Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50038477
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009718BDBM50009718(CHEMBL7550 | 2-Ethyl-5,7-dimethyl-3-[2'-(1H-tetraz...)
Affinity DataIC50: 0.400nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009712BDBM50009712(CHEMBL315104 | 5,7-Dimethyl-2-propyl-3-[2'-(2H-tet...)
Affinity DataIC50: 0.800nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049186BDBM50049186(CHEMBL1069 | (S)-3-Methyl-2-{pentanoyl-[2'-(1H-tet...)
Affinity DataIC50: 3.40nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82258BDBM82258(NSC_3961 | CAS_114798-26-4 | Losartan)
Affinity DataIC50: 6.70nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145979BDBM50145979(4-[4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3...)
Affinity DataIC50: 6.90nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Rabbit)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376928BDBM50376928(CHEMBL259114)
Affinity DataKd:  10.5nMAssay Description:Antagonist activity at AT1 receptor in KCl-contracted rabbit aortic strips after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119657BDBM50119657(8-Butyl-7-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmeth...)
Affinity DataKi:  14nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Rabbit)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376913BDBM50376913(CHEMBL259353)
Affinity DataKd:  14.8nMAssay Description:Antagonist activity at AT1 receptor in KCl-contracted rabbit aortic strips after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376928BDBM50376928(CHEMBL259114)
Affinity DataIC50: 18nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50089990BDBM50089990(2-Butyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...)
Affinity DataKi:  25nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376913BDBM50376913(CHEMBL259353)
Affinity DataIC50: 39nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376926BDBM50376926(CHEMBL258685)
Affinity DataIC50: 53nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376919BDBM50376919(CHEMBL408188)
Affinity DataIC50: 70nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376918BDBM50376918(CHEMBL262098)
Affinity DataIC50: 76nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50119658BDBM50119658(7-Butyl-8-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...)
Affinity DataKi:  80nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376922BDBM50376922(CHEMBL410105)
Affinity DataIC50: 81nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376912BDBM50376912(CHEMBL265208)
Affinity DataIC50: 90nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376907BDBM50376907(CHEMBL410325)
Affinity DataIC50: 95nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376930BDBM50376930(CHEMBL409744)
Affinity DataIC50: 108nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376903BDBM50376903(CHEMBL260578)
Affinity DataIC50: 114nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376927BDBM50376927(CHEMBL261765)
Affinity DataIC50: 124nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376916BDBM50376916(CHEMBL265958)
Affinity DataIC50: 124nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376905BDBM50376905(CHEMBL258891)
Affinity DataIC50: 146nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376908BDBM50376908(CHEMBL261248)
Affinity DataIC50: 154nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376921BDBM50376921(CHEMBL408227)
Affinity DataIC50: 168nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Rabbit)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82258BDBM82258(NSC_3961 | CAS_114798-26-4 | Losartan)
Affinity DataKd:  200nMAssay Description:Antagonist activity at AT1 receptor in KCl-contracted rabbit aortic strips after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376904BDBM50376904(CHEMBL409722)
Affinity DataIC50: 254nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376917BDBM50376917(CHEMBL409095)
Affinity DataIC50: 258nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376923BDBM50376923(CHEMBL265452)
Affinity DataIC50: 291nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376920BDBM50376920(CHEMBL259575)
Affinity DataIC50: 427nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376911BDBM50376911(CHEMBL410487)
Affinity DataIC50: 461nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376906BDBM50376906(CHEMBL410125)
Affinity DataIC50: 598nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376915BDBM50376915(CHEMBL427738)
Affinity DataIC50: 600nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376924BDBM50376924(CHEMBL265697)
Affinity DataIC50: 1.87E+3nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376929BDBM50376929(CHEMBL259116)
Affinity DataIC50: 2.30E+3nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376925BDBM50376925(CHEMBL258684)
Affinity DataIC50: 3.00E+3nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376914BDBM50376914(CHEMBL408187)
Affinity DataIC50: 3.00E+3nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376909BDBM50376909(CHEMBL259397)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor A(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50376910BDBM50376910(CHEMBL264946)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed