Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50022550
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM31340(CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant intracellular domain of erbB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM31340(CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human erbB2 intracellular domain transfected in mouse NIH3T3 cells assessed as potency reduction in autophosphorylation of the chimera ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM31340(CP-724714 | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of human recombinant intracellular domain of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed