Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 2468
LigandPNGBDBM20971(2-Arylamino-4-alkyloxypyridine, 13 | 3,6-dimethyl-...)
Affinity DataIC50:  3.70nMpH: 7.0 T: 22°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

LigandPNGBDBM20966(2-Aryloxy-4-alkylaminopyridine, 3a | 3,6-dimethyl-...)
Affinity DataIC50:  5.10nMpH: 7.0 T: 22°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM20968(2-(4-bromo-2,6-dimethylphenoxy)-3,6-dimethyl-N-(pe...)
Affinity DataIC50:  5.60nMpH: 7.0 T: 22°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM20969(2-Aryloxy-4-alkylaminopyridine, 5a | methyl 2-(4-c...)
Affinity DataIC50:  6.40nMpH: 7.0 T: 22°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

LigandPNGBDBM20933(3,6-dimethyl-4-(pentan-3-yloxy)-2-(2,4,6-trimethyl...)
Affinity DataIC50:  6.80nMpH: 7.0 T: 22°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM20967(2-(4-chloro-2,6-dimethylphenoxy)-3,6-dimethyl-N-(p...)
Affinity DataIC50:  7.20nMpH: 7.0 T: 22°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM20970(2-(4-chloro-2,6-dimethylphenoxy)-4-{[(2S)-1-hydrox...)
Affinity DataIC50:  31nMpH: 7.0 T: 22°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

LigandPNGBDBM20972(2,4-diaminopyridine, 16 | 3,6-dimethyl-4-N-(pentan...)
Affinity DataIC50:  750nMpH: 7.0 T: 22°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed