Compile Data Set for Download or QSAR
maximum 50k data
Found 60 Enz. Inhib. hit(s) with all data for entry = 50022373
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234509(4-(2-(5-chloro-1-methyl-1H-imidazol-4-yl)ethylamin...)
Affinity DataIC50:  38nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234523(4-(2-(5-chloro-1,2-dimethyl-1H-imidazol-4-yl)ethyl...)
Affinity DataIC50:  66nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234524(CHEMBL256908 | ethyl 1-(2-(3-(4-methyl-6-morpholin...)
Affinity DataIC50:  68nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234518(4-(2-(5-bromo-1-methyl-1H-imidazol-4-yl)ethylamino...)
Affinity DataIC50:  75nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234506(4-(2-(4-bromo-1H-pyrazol-1-yl)ethylamino)-3-(4-met...)
Affinity DataIC50:  82nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234525(4-(2-(5-chloro-1-(2-fluoroethyl)-1H-imidazol-4-yl)...)
Affinity DataIC50:  82nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234505(4-(2-(5-chloro-1-ethyl-1H-imidazol-4-yl)ethylamino...)
Affinity DataIC50:  83nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234522(CHEMBL256909 | methyl 1-(2-(3-(4-methyl-6-morpholi...)
Affinity DataIC50:  91nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234510(4-(2-(4-chloro-3-methyl-1H-pyrazol-1-yl)ethylamino...)
Affinity DataIC50:  96nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234512(4-(2-(4-bromo-3-(hydroxymethyl)-1H-pyrazol-1-yl)et...)
Affinity DataIC50:  96nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM27879(4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234527(4-(2-(4-bromo-3-methyl-1H-pyrazol-1-yl)ethylamino)...)
Affinity DataIC50:  110nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM27879(4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-...)
Affinity DataIC50:  110nMAssay Description:Inhibition of IGF1R expressed in SAL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234521(4-(2-(4-methyl-1H-pyrazol-1-yl)ethylamino)-3-(4-me...)
Affinity DataIC50:  110nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234513(4-(2-(4-chloro-1H-pyrazol-1-yl)ethylamino)-3-(4-me...)
Affinity DataIC50:  120nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234506(4-(2-(4-bromo-1H-pyrazol-1-yl)ethylamino)-3-(4-met...)
Affinity DataIC50:  144nMAssay Description:Inhibition of IGF1R expressed in SAL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234519(4-(2-(2,5-dichloro-1-methyl-1H-imidazol-4-yl)ethyl...)
Affinity DataIC50:  160nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234529(4-(2-(5-bromo-1-ethyl-1H-imidazol-4-yl)ethylamino)...)
Affinity DataIC50:  172nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234503(4-(2-(1-methyl-1H-imidazol-4-yl)ethylamino)-3-(4-m...)
Affinity DataIC50:  190nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234527(4-(2-(4-bromo-3-methyl-1H-pyrazol-1-yl)ethylamino)...)
Affinity DataIC50:  197nMAssay Description:Inhibition of IGF1R expressed in SAL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234528(4-(2-(1-ethyl-5-ethynyl-1H-imidazol-4-yl)ethylamin...)
Affinity DataIC50:  243nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234523(4-(2-(5-chloro-1,2-dimethyl-1H-imidazol-4-yl)ethyl...)
Affinity DataIC50:  266nMAssay Description:Inhibition of IGF1R expressed in SAL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234508(4-(2-(5-methyl-1H-pyrazol-1-yl)ethylamino)-3-(4-me...)
Affinity DataIC50:  270nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234529(4-(2-(5-bromo-1-ethyl-1H-imidazol-4-yl)ethylamino)...)
Affinity DataIC50:  284nMAssay Description:Inhibition of IGF1R expressed in SAL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234501(4-(2-(5-chloro-1-(2-methoxyethyl)-1H-imidazol-4-yl...)
Affinity DataIC50:  290nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234502(4-(2-(3-methyl-1H-pyrazol-1-yl)ethylamino)-3-(4-me...)
Affinity DataIC50:  290nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234510(4-(2-(4-chloro-3-methyl-1H-pyrazol-1-yl)ethylamino...)
Affinity DataIC50:  292nMAssay Description:Inhibition of IGF1R expressed in SAL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234519(4-(2-(2,5-dichloro-1-methyl-1H-imidazol-4-yl)ethyl...)
