Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50021444
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224734BDBM50224734(2-(4-(6-chloro-2-(4-(dimethylamino)phenyl)-3H-imid...)
Affinity DataIC50: 42nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase B(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224734BDBM50224734(2-(4-(6-chloro-2-(4-(dimethylamino)phenyl)-3H-imid...)
Affinity DataIC50: 198nMAssay Description:Inhibition of recombinant aurora B kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase C(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224734BDBM50224734(2-(4-(6-chloro-2-(4-(dimethylamino)phenyl)-3H-imid...)
Affinity DataIC50: 227nMAssay Description:Inhibition of recombinant aurora C kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224749BDBM50224749(4-(6,7-dichloro-3H-imidazo[4,5-b]pyridin-2-yl)-N,N...)
Affinity DataIC50: 250nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224745BDBM50224745(4-(6-bromo-3H-imidazo[4,5-b]pyridin-2-yl)-N,N-dime...)
Affinity DataIC50: 490nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224731BDBM50224731(4-(6-chloro-3H-imidazo[4,5-b]pyridin-2-yl)-N,N-dim...)
Affinity DataIC50: 570nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224750BDBM50224750(N,N-dimethyl-4-(6-(trifluoromethyl)-3H-imidazo[4,5...)
Affinity DataIC50: 740nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224742BDBM50224742(2-(4-(2-(4-(dimethylamino)phenyl)-3H-imidazo[4,5-b...)
Affinity DataIC50: 870nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224738BDBM50224738(4-(7-chloro-3H-imidazo[4,5-b]pyridin-2-yl)-N,N-dim...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224740BDBM50224740(4-(3H-imidazo[4,5-b]pyridin-2-yl)-N,N-dimethylbenz...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224751BDBM50224751(2-(4-(piperidin-2-yl)phenyl)-3H-imidazo[4,5-b]pyri...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224736BDBM50224736(2-(4-(pyrrolidin-1-yl)phenyl)-3H-imidazo[4,5-b]pyr...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224754BDBM50224754(2-(4-(6,7-dimethoxyquinazolin-4-yl)piperazin-1-yl)...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224752BDBM50224752(2-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridine | 2-...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224737BDBM50224737(N,N-dimethyl-4-(6-methyl-3H-imidazo[4,5-b]pyridin-...)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224733BDBM50224733(N,N-dimethyl-4-(7-methyl-3H-imidazo[4,5-b]pyridin-...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224753BDBM50224753(1-(3-(2-(4-(dimethylamino)phenyl)-3H-imidazo[4,5-b...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224748BDBM50224748(6,7-dimethoxy-4-(4-(naphthalen-1-ylmethyl)piperazi...)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224734BDBM50224734(2-(4-(6-chloro-2-(4-(dimethylamino)phenyl)-3H-imid...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP1A2 after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224734BDBM50224734(2-(4-(6-chloro-2-(4-(dimethylamino)phenyl)-3H-imid...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP2A6 after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224734BDBM50224734(2-(4-(6-chloro-2-(4-(dimethylamino)phenyl)-3H-imid...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP2C19 after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224734BDBM50224734(2-(4-(6-chloro-2-(4-(dimethylamino)phenyl)-3H-imid...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP2C9 after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224734BDBM50224734(2-(4-(6-chloro-2-(4-(dimethylamino)phenyl)-3H-imid...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP3A4 after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224758BDBM50224758(3-(3H-imidazo[4,5-b]pyridin-2-yl)-N,N-dimethylbenz...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224734BDBM50224734(2-(4-(6-chloro-2-(4-(dimethylamino)phenyl)-3H-imid...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP2D6 after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224739BDBM50224739(4-(3H-imidazo[4,5-c]pyridin-2-yl)-N,N-dimethylbenz...)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224743BDBM50224743(2-(3-methoxyphenyl)-3H-imidazo[4,5-b]pyridine | CH...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224746BDBM50224746(2-(4-(6,7-dimethoxyquinazolin-4-yl)piperazin-1-yl)...)
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224756BDBM50224756(3-(2-(4-(dimethylamino)phenyl)-3H-imidazo[4,5-b]py...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224757BDBM50224757(4-(6-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-2-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224741BDBM50224741(6,7-dimethoxy-4-(4-(1-phenylethyl)piperazin-1-yl)q...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045027BDBM50045027(CHEMBL543042 | CHEMBL236937 | 2-(2-Methoxy-phenyl)...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224755BDBM50224755(6,7-dimethoxy-4-(4-(2-phenoxyethyl)piperazin-1-yl)...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224732BDBM50224732(4-(4-(4-fluorobenzyl)piperazin-1-yl)-6,7-dimethoxy...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224747BDBM50224747(6,7-dimethoxy-4-(4-phenethylpiperazin-1-yl)quinazo...)
Affinity DataIC50: 7.60E+4nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224744BDBM50224744(2-(4-(6,7-dimethoxyquinazolin-4-yl)piperazin-1-yl)...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed