Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with all data for entry = 50037997
TargetBeta-secretase 1(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50226438((S)-5-((S)-1-carboxy-2-phenylethylamino)-4-((S)-2-...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM16047((4S)-4-[(2S)-2-[(2R,4S,5S)-5-[(2S)-2-[(2S)-2-[(4S)...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
TargetEndothiapepsin(Cryphonectria parasitica)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50226437(2-AMINO-6-(2-PHENYLETHYL)PYRIMIDIN-4(3H)-ONE | 2-a...)
Affinity DataKd:  2.20E+5nMAssay Description:Binding affinity to endothiapepsin by Biocore ISAMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50226437(2-AMINO-6-(2-PHENYLETHYL)PYRIMIDIN-4(3H)-ONE | 2-a...)
Affinity DataKd:  6.60E+5nMAssay Description:Binding affinity to BACE1 expressed in HEK293 cells by Biocore ISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50226439(2-amino-6-propylpyrimidin-4(3H)-one | CHEMBL235825)
Affinity DataKd:  4.45E+6nMAssay Description:Binding affinity to BACE1 expressed in HEK293 cells by Biocore ISAMore data for this Ligand-Target Pair