Affinity DataIC50:  306nMAssay Description:Inhibition of IGF1R expressed in SAL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234526(4-(2-(1H-pyrazol-1-yl)ethylamino)-3-(4-methyl-6-mo...)
Affinity DataIC50:  330nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234509(4-(2-(5-chloro-1-methyl-1H-imidazol-4-yl)ethylamin...)
Affinity DataIC50:  336nMAssay Description:Inhibition of IGF1R expressed in SAL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234518(4-(2-(5-bromo-1-methyl-1H-imidazol-4-yl)ethylamino...)
Affinity DataIC50:  343nMAssay Description:Inhibition of IGF1R expressed in SAL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234517(4-(2-(5-chloro-1-isopropyl-1H-imidazol-4-yl)ethyla...)
Affinity DataIC50:  360nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234520(4-(2-(1-isopropyl-1H-imidazol-4-yl)ethylamino)-3-(...)
Affinity DataIC50:  360nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234520(4-(2-(1-isopropyl-1H-imidazol-4-yl)ethylamino)-3-(...)
Affinity DataIC50:  365nMAssay Description:Inhibition of IGF1R expressed in SAL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234513(4-(2-(4-chloro-1H-pyrazol-1-yl)ethylamino)-3-(4-me...)
Affinity DataIC50:  376nMAssay Description:Inhibition of IGF1R expressed in SAL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234521(4-(2-(4-methyl-1H-pyrazol-1-yl)ethylamino)-3-(4-me...)
Affinity DataIC50:  397nMAssay Description:Inhibition of IGF1R expressed in SAL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234502(4-(2-(3-methyl-1H-pyrazol-1-yl)ethylamino)-3-(4-me...)
Affinity DataIC50:  422nMAssay Description:Inhibition of IGF1R expressed in SAL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234525(4-(2-(5-chloro-1-(2-fluoroethyl)-1H-imidazol-4-yl)...)
Affinity DataIC50:  451nMAssay Description:Inhibition of IGF1R expressed in SAL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234505(4-(2-(5-chloro-1-ethyl-1H-imidazol-4-yl)ethylamino...)
Affinity DataIC50:  469nMAssay Description:Inhibition of IGF1R expressed in SAL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234504(4-(2-(4-bromo-5-(hydroxymethyl)-1H-pyrazol-1-yl)et...)
Affinity DataIC50:  470nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234511(4-(2-(1-ethyl-1H-imidazol-4-yl)ethylamino)-3-(4-me...)
Affinity DataIC50:  480nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234515(4-(2-(4-bromo-5-methyl-1H-pyrazol-1-yl)ethylamino)...)
Affinity DataIC50:  510nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234503(4-(2-(1-methyl-1H-imidazol-4-yl)ethylamino)-3-(4-m...)
Affinity DataIC50:  521nMAssay Description:Inhibition of IGF1R expressed in SAL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234524(CHEMBL256908 | ethyl 1-(2-(3-(4-methyl-6-morpholin...)
Affinity DataIC50:  531nMAssay Description:Inhibition of IGF1R expressed in SAL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234508(4-(2-(5-methyl-1H-pyrazol-1-yl)ethylamino)-3-(4-me...)
Affinity DataIC50:  542nMAssay Description:Inhibition of IGF1R expressed in SAL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234507(4-(2-(1-(2-methoxyethyl)-1H-imidazol-4-yl)ethylami...)
Affinity DataIC50:  550nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234511(4-(2-(1-ethyl-1H-imidazol-4-yl)ethylamino)-3-(4-me...)
Affinity DataIC50:  583nMAssay Description:Inhibition of IGF1R expressed in SAL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234526(4-(2-(1H-pyrazol-1-yl)ethylamino)-3-(4-methyl-6-mo...)
Affinity DataIC50:  613nMAssay Description:Inhibition of IGF1R expressed in SAL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234501(4-(2-(5-chloro-1-(2-methoxyethyl)-1H-imidazol-4-yl...)
Affinity DataIC50:  622nMAssay Description:Inhibition of IGF1R expressed in SAL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50234514(4-(2-(4-chloro-5-methyl-1H-pyrazol-1-yl)ethylamino...)
Affinity DataIC50:  630nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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