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Found
156
Enz. Inhib. hit(s) with all data for entry = 4641
Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM81444
(NSC_185453 | CAS_185453 | WB 4101 | WB-4101)
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Affinity Data
Ki: 0.600nM
More data for this Ligand-Target Pair
Target Info
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PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
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PubMed
Copy reaction URL
Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM30712
(SMR000059324 | Oxymetazoline | cid_66259 | 6-tert-...)
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Affinity Data
Ki: 1.90nM
More data for this Ligand-Target Pair
Target Info
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DrugBank
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PC cid
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In Depth
Date in BDB:
9/24/2011
Entry Details
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PubMed
PDB
3D Structure (crystal)
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM81453
(NSC_159729 | CAS_159729 | Dihydro-alpha-ergocrypti...)
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Affinity Data
Ki: 2.40nM
More data for this Ligand-Target Pair
Target Info
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KEGG
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KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM32638
(Dihydroergocristine | NSC409663)
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Affinity Data
Ki: 2.40nM
More data for this Ligand-Target Pair
Target Info
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PC cid
PC sid
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In Depth
Date in BDB:
9/24/2011
Entry Details
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PubMed
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50280055
(7-Methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-...)
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Affinity Data
Ki: 2.40nM
More data for this Ligand-Target Pair
Target Info
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PC cid
PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
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PubMed
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50280055
(7-Methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-...)
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Affinity Data
Ki: 3.5nM
More data for this Ligand-Target Pair
Target Info
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PC cid
PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
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PubMed
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM31046
(SMR000059054 | cid_91430 | 3-[4,5-dihydro-1H-imida...)
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Affinity Data
Ki: 3.60nM
More data for this Ligand-Target Pair
Target Info
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DrugBank
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM81460
(NSC_168871 | CAS_168871 | Dihydroergocornine)
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Affinity Data
Ki: 3.70nM
More data for this Ligand-Target Pair
Target Info
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PC cid
PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50017679
(CHEMBL753 | Dibenzyline | Benzyl-(2-chloro-ethyl)-...)
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Affinity Data
Ki: 4nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
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KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50027056
(CHEMBL32573 | Tramazoline | Imidazolidin-2-ylidene...)
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Affinity Data
Ki: 4.20nM
More data for this Ligand-Target Pair
Target Info
PDB
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CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
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PubMed
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM30703
(SMR000058526 | 2-[(4-tert-butyl-2,6-dimethyl-pheny...)
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Affinity Data
Ki: 4.80nM
More data for this Ligand-Target Pair
Target Info
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KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
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PubMed
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50002338
(10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...)
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Affinity Data
Ki: 5.10nM
More data for this Ligand-Target Pair
Target Info
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PC cid
PC sid
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In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50016897
(2-(2,6-dichloroanilino)-2-imidazoline | 2-(2,6-dic...)
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Affinity Data
Ki: 5.70nM
More data for this Ligand-Target Pair
Target Info
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PC cid
PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50001922
(Naphazoline | Albalon | Opcon | CHEMBL1706 | Nafaz...)
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Affinity Data
Ki: 5.70nM
More data for this Ligand-Target Pair
Target Info
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KEGG
PC cid
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In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50033113
(N-{1-[2-(1H-Indol-3-yl)-ethyl]-piperidin-4-yl}-ben...)
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Affinity Data
Ki: 5.90nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50029050
(4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2...)
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Affinity Data
Ki: 5.90nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
DrugBank
KEGG
PC cid
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In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
PDB
3D Structure (crystal)
Copy reaction URL
Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50001888
([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
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Affinity Data
Ki: 6.20nM
More data for this Ligand-Target Pair
Target Info
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KEGG
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CHEMBL
DrugBank
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
Copy reaction URL
Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM30702
(SMR000058447 | MLS000069350 | ERGOCRISTINE | cid_3...)
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Affinity Data
Ki: 6.30nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
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KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
Copy reaction URL
Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM81453
(NSC_159729 | CAS_159729 | Dihydro-alpha-ergocrypti...)
Copy SMILES
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Affinity Data
Ki: 7nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
Copy reaction URL
Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM81454
(CAS_3087850 | NSC_3087850 | St-600)
Copy SMILES
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Affinity Data
Ki: 7.60nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
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GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
Copy reaction URL
Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50027502
(alpha-Methyl-(+/-)norepinephrine,(+/-) | Aldoclor-...)
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Affinity Data
Ki: 7.70nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
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CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
Copy reaction URL
Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50855
(ALPHA-ERGOCRYPTINE | MLS000069839 | SMR000058703 |...)
Copy SMILES
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Affinity Data
Ki: 8nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
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PC cid
PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
Copy reaction URL
Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM81460
(NSC_168871 | CAS_168871 | Dihydroergocornine)
Copy SMILES
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Affinity Data
Ki: 9nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
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PC cid
PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM81993
(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)
Copy SMILES
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Affinity Data
Ki: 9nM
More data for this Ligand-Target Pair
Target Info
PDB
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DrugBank
KEGG
PC cid
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PDB
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
Copy reaction URL
Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50855
(ALPHA-ERGOCRYPTINE | MLS000069839 | SMR000058703 |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 9nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
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PC cid
PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
Copy reaction URL
Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM32638
(Dihydroergocristine | NSC409663)
Copy SMILES
Copy InChI
Affinity Data
Ki: 10nM
More data for this Ligand-Target Pair
Target Info
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PC cid
PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
Copy reaction URL
Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM30709
(ERGOCORNINE | SMR000058938 | MLS000069342 | cid_73...)
Copy SMILES
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Affinity Data
Ki: 10nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
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KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM96559
(cid_10648 | Tetrahydrozoline hydrochloride | 2-(1,...)
Copy SMILES
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Affinity Data
Ki: 11nM
More data for this Ligand-Target Pair
Target Info
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DrugBank
KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
Copy reaction URL
Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Copy SMILES
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Affinity Data
Ki: 11nM
More data for this Ligand-Target Pair
Target Info
PDB
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CHEMBL
DrugBank
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
Copy reaction URL
Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM30709
(ERGOCORNINE | SMR000058938 | MLS000069342 | cid_73...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 11nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
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KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
Copy reaction URL
Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50027065
(12'-hydroxy-2'-methyl-5'alpha-(phenylmethyl)ergota...)
Copy SMILES
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Affinity Data
Ki: 12nM
More data for this Ligand-Target Pair
Target Info
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DrugBank
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
Copy reaction URL
Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50027065
(12'-hydroxy-2'-methyl-5'alpha-(phenylmethyl)ergota...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 12nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
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DrugBank
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM81993
(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)
Copy SMILES
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Affinity Data
Ki: 16nM
More data for this Ligand-Target Pair
Target Info
PDB
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DrugBank
KEGG
PC cid
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Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50027502
(alpha-Methyl-(+/-)norepinephrine,(+/-) | Aldoclor-...)
Copy SMILES
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Affinity Data
Ki: 16nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
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PC cid
PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM162127
((+)-noradrenaline | (+)-norepinephrine | (S)-norad...)
Copy SMILES
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Affinity Data
Ki: 17nM
More data for this Ligand-Target Pair
Target Info
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PC cid
PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM30702
(SMR000058447 | MLS000069350 | ERGOCRISTINE | cid_3...)
Copy SMILES
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Affinity Data
Ki: 18nM
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
Copy reaction URL
Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM81457
(CAS_7762-32-5 | NSC_94342 | Dibozane)
Copy SMILES
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Affinity Data
Ki: 19nM
More data for this Ligand-Target Pair
Target Info
PDB
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Ligand Info
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PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
Copy reaction URL
Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50020712
(CHEMBL629 | Amitriptylin | 10,11-dihydro-N,N-dimet...)
Copy SMILES
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Affinity Data
Ki: 21nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
DrugBank
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PC cid
PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
Copy reaction URL
Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM31046
(SMR000059054 | cid_91430 | 3-[4,5-dihydro-1H-imida...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 22nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
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DrugBank
PC cid
PC sid
Similars
In Depth
Date in BDB:
9/24/2011
Entry Details
Copy BDB DOI
PubMed
Copy reaction URL
Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM30712
(SMR000059324 | Oxymetazoline | cid_66259 | 6-tert-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 24nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
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Ligand Info
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Date in BDB:
9/24/2011
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3D Structure (crystal)
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM30703
(SMR000058526 | 2-[(4-tert-butyl-2,6-dimethyl-pheny...)
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Affinity Data
Ki: 39nM
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Date in BDB:
9/24/2011
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM79181
(cid_2913535 | TRIFLUOPERAZINE | SMR000059133 | MLS...)
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Affinity Data
Ki: 44nM
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Date in BDB:
9/24/2011
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM86698
(CHEMBL116590 | CAS_132-17-2 | NSC_2344 | BENZTROPI...)
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Affinity Data
Ki: 47nM
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Date in BDB:
9/24/2011
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50010859
(CHEMBL11 | Imipramin | IMIPRAMINE HYDROCHLORIDE | ...)
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Affinity Data
Ki: 51nM
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Date in BDB:
9/24/2011
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50017696
(N,N,alpha-trimethyl-10H-phenothiazine-10-ethanamin...)
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Ki: 55nM
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Date in BDB:
9/24/2011
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50017679
(CHEMBL753 | Dibenzyline | Benzyl-(2-chloro-ethyl)-...)
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Ki: 60nM
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Date in BDB:
9/24/2011
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50087512
((S)-adrenaline | (+)-adrenaline | CHEMBL42280)
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Ki: 65nM
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Date in BDB:
9/24/2011
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM81445
(NSC_5820 | CAS_55-43-6 | Dibenamine)
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Ki: 83nM
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Date in BDB:
9/24/2011
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM50017720
(Piperoxan | CHEMBL31836 | PIPEROXAN1-(2,3-Dihydro-...)
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Ki: 95nM
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In Depth
Date in BDB:
9/24/2011
Entry Details
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Target
Alpha-1A adrenergic receptor
(Rat)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM81457
(CAS_7762-32-5 | NSC_94342 | Dibozane)
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Affinity Data
Ki: 100nM
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Target Info
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Date in BDB:
9/24/2011
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