Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50021133
TargetDelta-type opioid receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50221416(CHEMBL401093 | 22-methyl-14-oxa-11,22-diazaheptacy...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]p-Cl-DPDPE from delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50221413((1S,2S,13R,21R)-7-fluoro-22-methyl-14-oxa-11,22-di...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]p-Cl-DPDPE from delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50221417((1S,2S,13R,21R)-7-iodo-22-methyl-14-oxa-11,22-diaz...)
Affinity DataKi:  3.80nMAssay Description:Displacement of [3H]p-Cl-DPDPE from delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50221414((1S,2S,13R,21R)-7-chloro-22-methyl-14-oxa-11,22-di...)
Affinity DataKi:  5.10nMAssay Description:Displacement of [3H]p-Cl-DPDPE from delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50221415((1S,2S,13R,21R)-7-bromo-22-methyl-14-oxa-11,22-dia...)
Affinity DataKi:  8.60nMAssay Description:Displacement of [3H]p-Cl-DPDPE from delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50221413((1S,2S,13R,21R)-7-fluoro-22-methyl-14-oxa-11,22-di...)
Affinity DataEC50:  16nMAssay Description:Activity at delta opioid receptor assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50221413((1S,2S,13R,21R)-7-fluoro-22-methyl-14-oxa-11,22-di...)
Affinity DataKi:  21nMAssay Description:Activity at mu opioid receptor assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50221414((1S,2S,13R,21R)-7-chloro-22-methyl-14-oxa-11,22-di...)
Affinity DataKi:  47nMAssay Description:Activity at mu opioid receptor assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50221417((1S,2S,13R,21R)-7-iodo-22-methyl-14-oxa-11,22-diaz...)
Affinity DataKi:  66nMAssay Description:Activity at mu opioid receptor assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50221415((1S,2S,13R,21R)-7-bromo-22-methyl-14-oxa-11,22-dia...)
Affinity DataKi:  71nMAssay Description:Activity at mu opioid receptor assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50221416(CHEMBL401093 | 22-methyl-14-oxa-11,22-diazaheptacy...)
Affinity DataKi:  105nMAssay Description:Activity at mu opioid receptor assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50221417((1S,2S,13R,21R)-7-iodo-22-methyl-14-oxa-11,22-diaz...)
Affinity DataKi:  160nMAssay Description:Displacement of [3H]U-69593 from cloned kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50221415((1S,2S,13R,21R)-7-bromo-22-methyl-14-oxa-11,22-dia...)
Affinity DataKi:  250nMAssay Description:Displacement of [3H]U-69593 from cloned kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50221413((1S,2S,13R,21R)-7-fluoro-22-methyl-14-oxa-11,22-di...)
Affinity DataKi:  310nMAssay Description:Displacement of [3H]U-69593 from cloned kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50221414((1S,2S,13R,21R)-7-chloro-22-methyl-14-oxa-11,22-di...)
Affinity DataKi:  360nMAssay Description:Displacement of [3H]U-69593 from cloned kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50221416(CHEMBL401093 | 22-methyl-14-oxa-11,22-diazaheptacy...)
Affinity DataKi:  515nMAssay Description:Displacement of [3H]U-69593 from cloned kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50221413((1S,2S,13R,21R)-7-fluoro-22-methyl-14-oxa-11,22-di...)
Affinity DataEC50:  1.08E+3nMAssay Description:Activity at mu opioid receptor assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed