Compile Data Set for Download or QSAR
maximum 50k data
Found 47 Enz. Inhib. hit(s) with all data for entry = 50022372
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50198149((S)-1-(4-(1-(3,5-bis(trifluoromethyl)benzylamino)-...)
Affinity DataIC50:  0.430nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50198109((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-acetam...)
Affinity DataIC50:  1.80nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50212127((1S,3R)-1-cyclopropyl-N-{[3-fluoro-5-(trifluoromet...)
Affinity DataIC50:  1.90nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50212136((1S,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)
Affinity DataIC50:  3.10nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50212122((1R,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)
Affinity DataIC50:  3.5nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50198123((S)-methyl 4-(1-(3,5-bis(trifluoromethyl)benzylami...)
Affinity DataIC50:  3.5nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50212128((1R,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)
Affinity DataIC50:  3.90nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50212140((1S,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)
Affinity DataIC50:  4nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50212145((1S,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}...)
Affinity DataIC50:  7.60nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50212139((1R,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}...)
Affinity DataIC50:  8nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50212141((1S,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}...)
Affinity DataIC50:  9nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50212130((1R,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}...)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50198135((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-aminot...)
Affinity DataIC50:  13.3nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50198120((R)-tert-butyl 4-(1-(3,5-bis(trifluoromethyl)benzy...)
Affinity DataIC50:  13.3nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50234500(CHEMBL252412 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50198133((S)-tert-butyl 4-(1-(3,5-bis(trifluoromethyl)benzy...)
Affinity DataIC50:  14.3nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50212138((1S,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}...)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50212124((1R,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}...)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50212132((1S,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}...)
Affinity DataIC50:  20nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50234494(CHEMBL400517 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  25nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50212137((1R,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}...)
Affinity DataIC50:  28nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50234491(CHEMBL252611 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  28nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50198144((R)-1-(4-(1-(3,5-bis(trifluoromethyl)benzylamino)-...)
Affinity DataIC50:  30nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50187033((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(piper...)
Affinity DataIC50:  39nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50198113((R)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-acetam...)
Affinity DataIC50:  42nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50212143((1R,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)
Affinity DataIC50:  67nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50191798(CHEMBL215654 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  98nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50234498(CHEMBL252815 | N-(3,5-bis(trifluoromethyl)benzyl)-...)
Affinity DataIC50:  126nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50191816(CHEMBL409162 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  173nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50187053((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(4-fluoro...)
Affinity DataIC50:  175nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50234493(CHEMBL252208 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  193nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50234497(CHEMBL400516 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  204nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50187048((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-phenyl-2-...)
Affinity DataIC50:  219nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50234496((R)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-aminot...)
Affinity DataIC50:  229nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50234492(CHEMBL252206 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  231nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50234499(CHEMBL252813 | N-(3,5-bis(trifluoromethyl)benzyl)-...)
Affinity DataIC50:  280nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50234495(CHEMBL252814 | N-(3,5-bis(trifluoromethyl)benzyl)-...)
Affinity DataIC50:  285nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50187057((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(azepa...)
Affinity DataIC50:  400nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50187031((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(dimet...)
Affinity DataIC50:  424nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50191826(CHEMBL378449 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  570nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50234490(CHEMBL399717 | N-(3,5-bis(trifluoromethyl)benzyl)-...)
Affinity DataIC50:  642nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50187054((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(4-met...)
Affinity DataIC50:  756nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50187037((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(dimet...)
Affinity DataIC50:  770nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50187052((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-phenyl-2-...)
Affinity DataIC50:  822nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50187030((2S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(2-me...)
Affinity DataIC50:  838nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50187041((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(dimet...)
Affinity DataIC50:  865nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50187045((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(dimet...)
Affinity DataIC50:  1.00E+3nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed