Compile Data Set for Download or QSAR
maximum 50k data
Found 42 Enz. Inhib. hit(s) with all data for entry = 50021221
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222230((E)-N-((1S,3R)-3-((4-(4-methoxyphenyl)piperidin-1-...)
Affinity DataIC50:  80nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222258((E)-N-(3-((4-(4-methoxyphenyl)piperidin-1-yl)methy...)
Affinity DataIC50:  130nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222246((E)-3-(3,4-dichlorophenyl)-N-(3-((4-(4-methoxyphen...)
Affinity DataIC50:  140nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222237((E)-3-(3,5-dichlorophenyl)-N-((1S,3R)-3-((4-(4-met...)
Affinity DataIC50:  160nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222242((E)-3-(3,5-difluorophenyl)-N-((1S,3R)-3-((4-(4-met...)
Affinity DataIC50:  160nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222231((E)-3-(3,5-dichlorophenyl)-N-(3-((4-(4-methoxyphen...)
Affinity DataIC50:  180nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222240((E)-3-(3,5-difluorophenyl)-N-(3-((4-(4-methoxyphen...)
Affinity DataIC50:  240nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222227((E)-1-(4-((4-(4-chlorophenyl)piperidin-1-yl)methyl...)
Affinity DataIC50:  300nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222227((E)-1-(4-((4-(4-chlorophenyl)piperidin-1-yl)methyl...)
Affinity DataIC50:  300nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222232((E)-3-(3,4-dichlorophenyl)-1-(4-((4-(4-methoxyphen...)
Affinity DataIC50:  320nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222256((E)-3-(3,4-dichlorophenyl)-1-(4-((4-(4-hydroxyphen...)
Affinity DataIC50:  510nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222244((E)-3-(3,5-difluorophenyl)-N-(3-((4-(3,4-difluorop...)
Affinity DataIC50:  790nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222229((E)-3-(3,4-dichlorophenyl)-1-(4-((4-(4-(dimethylam...)
Affinity DataIC50:  950nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222252((E)-N-(5-(4-(4-chlorophenyl)piperidin-1-yl)pentyl)...)
Affinity DataIC50:  1.20E+3nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222253((E)-1-(4-((4-(4-chlorophenyl)piperidin-1-yl)methyl...)
Affinity DataIC50:  1.40E+3nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222239((E)-3-(3,4-dichlorophenyl)-N-(5-(4-(4-methoxypheny...)
Affinity DataIC50:  1.50E+3nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222236((E)-N-(5-(4-(4-chlorophenyl)piperidin-1-yl)pentyl)...)
Affinity DataIC50:  1.80E+3nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222226((E)-N-(4-(4-(4-chlorophenyl)piperidin-1-yl)butyl)-...)
Affinity DataIC50:  1.90E+3nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222225((E)-1-(4-((4-(4-chlorophenyl)piperidin-1-yl)methyl...)
Affinity DataIC50:  2.00E+3nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222254((E)-3-(4-fluorophenyl)-N-(5-(4-(4-methoxyphenyl)pi...)
Affinity DataIC50:  2.10E+3nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222248((E)-3-(3,4-dichlorophenyl)-1-(4-((4-p-tolylpiperid...)
Affinity DataIC50:  2.20E+3nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222234((E)-3-(4-fluorophenyl)-N-(4-(4-(4-methoxyphenyl)pi...)
Affinity DataIC50:  2.30E+3nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222238((E)-3-(3,4-dichlorophenyl)-N-(4-(4-(4-methoxypheny...)
Affinity DataIC50:  2.60E+3nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222224((E)-1-(4-(2-(4-(4-chlorophenyl)piperidin-1-yl)ethy...)
Affinity DataIC50:  2.90E+3nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222250((E)-N-(4-(4-(4-chlorophenyl)piperidin-1-yl)butyl)-...)
Affinity DataIC50:  2.90E+3nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222245((E)-N-(4-(4-(4-chlorophenyl)piperidin-1-yl)butyl)-...)
Affinity DataIC50:  3.10E+3nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222257((E)-N-(4-(4-(4-methoxyphenyl)piperidin-1-yl)butyl)...)
Affinity DataIC50:  3.40E+3nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222243((E)-3-(3,5-difluorophenyl)-N-(4-(4-(4-methoxypheny...)
Affinity DataIC50:  3.80E+3nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222255((E)-3-(3,4-dichlorophenyl)-1-(4-((4-(3-methoxyphen...)
Affinity DataIC50:  4.00E+3nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222259((E)-N-(4-(4-(4-chlorophenyl)piperidin-1-yl)butyl)-...)
Affinity DataIC50:  4.50E+3nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222235((E)-3-(4-bromophenyl)-1-(4-((4-(4-chlorophenyl)pip...)
Affinity DataIC50:  5.20E+3nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222247((E)-1-(4-((4-(4-chlorophenyl)piperidin-1-yl)methyl...)
Affinity DataIC50:  5.90E+3nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222228((E)-3-(3,5-dichlorophenyl)-N-((1R,3S)-3-((4-(4-met...)
Affinity DataIC50:  6.45E+3nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222251((E)-N-((1R,3S)-3-((4-(4-methoxyphenyl)piperidin-1-...)
Affinity DataIC50:  8.40E+3nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222249((E)-3-(3,4-dichlorophenyl)-1-(4-((4-(2-methoxyphen...)
Affinity DataIC50:  1.11E+4nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222241((E)-3-(3,5-difluorophenyl)-N-((1R,3S)-3-((4-(4-met...)
Affinity DataIC50:  1.20E+4nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222233((E)-3-(3,4-dichlorophenyl)-N-(5-(4-(4-hydroxypheny...)
Affinity DataIC50:  1.26E+4nMAssay Description:Displacement of [125]MCP1 from human CCR2 receptor in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222227((E)-1-(4-((4-(4-chlorophenyl)piperidin-1-yl)methyl...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222227((E)-1-(4-((4-(4-chlorophenyl)piperidin-1-yl)methyl...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222227((E)-1-(4-((4-(4-chlorophenyl)piperidin-1-yl)methyl...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222227((E)-1-(4-((4-(4-chlorophenyl)piperidin-1-yl)methyl...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50222227((E)-1-(4-((4-(4-chlorophenyl)piperidin-1-yl)methyl...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed