Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50020844
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218239BDBM50218239((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...)
Affinity DataIC50: 0.0600nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218213BDBM50218213(1-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50: 0.0700nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218225BDBM50218225(1-(4-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)ph...)
Affinity DataIC50: 0.0700nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218240BDBM50218240(3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50: 0.0700nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218220BDBM50218220(3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50: 0.0900nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218220BDBM50218220(3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50: 0.0900nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218235BDBM50218235(1-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50: 0.0900nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218224BDBM50218224(1-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50: 0.0900nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218212BDBM50218212((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...)
Affinity DataIC50: 0.100nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218217BDBM50218217((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...)
Affinity DataIC50: 0.110nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218227BDBM50218227(3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50: 0.110nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218226BDBM50218226(3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50: 0.110nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218230BDBM50218230(((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)...)
Affinity DataIC50: 0.120nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218231BDBM50218231(4-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50: 0.120nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218233BDBM50218233((S)-5-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)p...)
Affinity DataIC50: 0.120nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218234BDBM50218234(3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50: 0.130nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218222BDBM50218222(3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50: 0.130nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218218BDBM50218218((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...)
Affinity DataIC50: 0.140nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218221BDBM50218221(1-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50: 0.150nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218215BDBM50218215(((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)...)
Affinity DataIC50: 0.160nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218232BDBM50218232(4-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50: 0.160nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218216BDBM50218216(1-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50: 0.180nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218228BDBM50218228(3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50: 0.180nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218214BDBM50218214((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...)
Affinity DataIC50: 0.240nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218237BDBM50218237(3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50: 0.300nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218237BDBM50218237(3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50: 0.300nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218229BDBM50218229(1-(4-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)ph...)
Affinity DataIC50: 0.300nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218219BDBM50218219((S)-4-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)p...)
Affinity DataIC50: 0.340nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218236BDBM50218236((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)e...)
Affinity DataIC50: 0.380nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218223BDBM50218223(((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)...)
Affinity DataIC50: 0.470nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218238BDBM50218238((3S,4R)-N-((2H-1,2,3-triazol-4-yl)methyl)-3-((R)-1...)
Affinity DataIC50: 0.580nMAssay Description:Displacement of [3H]SP from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218227BDBM50218227(3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50: 1.73E+3nMAssay Description:Binding affinity to NK2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50218227BDBM50218227(3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50: 3.00E+3nMAssay Description:Binding affinity to NK3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed