Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 50021488
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM50225226(4-(2,4-dichlorophenoxy)-3-methoxybenzoic acid | CH...)
Affinity DataIC50:  475nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM50225224(4-(2,4-dichlorophenoxy)-3-hydroxybenzaldehyde | CH...)
Affinity DataIC50:  520nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM50225217(5-(chloromethyl)-2-(2,4-dichlorophenoxy)phenol | C...)
Affinity DataIC50:  850nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM50225221(2,3,6-trichloro-N-(4H-1,2,4-triazol-3-yl)benzamide...)
Affinity DataIC50:  1.06E+3nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM50225219(3-methoxy-4-phenoxybenzaldehyde | CHEMBL241453)
Affinity DataIC50:  1.31E+3nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM50225216(2-(2,4-dichlorophenoxy)-5-(hydroxymethyl)phenol | ...)
Affinity DataIC50:  1.36E+3nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM50225218(4-(chloromethyl)-2-methoxy-1-phenoxybenzene | CHEM...)
Affinity DataIC50:  1.94E+3nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM25406(4-(2,4-dichlorophenoxy)-3-hydroxybenzoic acid | CH...)
Affinity DataIC50:  2.59E+3nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM50225229(2-(5-mercapto-1,3,4-oxadiazol-2-yl)phenol | CHEMBL...)
Affinity DataIC50:  3.10E+3nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM50225227(2,4-dichloro-1-(4-(chloromethyl)-2-methoxyphenoxy)...)
Affinity DataIC50:  3.16E+3nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM50225228(3-hydroxy-4-phenoxybenzoic acid | CHEMBL241454)
Affinity DataIC50:  3.18E+3nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM50225220(CHEMBL559 | D-thyroxine | O-(4-hydroxy-3,5-diiodop...)
Affinity DataIC50:  7.17E+3nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM50225230(4-(2,4-dinitrophenoxy)-3-methoxybenzoic acid | CHE...)
Affinity DataIC50:  2.00E+4nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM50225222((4-(2,4-dinitrophenoxy)-3-methoxyphenyl)methanol |...)
Affinity DataIC50:  2.00E+4nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM50225231(3-methoxy-4-phenoxybenzoic acid | CHEMBL392872)
Affinity DataIC50:  4.10E+4nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM50225225(5-(hydroxymethyl)-2-phenoxyphenol | CHEMBL238590)
Affinity DataIC50:  4.50E+4nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM8726(5-chloro-2-(2,4-dichlorophenoxy)phenol | CHEMBL849...)
Affinity DataIC50:  5.35E+4nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM50225223(4-(2,4-dinitrophenoxy)-3-hydroxybenzaldehyde | CHE...)
Affinity DataIC50:  5.50E+4nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM8726(5-chloro-2-(2,4-dichlorophenoxy)phenol | CHEMBL849...)
Affinity DataKd:  1.44E+5nMpH: 4.4Assay Description:Binding affinity to transthyretin at pH 4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM50225229(2-(5-mercapto-1,3,4-oxadiazol-2-yl)phenol | CHEMBL...)
Affinity DataKd:  42nMpH: 4.4Assay Description:Binding affinity to transthyretin at pH 4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM50225216(2-(2,4-dichlorophenoxy)-5-(hydroxymethyl)phenol | ...)
Affinity DataKd:  0.300nMpH: 4.4Assay Description:Binding affinity to transthyretin at pH 4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM50225228(3-hydroxy-4-phenoxybenzoic acid | CHEMBL241454)
Affinity DataKd:  27nMpH: 4.4Assay Description:Binding affinity to transthyretin at pH 4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM50225217(5-(chloromethyl)-2-(2,4-dichlorophenoxy)phenol | C...)
Affinity DataKd:  5.70nMpH: 4.4Assay Description:Binding affinity to transthyretin at pH 4.4More data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM50225221(2,3,6-trichloro-N-(4H-1,2,4-triazol-3-yl)benzamide...)
Affinity DataKd:  120nMpH: 4.4Assay Description:Binding affinity to transthyretin at pH 4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM25406(4-(2,4-dichlorophenoxy)-3-hydroxybenzoic acid | CH...)
Affinity DataKd:  27nMpH: 4.4Assay Description:Binding affinity to transthyretin at pH 4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM50225224(4-(2,4-dichlorophenoxy)-3-hydroxybenzaldehyde | CH...)
Affinity DataKd:  13.9nMpH: 4.4Assay Description:Binding affinity to transthyretin at pH 4.4More data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM50225226(4-(2,4-dichlorophenoxy)-3-methoxybenzoic acid | CH...)
Affinity DataKd:  0.200nMpH: 4.4Assay Description:Binding affinity to transthyretin at pH 4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Institute Of Sciences

Curated by ChEMBL
LigandPNGBDBM50225219(3-methoxy-4-phenoxybenzaldehyde | CHEMBL241453)
Affinity DataKd:  88nMpH: 4.4Assay Description:Binding affinity to transthyretin at pH 4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed