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Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 5681
TargetProtein kinase C delta type(Human)
National Cancer Institute-Bethesda

LigandPNGBDBM92596(Sapintoxin D)
Affinity DataKi:  0.140nM ΔG°:  -54.9kJ/molepH: 7.4 T: 18°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetProtein kinase C delta type(Human)
National Cancer Institute-Bethesda

LigandPNGBDBM50107112((Z) 2,2-Dimethyl-propionic acid 2-hydroxymethyl-4-...)
Affinity DataKi:  1.16nM ΔG°:  -49.8kJ/molepH: 7.4 T: 18°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein kinase C delta type(Human)
National Cancer Institute-Bethesda

LigandPNGBDBM92595(DAG-lactone (130C045))
Affinity DataKi:  1.54nM ΔG°:  -49.1kJ/molepH: 7.4 T: 18°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase MRCK alpha(Human)
National Cancer Institute-Bethesda

LigandPNGBDBM92596(Sapintoxin D)
Affinity DataKi:  5.90nM ΔG°:  -45.9kJ/molepH: 7.4 T: 18°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetProtein kinase C delta type(Human)
National Cancer Institute-Bethesda

LigandPNGBDBM50015677((S)-1-hydroxymethyl-2-octanoyloxy-ethyl ester | 1,...)
Affinity DataKi:  6.80nM ΔG°:  -45.5kJ/molepH: 7.4 T: 18°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase MRCK beta(Human)
National Cancer Institute-Bethesda

LigandPNGBDBM92596(Sapintoxin D)
Affinity DataKi:  12.6nM ΔG°:  -44.0kJ/molepH: 7.4 T: 18°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetProtein kinase C alpha type(Human)
National Cancer Institute-Bethesda

LigandPNGBDBM92596(Sapintoxin D)
Affinity DataKi:  18.2nM ΔG°:  -43.1kJ/molepH: 7.4 T: 18°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetProtein kinase C alpha type(Human)
National Cancer Institute-Bethesda

LigandPNGBDBM50107112((Z) 2,2-Dimethyl-propionic acid 2-hydroxymethyl-4-...)
Affinity DataKi:  402nM ΔG°:  -35.6kJ/molepH: 7.4 T: 18°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase MRCK alpha(Human)
National Cancer Institute-Bethesda

LigandPNGBDBM50107112((Z) 2,2-Dimethyl-propionic acid 2-hydroxymethyl-4-...)
Affinity DataKi:  1.03E+3nM ΔG°:  -33.4kJ/molepH: 7.4 T: 18°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase MRCK beta(Human)
National Cancer Institute-Bethesda

LigandPNGBDBM50107112((Z) 2,2-Dimethyl-propionic acid 2-hydroxymethyl-4-...)
Affinity DataKi:  1.07E+3nM ΔG°:  -33.3kJ/molepH: 7.4 T: 18°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase MRCK alpha(Human)
National Cancer Institute-Bethesda

LigandPNGBDBM50015677((S)-1-hydroxymethyl-2-octanoyloxy-ethyl ester | 1,...)
Affinity DataKi:  2.82E+3nM ΔG°:  -30.9kJ/molepH: 7.4 T: 18°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein kinase C alpha type(Human)
National Cancer Institute-Bethesda

LigandPNGBDBM92595(DAG-lactone (130C045))
Affinity DataKi:  4.20E+3nM ΔG°:  -30.0kJ/molepH: 7.4 T: 18°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein kinase C alpha type(Human)
National Cancer Institute-Bethesda

LigandPNGBDBM50015677((S)-1-hydroxymethyl-2-octanoyloxy-ethyl ester | 1,...)
Affinity DataKi:  6.70E+3nM ΔG°:  -28.8kJ/molepH: 7.4 T: 18°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase MRCK beta(Human)
National Cancer Institute-Bethesda

LigandPNGBDBM50015677((S)-1-hydroxymethyl-2-octanoyloxy-ethyl ester | 1,...)
Affinity DataKi:  6.96E+3nM ΔG°:  -28.7kJ/molepH: 7.4 T: 18°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase MRCK alpha(Human)
National Cancer Institute-Bethesda

LigandPNGBDBM92595(DAG-lactone (130C045))
Affinity DataKi:  2.26E+4nM ΔG°:  -25.9kJ/molepH: 7.4 T: 18°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase MRCK beta(Human)
National Cancer Institute-Bethesda

LigandPNGBDBM92595(DAG-lactone (130C045))
Affinity DataKi:  2.26E+4nM ΔG°:  -25.9kJ/molepH: 7.4 T: 18°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein kinase C delta type(Human)
National Cancer Institute-Bethesda

LigandPNGBDBM92594(Phorbol ester (PDBU))
Affinity DataKd:  0.177nMpH: 7.4 T: 18°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein kinase C alpha type(Human)
National Cancer Institute-Bethesda

LigandPNGBDBM92594(Phorbol ester (PDBU))
Affinity DataKd:  3.40nMpH: 7.4 T: 18°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase MRCK beta(Human)
National Cancer Institute-Bethesda

LigandPNGBDBM92594(Phorbol ester (PDBU))
Affinity DataKd:  17nMpH: 7.4 T: 18°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase MRCK alpha(Human)
National Cancer Institute-Bethesda

LigandPNGBDBM92594(Phorbol ester (PDBU))
Affinity DataKd:  10.3nMpH: 7.4 T: 18°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed