Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50038086
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029559BDBM50029559(L-686708 | MK-591 | 3-[3-tert-Butylsulfanyl-1-(4-c...)
Affinity DataIC50: 1.60nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235083BDBM50235083(CHEMBL541915 | CHEMBL401667 | CHEMBL558778 | pyrid...)
Affinity DataIC50: 2.40nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235116BDBM50235116(2-(1-phenylcyclopentyl)-4-(quinolin-2-ylmethoxy)ph...)
Affinity DataIC50: 2.40nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235083BDBM50235083(CHEMBL541915 | CHEMBL401667 | CHEMBL558778 | pyrid...)
Affinity DataIC50: 2.5nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235107BDBM50235107(2-((4-((1,6-dihydropyridin-3-yl)methoxy)-3-(1-phen...)
Affinity DataIC50: 2.5nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235083BDBM50235083(CHEMBL541915 | CHEMBL401667 | CHEMBL558778 | pyrid...)
Affinity DataIC50: 2.80nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235117BDBM50235117(4-(2-(2-phenylbicyclo[2.2.1]heptan-2-yl)-4-(quinol...)
Affinity DataIC50: 3.5nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235087BDBM50235087(ethyl 4-(2-(2-phenylbicyclo[2.2.1]heptan-2-yl)-4-(...)
Affinity DataIC50: 3.70nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235115BDBM50235115(methyl 2-(2-(1-phenylcyclohexyl)-4-(quinolin-2-ylm...)
Affinity DataIC50: 3.70nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235110BDBM50235110(2-((3-(2-phenylbicyclo[2.2.1]heptan-2-yl)-4-(pyrid...)
Affinity DataIC50: 4.10nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235102BDBM50235102(2-((2-(1-phenylcyclohexyl)-4-(quinolin-2-ylmethoxy...)
Affinity DataIC50: 4.20nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235091BDBM50235091(2-((2-(1-phenylcyclopentyl)-4-(quinolin-2-ylmethox...)
Affinity DataIC50: 4.5nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235106BDBM50235106(5-((3-(2-phenylbicyclo[2.2.1]heptan-2-yl)-4-(pyrid...)
Affinity DataIC50: 4.90nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235094BDBM50235094(methyl 2-(2-(2-phenylbicyclo[2.2.1]heptan-2-yl)-4-...)
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235089BDBM50235089(2-((4-(2-(methylsulfonyl)ethoxy)-3-(2-phenylbicycl...)
Affinity DataIC50: 5.5nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235088BDBM50235088(methyl 2-(2-phenylbicyclo[2.2.1]heptan-2-yl)-4-(qu...)
Affinity DataIC50: 5.60nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235109BDBM50235109(2-((4-butoxy-3-(2-phenylbicyclo[2.2.1]heptan-2-yl)...)
Affinity DataIC50: 6nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235084BDBM50235084(N,N-dimethyl-2-(2-(2-phenylbicyclo[2.2.1]heptan-2-...)
Affinity DataIC50: 6.5nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235101BDBM50235101(2-((3-(2-phenylbicyclo[2.2.1]heptan-2-yl)-4-(pyrid...)
Affinity DataIC50: 7.60nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235085BDBM50235085(2-((4-(benzyloxy)-3-(2-phenylbicyclo[2.2.1]heptan-...)
Affinity DataIC50: 8.60nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235105BDBM50235105(2-((4-methoxy-3-(2-phenylbicyclo[2.2.1]heptan-2-yl...)
Affinity DataIC50: 8.60nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235104BDBM50235104(methyl 2-(2-(1-phenylcyclopentyl)-4-(quinolin-2-yl...)
Affinity DataIC50: 9.30nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235080BDBM50235080(2-(2-phenylbicyclo[2.2.1]heptan-2-yl)-4-(quinolin-...)
Affinity DataIC50: 12.4nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235090BDBM50235090(2-(2-phenylbicyclo[2.2.1]heptan-2-yl)-4-(quinolin-...)
Affinity DataIC50: 13.2nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235095BDBM50235095(2-(2-(2-phenylbicyclo[2.2.1]heptan-2-yl)-4-(quinol...)
Affinity DataIC50: 14nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235099BDBM50235099(2-((2-(2-phenylbicyclo[2.2.1]heptan-2-yl)-4-(pyrid...)
Affinity DataIC50: 18.3nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235082BDBM50235082(2-(1-phenylcyclopentyl)-4-(quinolin-2-ylmethoxy)ph...)
Affinity DataIC50: 22nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235118BDBM50235118(methyl 2-(3-(2-phenylbicyclo[2.2.1]heptan-2-yl)-4-...)
Affinity DataIC50: 94nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235098BDBM50235098(2-(4-(2-(4-(quinolin-2-ylmethoxy)phenyl)bicyclo[2....)
Affinity DataIC50: 98nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235093BDBM50235093(2-((4-(2-(4-(quinolin-2-ylmethoxy)phenyl)bicyclo[2...)
Affinity DataIC50: 127nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235114BDBM50235114(2-((2-(2-phenylbicyclo[2.2.1]heptan-2-yl)-4-(pyrid...)
Affinity DataIC50: 134nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235092BDBM50235092(4-(2-(4-(quinolin-2-ylmethoxy)phenyl)bicyclo[2.2.1...)
Affinity DataIC50: 145nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235097BDBM50235097(3-(2-phenylbicyclo[2.2.1]heptan-2-yl)-4-(pyridin-2...)
Affinity DataIC50: 181nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235113BDBM50235113(methyl 2-(4-(2-(4-(quinolin-2-ylmethoxy)phenyl)bic...)
Affinity DataIC50: 182nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235108BDBM50235108(2-(4-{2-[4-(2-hydroxy-ethoxy)-phenyl]-bicyclo[2.2....)
Affinity DataIC50: 387nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235096BDBM50235096(methyl 2-(2-(2-phenylbicyclo[2.2.1]heptan-2-yl)-5-...)
Affinity DataIC50: 776nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235081BDBM50235081(2-(2-phenylbicyclo[2.2.1]heptan-2-yl)-5-(quinolin-...)
Affinity DataIC50: 980nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235111BDBM50235111(2-(2-phenylbicyclo[2.2.1]heptan-2-yl)benzene-1,4-d...)
Affinity DataIC50: 2.07E+3nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235100BDBM50235100(2-(3-(2-phenylbicyclo[2.2.1]heptan-2-yl)-4-(quinol...)
Affinity DataIC50: 3.16E+3nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235086BDBM50235086(2-(2-(2-phenylbicyclo[2.2.1]heptan-2-yl)-5-(quinol...)
Affinity DataIC50: 3.60E+3nMAssay Description:Displacement of [125I]L-691831 from FLAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235090BDBM50235090(2-(2-phenylbicyclo[2.2.1]heptan-2-yl)-4-(quinolin-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of 5LOXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235094BDBM50235094(methyl 2-(2-(2-phenylbicyclo[2.2.1]heptan-2-yl)-4-...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of 5LOXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235098BDBM50235098(2-(4-(2-(4-(quinolin-2-ylmethoxy)phenyl)bicyclo[2....)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of 5LOXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50235108BDBM50235108(2-(4-{2-[4-(2-hydroxy-ethoxy)-phenyl]-bicyclo[2.2....)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of 5LOXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed