Compile Data Set for Download or QSAR
maximum 50k data
Found 49 Enz. Inhib. hit(s) with all data for entry = 2424
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20334(1-Isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-ur...)
Affinity DataEC50:  2.10nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20382(1-({4-[(1R,5S)-8-azabicyclo[3.2.1]octan-8-yl]-2-(3...)
Affinity DataEC50:  10.3nMAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20336(1-isoquinolin-5-yl-3-{[4-(pyrrolidin-1-yl)phenyl]m...)
Affinity DataEC50:  5.30nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20337(1-isoquinolin-5-yl-3-{[4-(piperidin-1-yl)phenyl]me...)
Affinity DataEC50:  7.30nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20338(3-{[4-(azepan-1-yl)phenyl]methyl}-1-isoquinolin-5-...)
Affinity DataEC50:  3.30nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20339(3-{[4-(azocan-1-yl)phenyl]methyl}-1-isoquinolin-5-...)
Affinity DataEC50:  4.70nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20340(1-isoquinolin-5-yl-3-{[4-(4-methylpiperidin-1-yl)p...)
Affinity DataEC50:  9.30nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20341(1-isoquinolin-5-yl-3-{[4-(morpholin-4-yl)phenyl]me...)
Affinity DataEC50:  91nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20342(3-{[4-(2,6-dimethylmorpholin-4-yl)phenyl]methyl}-1...)
Affinity DataEC50:  258nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20343(1-isoquinolin-5-yl-3-{[4-(thiomorpholin-4-yl)pheny...)
Affinity DataEC50:  23.8nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20344(3-({4-[(1R,5S)-8-azabicyclo[3.2.1]octan-8-yl]pheny...)
Affinity DataEC50:  3.30nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20345(3-{[4-(azepan-1-yl)phenyl]methyl}-1-(3-methylisoqu...)
Affinity DataEC50:  3.80nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20346(1-(3-aminoisoquinolin-5-yl)-3-{[4-(azepan-1-yl)phe...)
Affinity DataEC50:  9.80nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20347(1-(3-chloroisoquinolin-5-yl)-3-{[4-(morpholin-4-yl...)
Affinity DataEC50:  156nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20348(3-{[4-(azepan-1-yl)-2-chlorophenyl]methyl}-1-isoqu...)
Affinity DataEC50:  5.20nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20349(3-{[4-(azepan-1-yl)-2-(trifluoromethyl)phenyl]meth...)
Affinity DataEC50:  5.70nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20350(3-{[4-(azepan-1-yl)-3-(trifluoromethyl)phenyl]meth...)
Affinity DataEC50:  4.60nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20351(3-{[4-(azepan-1-yl)-3-fluorophenyl]methyl}-1-isoqu...)
Affinity DataEC50:  2.80nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20352(3-{[3,5-difluoro-4-(morpholin-4-yl)phenyl]methyl}-...)
Affinity DataEC50:  9.30nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20353(3-{[3-fluoro-4-(pyrrolidin-1-yl)phenyl]methyl}-1-(...)
Affinity DataEC50:  15.5nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20354(3-{[4-(2,3-dihydro-1H-isoindol-2-yl)-3-fluoropheny...)
Affinity DataEC50:  7.36E+3nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20355(1-(3-aminoisoquinolin-5-yl)-3-({4-[(1R,5S)-8-azabi...)
Affinity DataEC50:  14nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20356(1-{[4-(azepan-1-yl)-2-chlorophenyl]methyl}-3-1H-in...)
Affinity DataEC50:  190nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20357(1-{[4-(azepan-1-yl)-2-(trifluoromethyl)phenyl]meth...)
Affinity DataEC50:  133nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20358(1-{[4-(azepan-1-yl)-3-(trifluoromethyl)phenyl]meth...)
Affinity DataEC50:  29.5nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20359(1-{[4-(azepan-1-yl)-3-fluorophenyl]methyl}-3-1H-in...)
Affinity DataEC50:  14.2nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20360(1-{[4-(azepan-1-yl)-3,5-difluorophenyl]methyl}-3-1...)
Affinity DataEC50:  39.3nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20361(1-({4-[(1R,5S)-8-azabicyclo[3.2.1]octan-8-yl]pheny...)
Affinity DataEC50:  18nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20362(1-({4-[(1R,5S)-8-azabicyclo[3.2.1]octan-8-yl]-2-ch...)
Affinity DataEC50:  58.8nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20363(1-({4-[(1R,5S)-8-azabicyclo[3.2.1]octan-8-yl]-2-(t...)
Affinity DataEC50:  54.5nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20364(1-({4-[(1R,5S)-8-azabicyclo[3.2.1]octan-8-yl]-3-(t...)
Affinity DataEC50:  26.9nMAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20365(1-({4-[(1R,5S)-8-azabicyclo[3.2.1]octan-8-yl]-3-ch...)
Affinity DataEC50:  20.4nMAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20366(1-({4-[(1R,5S)-8-azabicyclo[3.2.1]octan-8-yl]-3-br...)
Affinity DataEC50:  43.2nMAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20367(1-({4-[(1R,5S)-8-azabicyclo[3.2.1]octan-8-yl]-3-fl...)
Affinity DataEC50:  14.8nMAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20368(1-({4-[(1R,5S)-8-azabicyclo[3.2.1]octan-8-yl]-3,5-...)
Affinity DataEC50:  12.6nMAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20369(1-({4-[(1R,5S)-8-azabicyclo[3.2.1]octan-8-yl]-2,3-...)
Affinity DataEC50:  25.5nMAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20370(1-({4-[(1R,5S)-8-azabicyclo[3.2.1]octan-8-yl]-2,5-...)
Affinity DataEC50:  21.3nMAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20371(1-({4-[(1S,5R)-8-azaspiro[bicyclo[3.2.1]octane-3,2...)
Affinity DataEC50:  82nMAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20372(1-({2,5-difluoro-4-[(1R,5S)-3-oxo-8-azabicyclo[3.2...)
Affinity DataEC50:  157nMAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20373(1-(1-Methyl-1H-indazol-4-yl)-3-((1-methyl-1H-indol...)
Affinity DataEC50:  1.85E+3nMAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20374(1-[(1-ethyl-2,3-dihydro-1H-indol-5-yl)methyl]-3-1H...)
Affinity DataEC50:  285nMAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20375(1-[(1-ethyl-2,3-dihydro-1H-indol-5-yl)methyl]-3-(1...)
Affinity DataEC50:  305nMAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20376(3-1H-indazol-4-yl-1-[(9-methyl-9H-carbazol-3-yl)me...)
Affinity DataEC50:  902nMAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20377(1-({4-[(1R,5S)-8-azabicyclo[3.2.1]octan-8-yl]-3-me...)
Affinity DataEC50:  19.8nMAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20378(1-({4-[(1R,5S)-8-azabicyclo[3.2.1]octan-8-yl]-2-me...)
Affinity DataEC50:  29nMAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20379(1-(2-Benzyl-4-(8-azabicyclo[3.2.1]octan-8-yl)benzy...)
Affinity DataEC50:  22.4nMAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20380(1-({4-[(1R,5S)-8-azabicyclo[3.2.1]octan-8-yl]-2-be...)
Affinity DataEC50:  19nMAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20381(1-({4-[(1R,5S)-8-azabicyclo[3.2.1]octan-8-yl]-2-(p...)
Affinity DataEC50:  35.3nMAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20335(3-{[4-(dimethylamino)phenyl]methyl}-1-isoquinolin-...)
Affinity DataEC50:  157nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed