Compile Data Set for Download or QSAR
maximum 50k data
Found 66 Enz. Inhib. hit(s) with all data for entry = 50041917
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102331(1-(2,5-Dimethyl-thiophen-3-yl)-3-[4-(2-methoxy-phe...)
Affinity DataKi:  5.01nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102377(3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-(thiophen-...)
Affinity DataKi:  6.46nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102352(1-(2,5-Dimethyl-thiophen-3-yl)-3-[4-(2-hydroxy-phe...)
Affinity DataKi:  7.59nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102371(3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-(thiophen-...)
Affinity DataKi:  10nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102412(1-(2,5-Dimethyl-thiophen-3-yl)-3-[4-(2-methoxy-phe...)
Affinity DataKi:  12.0nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102337(3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-(thiophen-...)
Affinity DataKi:  15.8nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102350(3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-(5-methylt...)
Affinity DataKi:  17.4nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102374(3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-phenylprop...)
Affinity DataKi:  17.4nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102330(2-(4-(3-(benzo[b]thiophen-3-yl)-3-hydroxypropyl)pi...)
Affinity DataKi:  18.2nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102355(3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-(thiophen-...)
Affinity DataKi:  19.1nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102359(1-(benzo[b]thiophen-3-yl)-3-(4-(2-methoxyphenyl)pi...)
Affinity DataKi:  19.9nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102384(3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-1-(5-methy...)
Affinity DataKi:  33.9nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102373(3-(4-(naphthalen-1-yl)piperazin-1-yl)-1-(thiophen-...)
Affinity DataKi:  34.7nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102338(1-Benzo[b]thiophen-3-yl-3-[4-(2-methoxy-phenyl)-pi...)
Affinity DataKi:  43.6nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102395(3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-phenylprop...)
Affinity DataKi:  47.9nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102354(3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-phenylprop...)
Affinity DataKi:  50.1nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102383(1-Phenyl-3-(4-pyridin-2-yl-piperazin-1-yl)-propan-...)
Affinity DataKi:  50.1nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102376(3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-(thiophen-...)
Affinity DataKi:  50.1nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102342(2-(4-(3-(2,5-dimethylthiophen-3-yl)-3-hydroxypropy...)
Affinity DataKi:  91.2nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102328(1-(benzo[b]thiophen-3-yl)-3-(4-(naphthalen-1-yl)pi...)
Affinity DataKi:  100nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102343(1-(2,5-Dimethyl-thiophen-3-yl)-3-(4-naphthalen-1-y...)
Affinity DataKi:  100nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102410(1-(benzo[b]thiophen-3-yl)-3-(4-(2-hydroxyphenyl)pi...)
Affinity DataKi:  110nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102351(3-(4-(2-chlorophenyl)piperazin-1-yl)-1-phenylpropa...)
Affinity DataKi:  115nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102396(1-Phenyl-3-(4-pyrimidin-2-yl-piperazin-1-yl)-propa...)
Affinity DataKi:  120nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102394(1-Phenyl-3-(4-pyridin-2-yl-piperazin-1-yl)-propan-...)
Affinity DataKi:  155nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102329(3-(4-(2-chlorophenyl)piperazin-1-yl)-1-phenylpropa...)
Affinity DataKi:  182nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102361(3-(4-(2-chlorophenyl)piperazin-1-yl)-1-(thiophen-3...)
Affinity DataKi:  200nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102409(3-(4-(2-chlorophenyl)piperazin-1-yl)-1-(thiophen-3...)
Affinity DataKi:  200nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102393(3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-(naphthale...)
Affinity DataKi:  251nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102403(1-(2-Methoxy-phenyl)-4-[3-thiophen-3-yl-3-(4-trifl...)
Affinity DataKi:  257nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102379(1-(4-Methoxy-phenyl)-3-[4-(2-methoxy-phenyl)-piper...)
Affinity DataKi:  324nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102363(3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-(5-nitroth...)
Affinity DataKi:  339nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102357(1-Benzo[b]thiophen-3-yl-3-[4-(4-chloro-2-methoxy-p...)
Affinity DataKi:  363nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102385(3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-(naphthale...)
Affinity DataKi:  417nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102332(1-(2-Methoxy-phenyl)-4-[3-phenyl-3-(4-trifluoromet...)
Affinity DataKi:  447nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102362(1-Benzo[b]thiophen-3-yl-3-[4-(4-fluoro-2-methoxy-p...)
Affinity DataKi:  501nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102400(1-(benzo[b]thiophen-3-yl)-3-(4-(4-fluoro-2-methoxy...)
Affinity DataKi:  501nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102336(1-(benzo[b]thiophen-3-yl)-3-(4-(4-chloro-2-methoxy...)
Affinity DataKi:  501nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102335(1-(3-(benzo[d][1,3]dioxol-5-yloxy)-3-phenylpropyl)...)
Affinity DataKi:  550nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102369(3-(4-(4-chlorophenyl)piperazin-1-yl)-1-(thiophen-3...)
Affinity DataKi:  708nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102392(3-(4-(4-chlorophenyl)piperazin-1-yl)-1-phenylpropa...)
Affinity DataKi:  794nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102381(3-(4-(4-fluorophenyl)piperazin-1-yl)-1-phenylpropa...)
Affinity DataKi:  794nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102401(3-(4-(4-chlorophenyl)piperazin-1-yl)-1-phenylpropa...)
Affinity DataKi:  794nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50418577(CHEMBL1785010)
Affinity DataKi:  851nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102408(1-(2-Methoxy-phenyl)-4-[3-(4-methoxy-phenyl)-3-(4-...)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50415827(CHEMBL1095245)
Affinity DataKi:  1.45E+3nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102404(2-(4-(3-phenyl-3-(4-(trifluoromethyl)phenoxy)propy...)
Affinity DataKi:  1.58E+3nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102368(1-(3-phenyl-3-(4-(trifluoromethyl)phenoxy)propyl)-...)
Affinity DataKi:  1.58E+3nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102388(1-(4-Methoxy-phenyl)-3-[4-(2-methoxy-phenyl)-piper...)
Affinity DataKi:  1.74E+3nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50102407(3-(4-(4-chlorophenyl)piperazin-1-yl)-1-(thiophen-3...)
Affinity DataKi:  2.75E+3nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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