Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50022468
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235550(1-(4-(5-((4-aminocyclohexylidene)methyl)pyrrolo[1,...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235540(2,6-difluoro-N-(3-fluoro-4-(5-methyl-6-(2-(4-methy...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235572(CHEMBL400332 | N-(4-(6-(3-(dimethylamino)propoxy)-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235548(CHEMBL254280 | N1-(4-(6-(3-(dimethylamino)propoxy)...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235547(1-(4-(5-(((3R,4R)-4-amino-3-hydroxypiperidin-1-yl)...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235565(2,5-difluoro-N-(3-fluoro-4-(5-methyl-6-(2-(4-methy...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235573(CHEMBL399698 | N1-(3-fluoro-4-(5-methyl-6-(2-(4-me...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235556(1-(4-(6-(3-(dimethylamino)propoxy)-5-methylpyrrolo...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235544(1-(4-(5-((4-aminopiperidin-1-yl)methyl)pyrrolo[1,2...)
Affinity DataIC50:  45nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235567(1-(3-fluoro-4-(5-methyl-6-(2-(4-methylpiperazin-1-...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235558(5-chloro-2-fluoro-N-(3-fluoro-4-(5-methyl-6-(2-(4-...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235575(CHEMBL253222 | N-(4-(6-(3-(dimethylamino)propoxy)-...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235543(2-fluoro-N-(3-fluoro-4-(5-methyl-6-(2-(4-methylpip...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235546(3-acetyl-N-(3-fluoro-4-(5-methyl-6-(2-(4-methylpip...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235571(2-fluoro-N-(3-fluoro-4-(5-methyl-6-(2-(4-methylpip...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235561(CHEMBL401344 | N1-(3-fluoro-4-(5-methyl-6-(2-morph...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235563(CHEMBL254907 | N1-(4-(6-(2-(dimethylamino)ethoxy)-...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235545(1-(3-fluoro-4-(5-((piperidin-4-ylamino)methyl)pyrr...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235554(1-(4-(6-(2-(dimethylamino)ethoxy)-5-methylpyrrolo[...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235555(CHEMBL251980 | N-(3-fluoro-4-(5-methyl-6-(2-(4-met...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235553(1-(4-(5-((3-(aminomethyl)azetidin-1-yl)methyl)pyrr...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235559(CHEMBL399674 | N-(3-fluoro-4-(5-methyl-6-(2-(4-met...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235549((S)-1-(4-(5-((3-aminopyrrolidin-1-yl)methyl)pyrrol...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHigh affinity nerve growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235544(1-(4-(5-((4-aminopiperidin-1-yl)methyl)pyrrolo[1,2...)
Affinity DataIC50:  200nMAssay Description:Inhibition of TrkAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235564(1-(3-fluoro-4-(5-phenylpyrrolo[1,2-f][1,2,4]triazi...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235570(1-(3-fluoro-4-(5-(piperazin-1-ylmethyl)pyrrolo[1,2...)
Affinity DataIC50:  410nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235551((R)-1-(4-(5-((3-aminopyrrolidin-1-yl)methyl)pyrrol...)
Affinity DataIC50:  440nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235562(1-(4-(5-((4-acetamidopiperidin-1-yl)methyl)pyrrolo...)
Affinity DataIC50:  440nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235552(2-fluoro-N-(3-fluoro-4-(5-methyl-6-(2-morpholinoet...)
Affinity DataIC50:  510nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235568(2-fluoro-N-(3-fluoro-4-(5-methylpyrrolo[1,2-f][1,2...)
Affinity DataIC50:  760nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235542(CHEMBL253223 | N1-(3-fluoro-4-(5-methylpyrrolo[1,2...)
Affinity DataIC50:  780nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235541(1-(3-fluoro-4-(5-((4-methylpiperazin-1-yl)methyl)p...)
Affinity DataIC50:  860nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235560(1-(3-fluoro-4-(5-((4-hydroxypiperidin-1-yl)methyl)...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235569(1-(3-fluoro-4-(5-(morpholinomethyl)pyrrolo[1,2-f][...)
Affinity DataIC50:  990nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235566(1-(4-(5-((4-(aminomethyl)piperidin-1-yl)methyl)pyr...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235557(1-(4-(5-((3-aminopropylamino)methyl)pyrrolo[1,2-f]...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235574(1-(4-(5-chloropyrrolo[1,2-f][1,2,4]triazin-4-yloxy...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235544(1-(4-(5-((4-aminopiperidin-1-yl)methyl)pyrrolo[1,2...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of lckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235544(1-(4-(5-((4-aminopiperidin-1-yl)methyl)pyrrolo[1,2...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInsulin-like growth factor 1 receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235544(1-(4-(5-((4-aminopiperidin-1-yl)methyl)pyrrolo[1,2...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235544(1-(4-(5-((4-aminopiperidin-1-yl)methyl)pyrrolo[1,2...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235544(1-(4-(5-((4-aminopiperidin-1-yl)methyl)pyrrolo[1,2...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInsulin receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235544(1-(4-(5-((4-aminopiperidin-1-yl)methyl)pyrrolo[1,2...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of InsRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMAP kinase-activated protein kinase 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50235544(1-(4-(5-((4-aminopiperidin-1-yl)methyl)pyrrolo[1,2...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed