Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 3275
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30300BDBM30300(indole-based 7-membered lactam, 25a)
Affinity DataIC50: 29nMAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30302BDBM30302(indole-based 7-membered lactam, 25b)
Affinity DataIC50: 35nMAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30303BDBM30303(indole-based 7-membered lactam, 25c)
Affinity DataIC50: 52nMAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30279BDBM30279(indole-based 6-membered lactam, 3b)
Affinity DataIC50: 140nMpH: 7.6 T: 2°CAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30288BDBM30288(indole-based 6-membered lactam, (R)-4b)
Affinity DataIC50: 160nMpH: 7.6 T: 2°CAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30299BDBM30299(indole-based 7-membered lactam, 23b)
Affinity DataIC50: 190nMAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30281BDBM30281(indole-based 6-membered lactam, 3e)
Affinity DataIC50: 210nMpH: 7.6 T: 2°CAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30277BDBM30277(indole-based 6-membered lactam, 3a)
Affinity DataIC50: 260nMpH: 7.6 T: 2°CAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30298BDBM30298(indole-based 7-membered lactam, 23a)
Affinity DataIC50: 270nMAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30307BDBM30307(indole-based 7-membered lactam, 25h)
Affinity DataIC50: 310nMAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30284BDBM30284(indole-based 6-membered lactam, (R)-4a)
Affinity DataIC50: 320nMpH: 7.6 T: 2°CAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30301BDBM30301(indole-based 7-membered lactam, 25d)
Affinity DataIC50: 320nMAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30304BDBM30304(indole-based 7-membered lactam, 25e)
Affinity DataIC50: 530nMAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30290BDBM30290(indole-based 6-membered lactam, 4c)
Affinity DataIC50: 550nMpH: 7.6 T: 2°CAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30306BDBM30306(indole-based 7-membered lactam, 25g)
Affinity DataIC50: 560nMAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30292BDBM30292(indole-based 6-membered lactam, 4f)
Affinity DataIC50: 580nMpH: 7.6 T: 2°CAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30305BDBM30305(indole-based 7-membered lactam, 25f)
Affinity DataIC50: 690nMAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30280BDBM30280(indole-based 6-membered lactam, 3d)
Affinity DataIC50: 1.00E+3nMpH: 7.6 T: 2°CAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30287BDBM30287(indole-based 6-membered lactam, 22)
Affinity DataIC50: 1.10E+3nMpH: 7.6 T: 2°CAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30278BDBM30278(indole-based 6-membered lactam, 3c)
Affinity DataIC50: 1.20E+3nMpH: 7.6 T: 2°CAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30286BDBM30286(indole-based 6-membered lactam, 4d)
Affinity DataIC50: 1.20E+3nMpH: 7.6 T: 2°CAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30308BDBM30308(indole-based 7-membered lactam, 25i)
Affinity DataIC50: 1.20E+3nMAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30289BDBM30289(indole-based 6-membered lactam, (S)-4b)
Affinity DataIC50: 1.40E+3nMpH: 7.6 T: 2°CAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30283BDBM30283(indole-based 6-membered lactam, 2)
Affinity DataIC50: 1.70E+3nMpH: 7.6 T: 2°CAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30285BDBM30285(indole-based 6-membered lactam, (S)-4a)
Affinity DataIC50: 2.30E+3nMpH: 7.6 T: 2°CAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30276BDBM30276(indole-based 6-membered lactam, 1)
Affinity DataIC50: 2.60E+3nMpH: 7.6 T: 2°CAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30293BDBM30293(indole-based 6-membered lactam, 4g)
Affinity DataIC50: 3.00E+3nMpH: 7.6 T: 2°CAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30294BDBM30294(indole-based 6-membered lactam, 4h)
Affinity DataIC50: 4.00E+3nMpH: 7.6 T: 2°CAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30291BDBM30291(indole-based 6-membered lactam, 4e)
Affinity DataIC50: 4.00E+3nMpH: 7.6 T: 2°CAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30297BDBM30297(indole-based 6-membered lactam, 4k)
Affinity DataIC50: 6.90E+3nMpH: 7.6 T: 2°CAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30295BDBM30295(indole-based 6-membered lactam, 4i)
Affinity DataIC50: 1.00E+4nMpH: 7.6 T: 2°CAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30296BDBM30296(indole-based 6-membered lactam, 4j)
Affinity DataIC50: 1.00E+4nMpH: 7.6 T: 2°CAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2 [41-364](Human)
Boehringer Ingelheim Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 30282BDBM30282(indole-based 6-membered lactam, 3f)
Affinity DataIC50: 1.00E+4nMpH: 7.6 T: 2°CAssay Description:Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2009
Entry Details Article
PubMed