Compile Data Set for Download or QSAR
maximum 50k data
Found 26 Enz. Inhib. hit(s) with all data for entry = 2401
TargetThymidine phosphorylase(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM20079(5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,...)
Affinity DataKi:  1.30nM ΔG°:  -52.8kJ/molepH: 6.4 T: 2°CAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM20061(5-Substituted-6-chlorouracil, 7a | 6-chloro-5-(cyc...)
Affinity DataKi:  200nM ΔG°:  -39.8kJ/molepH: 6.4 T: 2°CAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM20069(5-Substituted-6-chlorouracil, 10e | 6-chloro-5-(th...)
Affinity DataKi:  280nM ΔG°:  -38.9kJ/molepH: 6.4 T: 2°CAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM20065(5-Substituted-6-chlorouracil, 10a | 6-chloro-5-phe...)
Affinity DataKi:  400nM ΔG°:  -38.0kJ/molepH: 6.4 T: 2°CAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM20073(5-Substituted-6-chlorouracil, 13c | 6-chloro-5-[(1...)
Affinity DataKi:  410nM ΔG°:  -37.9kJ/molepH: 6.4 T: 2°CAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM20062(5-Substituted-6-chlorouracil, 7b | 6-chloro-5-(cyc...)
Affinity DataKi:  420nM ΔG°:  -37.9kJ/molepH: 6.4 T: 2°CAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM20064(5-Substituted-6-chlorouracil, 7d | 6-chloro-5-[(2E...)
Affinity DataKi:  490nM ΔG°:  -37.5kJ/molepH: 6.4 T: 2°CAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM20075(6-Fluoro-5-phenylpyrimidine-2,4(1H,3H)-dione, 21 |...)
Affinity DataKi:  500nM ΔG°:  -37.4kJ/molepH: 6.4 T: 2°CAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM20072(5-Substituted-6-chlorouracil, 13b | 5-[(1E)-but-1-...)
Affinity DataKi:  630nM ΔG°:  -36.8kJ/molepH: 6.4 T: 2°CAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM20068(5-Substituted-6-chlorouracil, 10d | 6-chloro-5-(4-...)
Affinity DataKi:  710nM ΔG°:  -36.5kJ/molepH: 6.4 T: 2°CAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM20056(5-Substituted-6-chlorouracil, 5c | 5-butyl-6-chlor...)
Affinity DataKi:  1.03E+3nM ΔG°:  -35.5kJ/molepH: 6.4 T: 2°CAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM20059(5-Substituted-6-chlorouracil, 5f | 6-chloro-5-hept...)
Affinity DataKi:  1.06E+3nM ΔG°:  -35.5kJ/molepH: 6.4 T: 2°CAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM20071(5-Substituted-6-chlorouracil, 13a | 6-chloro-5-[(1...)
Affinity DataKi:  1.17E+3nM ΔG°:  -35.2kJ/molepH: 6.4 T: 2°CAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM20076(6-Bromo-5-phenylpyrimidine-2,4(1H,3H)-dione, 23 | ...)
Affinity DataKi:  1.21E+3nM ΔG°:  -35.1kJ/molepH: 6.4 T: 2°CAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM20066(5-Substituted-6-chlorouracil, 10b | 6-chloro-5-(3,...)
Affinity DataKi:  1.74E+3nM ΔG°:  -34.2kJ/molepH: 6.4 T: 2°CAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM20058(5-Substituted-6-chlorouracil, 5e | 6-chloro-5-hexy...)
Affinity DataKi:  1.83E+3nM ΔG°:  -34.1kJ/molepH: 6.4 T: 2°CAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM20070(5-Substituted-6-chlorouracil, 10f | 6-chloro-5-(py...)
Affinity DataKi:  3.01E+3nM ΔG°:  -32.8kJ/molepH: 6.4 T: 2°CAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM20063(5-Substituted-6-chlorouracil, 7c | 6-chloro-5-(pro...)
Affinity DataKi:  3.34E+3nM ΔG°:  -32.5kJ/molepH: 6.4 T: 2°CAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM20057(5-Substituted-6-chlorouracil, 5d | 6-chloro-5-pent...)
Affinity DataKi:  3.67E+3nM ΔG°:  -32.3kJ/molepH: 6.4 T: 2°CAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM20067(5-Substituted-6-chlorouracil, 10c | 6-chloro-5-(na...)
Affinity DataKi:  4.59E+3nM ΔG°:  -31.7kJ/molepH: 6.4 T: 2°CAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM20060(5-Substituted-6-chlorouracil, 5g | 5-benzyl-6-chlo...)
Affinity DataKi:  4.65E+3nM ΔG°:  -31.7kJ/molepH: 6.4 T: 2°CAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM20055(5-Substituted-6-chlorouracil, 5b | 6-chloro-5-prop...)
Affinity DataKi:  5.81E+3nM ΔG°:  -31.1kJ/molepH: 6.4 T: 2°CAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM20054(5-Substituted-6-chlorouracil, 5a | 6-chloro-5-ethy...)
Affinity DataKi: >2.00E+4nM ΔG°: >-27.9kJ/molepH: 6.4 T: 2°CAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM20077(5-Phenyl-6-pyrrolidin-1-ylpyrimidine-2,4(1H,3H)-di...)
Affinity DataKi: >2.00E+4nM ΔG°: >-27.9kJ/molepH: 6.4 T: 2°CAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM20078(6-[(2-Aminoethyl)amino]-5-phenylpyrimidine-2,4(1H,...)
Affinity DataKi: >2.00E+4nM ΔG°: >-27.9kJ/molepH: 6.4 T: 2°CAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM20074(6-Methyl-5-phenylpyrimidine-2,4(1H,3H)-dione, 16 |...)
Affinity DataKi: >2.00E+4nM ΔG°: >-27.9kJ/molepH: 6.4 T: 2°CAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed