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Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50021377
TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223939(6-(4-methoxybenzyl)-7-neopentyl-7H-pyrrolo[2,3-d]p...)
Affinity DataIC50:  1nMAssay Description:Inhibition of cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223914(6-((4-(4-fluorophenyl)piperazin-1-yl)methyl)-7-neo...)
Affinity DataIC50:  1nMAssay Description:Inhibition of cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223921(6-(4-(benzo[d][1,3]dioxol-5-yl)benzyl)-7-neopentyl...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223935(CHEMBL399842 | N-(4-((2-cyano-7-neopentyl-7H-pyrro...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223915(6-benzyl-7-neopentyl-7H-pyrrolo[2,3-d]pyrimidine-2...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223925(6-(4-((4-methylpiperazin-1-yl)methyl)benzyl)-7-cyc...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223919(7-(2,2-dimethylpropyl)-6-[(5-fluoro-2-oxospiro[ind...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223910(6-(4-chlorobenzyl)-7-cyclohexyl-7H-pyrrolo[2,3-d]p...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223911(7-neopentyl-6-((pyridin-4-yloxy)methyl)-7H-pyrrolo...)
Affinity DataIC50:  3nMAssay Description:Inhibition of cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223920(6-(4-morpholinobenzyl)-7-cyclohexyl-7H-pyrrolo[2,3...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223936(6-((5,5-dimethyl-2,4-dioxooxazolidin-3-yl)methyl)-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223940(6-((4,5-dichloro-1H-imidazol-1-yl)methyl)-7-neopen...)
Affinity DataIC50:  4nMAssay Description:Inhibition of cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223941(6-(4-((diethylamino)methyl)benzyl)-7-cyclohexyl-7H...)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223937(6-((1H-1,2,3-triazol-1-yl)methyl)-7-neopentyl-7H-p...)
Affinity DataIC50:  5nMAssay Description:Inhibition of cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223918(6-((1H-imidazol-1-yl)methyl)-7-neopentyl-7H-pyrrol...)
Affinity DataIC50:  6nMAssay Description:Inhibition of cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223923(6-benzyl-7-cyclohexyl-7H-pyrrolo[2,3-d]pyrimidine-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223928(6-biphenyl-4-ylmethyl-7-cyclohexyl-7H-pyrrolo[2,3-...)
Affinity DataIC50:  47nMAssay Description:Inhibition of cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223915(6-benzyl-7-neopentyl-7H-pyrrolo[2,3-d]pyrimidine-2...)
Affinity DataIC50:  100nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223927(CHEMBL251186 | N-(4-((2-cyano-7-neopentyl-7H-pyrro...)
Affinity DataIC50:  160nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223930(CHEMBL251187 | N-{4-[(2-cyano-7-neopentyl-7H-pyrro...)
Affinity DataIC50:  220nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223933(CHEMBL250793 | N-(4-((2-cyano-7-neopentyl-7H-pyrro...)
Affinity DataIC50:  320nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223923(6-benzyl-7-cyclohexyl-7H-pyrrolo[2,3-d]pyrimidine-...)
Affinity DataIC50:  390nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223935(CHEMBL399842 | N-(4-((2-cyano-7-neopentyl-7H-pyrro...)
Affinity DataIC50:  440nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223931(6-(4-(4-methylpiperazin-1-yl)benzyl)-7-cyclohexyl-...)
Affinity DataIC50:  460nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223938(6-(4-chlorobenzyl)-7-neopentyl-7H-pyrrolo[2,3-d]py...)
Affinity DataIC50:  460nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223910(6-(4-chlorobenzyl)-7-cyclohexyl-7H-pyrrolo[2,3-d]p...)
Affinity DataIC50:  490nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223925(6-(4-((4-methylpiperazin-1-yl)methyl)benzyl)-7-cyc...)
Affinity DataIC50:  730nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223939(6-(4-methoxybenzyl)-7-neopentyl-7H-pyrrolo[2,3-d]p...)
Affinity DataIC50:  820nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223919(7-(2,2-dimethylpropyl)-6-[(5-fluoro-2-oxospiro[ind...)
Affinity DataIC50:  930nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223909(7-(2,2-dimethyl-propyl)-6-(4-methyl-benzyl)-7H-pyr...)
Affinity DataIC50:  930nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223920(6-(4-morpholinobenzyl)-7-cyclohexyl-7H-pyrrolo[2,3...)
Affinity DataIC50:  980nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223911(7-neopentyl-6-((pyridin-4-yloxy)methyl)-7H-pyrrolo...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223941(6-(4-((diethylamino)methyl)benzyl)-7-cyclohexyl-7H...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223913(6-((1,3-dioxo-2,8-diazaspiro[4.5]decan-2-yl)methyl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223916(6-(4-(4-methylpiperazin-1-yl)benzyl)-7-neopentyl-7...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223917(6-(4-morpholinobenzyl)-7-neopentyl-7H-pyrrolo[2,3-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223918(6-((1H-imidazol-1-yl)methyl)-7-neopentyl-7H-pyrrol...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223934(7-(2,2-Dimethyl-propyl)-6-(2,4-dioxo-8-propyl-1,3,...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223912(6-(4-((diethylamino)methyl)benzyl)-7-neopentyl-7H-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223928(6-biphenyl-4-ylmethyl-7-cyclohexyl-7H-pyrrolo[2,3-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223929(7-(2,2-Dimethyl-propyl)-6-(3-methyl-2,4-dioxo-1,3,...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223914(6-((4-(4-fluorophenyl)piperazin-1-yl)methyl)-7-neo...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223922(6-(4-((4-methylpiperazin-1-yl)methyl)benzyl)-7-neo...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223924(4-((2-cyano-7-neopentyl-7H-pyrrolo[2,3-d]pyrimidin...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223936(6-((5,5-dimethyl-2,4-dioxooxazolidin-3-yl)methyl)-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223937(6-((1H-1,2,3-triazol-1-yl)methyl)-7-neopentyl-7H-p...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223921(6-(4-(benzo[d][1,3]dioxol-5-yl)benzyl)-7-neopentyl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223926(6-(4-(dimethylamino)benzyl)-7-neopentyl-7H-pyrrolo...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223932(6-(4-(naphthalen-2-yl)benzyl)-7-neopentyl-7H-pyrro...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223940(6-((4,5-dichloro-1H-imidazol-1-yl)methyl)-7-neopen...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed