinity DataIC50: 12nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16571BDBM16571(5-{5-[(2S)-2-amino-3-[2-fluoro-4-(trifluoromethyl)...)
Affinity DataIC50: 12.1nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16587BDBM16587(3-[(2S)-2-amino-3-[3-(trifluoromethyl)phenyl]propo...)
Affinity DataIC50: 13nMAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16578BDBM16578(5-{5-[(2S)-2-amino-3-(2,2,3,3-tetrafluoro-2,3-dihy...)
Affinity DataIC50: 13nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16568BDBM16568((2S)-1-[5-fluoro-3-(trifluoromethyl)phenyl]-3-{[5-...)
Affinity DataIC50: 13.3nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16577BDBM16577(5-{5-[(2S)-2-amino-3-(2,2-difluoro-2H-1,3-benzodio...)
Affinity DataIC50: 14nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 15022BDBM15022(3-[(2S)-2-amino-3-({5-[(E)-2-(pyridin-4-yl)ethenyl...)
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 15138BDBM15138(Biochemistry 469551 Compound 11 | 5-indazolyl pyri...)
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16586BDBM16586((2S)-1-{[5-(3-chloro-1H-pyrazolo[3,4-c]pyridin-5-y...)
Affinity DataIC50: 15nMAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16547BDBM16547(5-{5-[(2S)-2-amino-3-(4-bromophenyl)propoxy]pyridi...)
Affinity DataIC50: 15nMAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16572BDBM16572(5-{5-[(2S)-2-amino-3-[2-(trifluoromethoxy)phenyl]p...)
Affinity DataIC50: 15.3nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 15138BDBM15138(Biochemistry 469551 Compound 11 | 5-indazolyl pyri...)
Affinity DataIC50: 16nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
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