Affinity DataIC50: 6nMAssay Description:Displacement of [3H]LY354740 from rat recombinant mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Displacement of [3H]LY354740 from rat recombinant mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Antagonist activity at rat mGluR2 assessed as effect on (1S,3R)-ACPD-induced inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rat mGluR2 assessed as effect on (1S,3R)-ACPD-induced inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Antagonist activity at rat mGluR2 assessed as effect on (1S,3R)-ACPD-induced inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Antagonist activity at rat mGluR2 assessed as effect on (1S,3R)-ACPD-induced inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]LY354740 from rat recombinant mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Antagonist activity at rat mGluR2 assessed as effect on (1S,3R)-ACPD-induced inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Antagonist activity at rat mGluR2 assessed as effect on (1S,3R)-ACPD-induced inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Antagonist activity at rat mGluR2 assessed as effect on (1S,3R)-ACPD-induced inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Antagonist activity at rat mGluR2 assessed as effect on (1S,3R)-ACPD-induced inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Antagonist activity at rat mGluR2 assessed as effect on (1S,3R)-ACPD-induced inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Displacement of [3H]LY354740 from rat recombinant mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]LY354740 from rat recombinant mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]LY354740 from rat recombinant mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Displacement of [3H]LY354740 from rat recombinant mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Displacement of [3H]LY354740 from rat recombinant mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Displacement of [3H]LY354740 from rat mGluR2More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Displacement of [3H]LY354740 from rat recombinant mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Displacement of [3H]LY354740 from rat recombinant mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Displacement of [3H]LY354740 from rat recombinant mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Displacement of [3H]LY354740 from rat recombinant mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Displacement of [3H]LY354740 from rat recombinant mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 98nMAssay Description:Displacement of [3H]LY354740 from rat recombinant mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 98nMAssay Description:Displacement of [3H]LY354740 from rat recombinant mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Displacement of [3H]LY354740 from rat recombinant mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Displacement of [3H]LY354740 from rat recombinant mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 378nMAssay Description:Displacement of [3H]LY354740 from rat recombinant mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 730nMAssay Description:Displacement of [3H]LY354740 from rat recombinant mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Displacement of [3H]-L-AP4 from rat mGluR8More data for this Ligand-Target Pair
Affinity DataIC50: 6.40E+3nMAssay Description:Displacement of [3H]LY354740 from rat mGluR2More data for this Ligand-Target Pair