Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50041709
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131433BDBM50131433(4-(2-{4-[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human ERG channel in HEK293 cells by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334150BDBM50334150(1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)...)
Affinity DataIC50: 3.02nMAssay Description:Inhibition of human ERG channel in HEK293 cells by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 24064BDBM24064(N-[(4R)-1'-[(2R)-6-cyano-1,2,3,4-tetrahydronaphtha...)
Affinity DataIC50: 21.4nMAssay Description:Inhibition of human ERG channel in HEK293 cells by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50117930BDBM50117930(N-(4-{1-[2-(6-Methyl-pyridin-2-yl)-ethyl]-piperidi...)
Affinity DataIC50: 22.9nMAssay Description:Inhibition of human ERG channel in HEK293 cells by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50117925BDBM50117925(1-(4-fluorobenzyl)-N-(piperidin-4-yl)-1H-benzo[d]i...)
Affinity DataIC50: 27.5nMAssay Description:Inhibition of human ERG channel in HEK293 cells by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017705BDBM50017705(1-(1-(4-(4-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetra...)
Affinity DataIC50: 32.4nMAssay Description:Inhibition of human ERG channel in HEK293 cells by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031720BDBM50031720((Dofetilide) N-[4-(2-{[2-(4-Methanesulfonylamino-p...)
Affinity DataIC50: 49.0nMAssay Description:Inhibition of human ERG channel in HEK293 cells by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241107BDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataIC50: 57.5nMAssay Description:Inhibition of human ERG channel in HEK293 cells by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289291BDBM50289291([10-(4-Methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-...)
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of human ERG channel in HEK293 cells by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240701BDBM50240701(CHEMBL1125 | 2-Methyl-10-piperazin-1-yl-4H-3-thia-...)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of human ERG channel in HEK293 cells by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50413638BDBM50413638(PILSICAINIDE HYDROCHLORIDE | PILSICAINIDE)
Affinity DataIC50: 2.04E+4nMAssay Description:Inhibition of human ERG channel in HEK293 cells by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50026752BDBM50026752(4-Ethoxycarbonyl-1-methyl-4-phenyl-piperidinium | ...)
Affinity DataIC50: 7.59E+4nMAssay Description:Inhibition of human ERG channel in HEK293 cells by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14777BDBM14777(CHEMBL779 | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-m...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERG channel in HEK293 cells by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50413637BDBM50413637(METHYLECGONIDINE)
Affinity DataIC50: 1.70E+5nMAssay Description:Inhibition of human ERG channel in HEK293 cells by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031299BDBM50031299(CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...)
Affinity DataIC50: 2.29E+5nMAssay Description:Inhibition of human ERG channel in HEK293 cells by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82070BDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataIC50: 2.45E+5nMAssay Description:Inhibition of human ERG channel in HEK293 cells by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017662BDBM50017662(CHEMBL79 | N-(2,6-dimethylphenyl)-N(2),N(2)-diethy...)
Affinity DataIC50: 2.63E+5nMAssay Description:Inhibition of human ERG channel in HEK293 cells by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50021437BDBM50021437(Phenylethylbarbituric Acid | Phenobarbital | Pheno...)
Affinity DataIC50: 3.02E+6nMAssay Description:Inhibition of human ERG channel in HEK293 cells by voltage-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed